Skip to main content
Top
Published in: Acta Neurochirurgica 1/2017

01-01-2017 | Case Report - Vascular

Cerebral amyloid angiopathy in a young man with a history of traumatic brain injury: a case report and review of the literature

Authors: Yoichi Nakayama, Yohei Mineharu, Yoshiki Arawaka, Sei Nishida, Hirofumi Tsuji, Hidehiko Miyake, Maki Yamaguchi, Sachiko Minamiguchi, Yasushi Takagi, Susumu Miyamoto

Published in: Acta Neurochirurgica | Issue 1/2017

Login to get access

Abstract

Cerebral amyloid angiopathy (CAA), a cause of recurrent and multiple lobar hemorrhages, characteristically occurs in persons aged ≥55 years. We report a case of a 32-year-old male who had recurrent hemorrhage in the left multiple lobes, with a history of traumatic brain injury and hematoma evacuation at the age of 1 year. He underwent surgical treatment and was histopathologically diagnosed as having CAA. The literature review yielded six CAA cases, including ours, aged less than 55 years. All were male and four had histories of severe TBI, suggesting that male sex and TBI may be associated with CAA in young persons.
Literature
1.
go back to reference Campbell DM, Bruins S, Vogel H, Shuer LM, Wijman CAC (2008) Intracerebral hemorrhage caused by cerebral amyloid angiopathy in a 53-year-old man. J Neurol 255(4):597–598CrossRefPubMed Campbell DM, Bruins S, Vogel H, Shuer LM, Wijman CAC (2008) Intracerebral hemorrhage caused by cerebral amyloid angiopathy in a 53-year-old man. J Neurol 255(4):597–598CrossRefPubMed
2.
go back to reference Ehling R, Helbok R, Beer R, Lackner P, Broessner G, Pfausler B, Röcken C, Aguzzi A, Chemelli A, Schmutzhard E (2012) Recurrent intracerebral haemorrhage after coitus: a case report of sporadic cerebral amyloid angiopathy in a younger patient. Eur J Neurol 19(3):29–31CrossRef Ehling R, Helbok R, Beer R, Lackner P, Broessner G, Pfausler B, Röcken C, Aguzzi A, Chemelli A, Schmutzhard E (2012) Recurrent intracerebral haemorrhage after coitus: a case report of sporadic cerebral amyloid angiopathy in a younger patient. Eur J Neurol 19(3):29–31CrossRef
3.
go back to reference Fleminger S, Oliver DL, Lovestone S, Rabe-Hesketh S, Giora A (2003) Head injury as a risk factor for Alzheimer’s disease: the evidence 10 years on; a partial replication. J Neurol Neurosurg Psychiatry 74(7):857–862CrossRefPubMedPubMedCentral Fleminger S, Oliver DL, Lovestone S, Rabe-Hesketh S, Giora A (2003) Head injury as a risk factor for Alzheimer’s disease: the evidence 10 years on; a partial replication. J Neurol Neurosurg Psychiatry 74(7):857–862CrossRefPubMedPubMedCentral
4.
go back to reference Gilbert JJ, Vinters HV (1983) Cerebral amyloid angiopathy: incidence and complications in the aging brain. I. Cerebral hemorrhage. Stroke 14(6):915–923CrossRefPubMed Gilbert JJ, Vinters HV (1983) Cerebral amyloid angiopathy: incidence and complications in the aging brain. I. Cerebral hemorrhage. Stroke 14(6):915–923CrossRefPubMed
5.
go back to reference Magnoni S, Brody DL (2010) New perspectives on amyloid-beta dynamics after acute brain injury: moving between experimental approaches and studies in the human brain. Arch Neurol 67(9):1068–1073CrossRefPubMed Magnoni S, Brody DL (2010) New perspectives on amyloid-beta dynamics after acute brain injury: moving between experimental approaches and studies in the human brain. Arch Neurol 67(9):1068–1073CrossRefPubMed
6.
go back to reference Mortimer JA, French LR, Hutton JT, Schuman LM (1985) Head injury as a risk factor for Alzheimer’s disease. Neurology 35(2):264–267CrossRefPubMed Mortimer JA, French LR, Hutton JT, Schuman LM (1985) Head injury as a risk factor for Alzheimer’s disease. Neurology 35(2):264–267CrossRefPubMed
7.
go back to reference Purrucker JC, Hund E, Ringleb PA, Hartmann C, Rohde S, Schönland S, Steiner T (2013) Cerebral amyloid angiopathy—an underdiagnosed entity in younger adults with lobar intracerebral hemorrhage? Amyloid 20(1):45–47CrossRefPubMed Purrucker JC, Hund E, Ringleb PA, Hartmann C, Rohde S, Schönland S, Steiner T (2013) Cerebral amyloid angiopathy—an underdiagnosed entity in younger adults with lobar intracerebral hemorrhage? Amyloid 20(1):45–47CrossRefPubMed
8.
go back to reference Shinohara M, DeTure M, Yamazaki Y, Tachibana M, Atagi Y, Davis MD, Liu C-C, Zhao N, Painter MM, Petersen RC, Fryer JD, Crook JE, Dickson DW, Bu G, Kanekiyo T (2016) Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease. Acta Neuropathol 132(2):225–234CrossRefPubMed Shinohara M, DeTure M, Yamazaki Y, Tachibana M, Atagi Y, Davis MD, Liu C-C, Zhao N, Painter MM, Petersen RC, Fryer JD, Crook JE, Dickson DW, Bu G, Kanekiyo T (2016) Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease. Acta Neuropathol 132(2):225–234CrossRefPubMed
9.
go back to reference Smith EE, Greenberg SM (2003) Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Curr Atheroscler Rep 5(4):260–266CrossRefPubMed Smith EE, Greenberg SM (2003) Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Curr Atheroscler Rep 5(4):260–266CrossRefPubMed
10.
go back to reference Wong MP, Ng TH, Chan KH (1991) Cerebral amyloid angiopathy and spontaneous intracerebral haemorrhage. Report of a sporadic case in a young Chinese. Clin Neurol Neurosurg 93(2):133–136CrossRefPubMed Wong MP, Ng TH, Chan KH (1991) Cerebral amyloid angiopathy and spontaneous intracerebral haemorrhage. Report of a sporadic case in a young Chinese. Clin Neurol Neurosurg 93(2):133–136CrossRefPubMed
11.
go back to reference Yamada M (2000) Cerebral amyloid angiopathy: an overview. Neuropathology 1:8–22CrossRef Yamada M (2000) Cerebral amyloid angiopathy: an overview. Neuropathology 1:8–22CrossRef
Metadata
Title
Cerebral amyloid angiopathy in a young man with a history of traumatic brain injury: a case report and review of the literature
Authors
Yoichi Nakayama
Yohei Mineharu
Yoshiki Arawaka
Sei Nishida
Hirofumi Tsuji
Hidehiko Miyake
Maki Yamaguchi
Sachiko Minamiguchi
Yasushi Takagi
Susumu Miyamoto
Publication date
01-01-2017
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 1/2017
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-016-3004-0

Other articles of this Issue 1/2017

Acta Neurochirurgica 1/2017 Go to the issue