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Acta Neurochirurgica
Published in: Acta Neurochirurgica 12/2016

01-12-2016 | Case Report - History of Neurosurgery

Biofilm-associated infection: the hidden face of cerebrospinal fluid shunt malfunction

Authors: Roman Mounier, Natacha Kapandji, Ron Birnbaum, Fabrice Cook, Cristophe Rodriguez, Bibba Nebbad, David Lobo, Gilles Dhonneur

Published in: Acta Neurochirurgica | Issue 12/2016

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Abstract

Diagnosis of cerebrospinal fluid (CSF) shunt infection is difficult. Growing evidence links this pattern to biofilm-associated infections (BAI). Biofilm may explain the indolent development of the infection, and the poor efficiency of traditional microbiologic methods. We report the case of a patient admitted for hydrocephalus associated to CSF shunt malfunction. None of the clinical, serum, or CSF laboratory findings were in favor of an infectious process. Only scanning electron microscopy (SEM) revealed the presence of biofilm. Hence, despite a broad CSF shunt infection definition, some infections could remain undiagnosed by the traditional approach. This study is the first to provide some direct evidence for bacterial biofilm-associated CSF shunt infection.
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Metadata
Title
Biofilm-associated infection: the hidden face of cerebrospinal fluid shunt malfunction
Authors
Roman Mounier
Natacha Kapandji
Ron Birnbaum
Fabrice Cook
Cristophe Rodriguez
Bibba Nebbad
David Lobo
Gilles Dhonneur
Publication date
01-12-2016
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 12/2016
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-016-2977-z

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