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01-07-2016 | Clinical Article - Brain Tumors

Surgical resection of medulla oblongata hemangioblastomas: outcome and complications

Authors: Lorenzo Giammattei, Mahmoud Messerer, Nozar Aghakhani, Philippe David, Anne Herbrecht, Stéphane Richard, Fabrice Parker

Published in: Acta Neurochirurgica | Issue 7/2016

Abstract

Object

The purpose of this study was to analyze the surgical outcome and complications of a single-center series of medulla oblongata (MO) hemangioblastomas.

Methods

We retrospectively reviewed the medical charts of all medulla oblongata hemangioblastomas operated on at our institution between 1996 and 2015. All patients had a pre- and postoperative MRI and a minimum follow-up of 6 months. Patients were scored according to the Karnofsky Performance Scale (KPS) and McCormick Scale at the moment of admission, discharge and the last follow-up.

Results

Thirty-one surgical procedures were performed on 27 patients (16 females and 11 males). The mean age was 33 years, and 93 % of patients had von Hippel Lindau (VHL) disease. Three patients experienced very complicated postoperative courses, with one case ending in the death of the patient. Two patients required tracheostomy. According to McCormick’s classification, 7 (23 %) of the 31 operations resulted in aggravation and 23 (74 %) in no change. Considering the seven patients with aggravation at discharge, four patients (60 %) returned to their preoperative status, one (14 %) improved but remained below his preoperative McCormick grade and two (29 %) did not improve. At last follow-up, KPS was ameliorated in 53 %, stable in 40 % and worsened in 7 % of cases.

Conclusion

Surgery of medulla oblongata hemangioblastomas is a challenging procedure characterized by an acceptable morbidity. Transient morbidity is not negligible even if the long-term outcome is in most cases favorable. A compromised neurological condition seems to be the best predictor of unfavorable outcome.

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Title: Surgical resection of medulla oblongata hemangioblastomas: outcome and complications
Authors: Lorenzo Giammattei
Mahmoud Messerer
Nozar Aghakhani
Philippe David
Anne Herbrecht
Stéphane Richard
Fabrice Parker
Publication date: 01-07-2016
Publisher: Springer Vienna
Published in: Acta Neurochirurgica / Issue 7/2016
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI: https://doi.org/10.1007/s00701-016-2834-0

At a glance: The STEP trials

Springer Medicine

Surgical resection of medulla oblongata hemangioblastomas: outcome and complications

Abstract

Object

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Object

Methods

Results

Conclusion

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