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Published in: Acta Neurochirurgica 6/2012

01-06-2012 | Clinical Article

Treatment of intra-cranial aneurysms with the SILK flow diverter: 2 years’ experience with 28 patients at a single center

Authors: Shimon Maimon, Lior Gonen, Erez Nossek, Ido Strauss, Ronen Levite, Zvi Ram

Published in: Acta Neurochirurgica | Issue 6/2012

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Abstract

Background

Flow diverters are recently developed stent-like endovascular devices developed to treat complex and non-coilable aneurysms. SILK is a type of flow diverter that has been used for nearly 3 years. Only sparse data about it are available. We would like to share our experience with this device.

Methods

Twenty-eight patients were treated with SILK from October 2008 to October 2010. Thirty-one treatment sessions were performed for 32 aneurysms using 31 SILKs. Twenty have been treated with SILK only and eight with SILK and adjuvant stents. Twenty-six (86%) patients performed cross-sectional imaging (MRA/CTA) for follow-up. Eighteen (64%) patients had follow-up brain angiography.

Results

In all patients the SILK could be deployed. No case of early or late aneurysmal rupture was noted. Five patients (17.8%) developed immediate clinical complications, which were permanent in three (10.7%). All the complications occurred in patients harboring aneurysms larger than 15 mm. In two other patients, occlusion of the SILK was noted with no clinical deficit. A complete or near-complete aneurysmal occlusion was found in brain angiography or cross-sectional imaging follow-up in 83.3% of the patients.

Conclusions

SILK is a relatively simple device to use, with a low rate of technical and clinical complications and a high short-term aneurysmal occlusion rate. In aneurysms smaller than 15 mm, the results are excellent. Results are also encouraging in the larger aneurysms, taking into consideration their complexity. The device characteristics and mainly its drawbacks must be well known by the users.
Literature
1.
go back to reference Byrne JV, Beltechi R, Yarnold JA, Birks J, Kamran M (2010) Early experience in the treatment of intra-cranial aneurysms by endovascular flow diversion: a multicentre prospective study. PLos One 5(9) pii:e12492 Byrne JV, Beltechi R, Yarnold JA, Birks J, Kamran M (2010) Early experience in the treatment of intra-cranial aneurysms by endovascular flow diversion: a multicentre prospective study. PLos One 5(9) pii:e12492
2.
go back to reference Campi A, Ramzi N, Molyneux AJ, Summers PE, Kerr RS, Sneade M, Yarnold JA, Rischmiller J, Byrne JV (2007) Retreatment of ruptured cerebral aneurysms in patients randomized by coiling or clipping in the International Subarachnoid Aneurysm Trial (ISAT). Stroke 38:1538–1544PubMedCrossRef Campi A, Ramzi N, Molyneux AJ, Summers PE, Kerr RS, Sneade M, Yarnold JA, Rischmiller J, Byrne JV (2007) Retreatment of ruptured cerebral aneurysms in patients randomized by coiling or clipping in the International Subarachnoid Aneurysm Trial (ISAT). Stroke 38:1538–1544PubMedCrossRef
3.
go back to reference Fiorella D, Woo HH, Albuquerque FC, Nelson PK (2008) Definitive reconstruction of circumferential, fusiform intracranial aneurysms with the pipeline embolization device. Neurosurgery 62:1115–1120PubMedCrossRef Fiorella D, Woo HH, Albuquerque FC, Nelson PK (2008) Definitive reconstruction of circumferential, fusiform intracranial aneurysms with the pipeline embolization device. Neurosurgery 62:1115–1120PubMedCrossRef
4.
go back to reference Friedman JA, Nichols DA, Meyer FB, Pichelmann MA, McIver JI, Toussaint LG 3rd, Axley PL, Brown RD Jr (2003) Guglielmi detachable coil treatment of ruptured saccular cerebral aneurysms: retrospective review of a 10-year single-center experience. AJNR Am J Neuroradiol 24:526–533PubMed Friedman JA, Nichols DA, Meyer FB, Pichelmann MA, McIver JI, Toussaint LG 3rd, Axley PL, Brown RD Jr (2003) Guglielmi detachable coil treatment of ruptured saccular cerebral aneurysms: retrospective review of a 10-year single-center experience. AJNR Am J Neuroradiol 24:526–533PubMed
5.
go back to reference Hayashi K, Kitagawa N, Morikawa M, Horie N, Kawakubo J, Hiu T, Tsutsumi K, Nagata I (2009) Long-term follow-up of endovascular coil embolization for cerebral aneurysms using three-dimensional time-of-flight magnetic resonance angiography. Neurol Res 31(7):674–680PubMedCrossRef Hayashi K, Kitagawa N, Morikawa M, Horie N, Kawakubo J, Hiu T, Tsutsumi K, Nagata I (2009) Long-term follow-up of endovascular coil embolization for cerebral aneurysms using three-dimensional time-of-flight magnetic resonance angiography. Neurol Res 31(7):674–680PubMedCrossRef
6.
go back to reference Higashida RT, Smith W, Gress D, Urwin R, Dowd CF, Balousek PA, Halbach VV (1997) Intravascular stent and endovascular coil placement for a ruptured fusiform aneurysm of the basilar artery. Case review and of the literature. J Neurosurg 87:944–949PubMedCrossRef Higashida RT, Smith W, Gress D, Urwin R, Dowd CF, Balousek PA, Halbach VV (1997) Intravascular stent and endovascular coil placement for a ruptured fusiform aneurysm of the basilar artery. Case review and of the literature. J Neurosurg 87:944–949PubMedCrossRef
7.
go back to reference Horie N, Kitagawa N, Morikawa M, Tsutsumi K, Kaminogo M, Nagata I (2007) Progressive perianeurysmal edema induced after endovascular coil embolization. Report of three cases and review of the literature. J Neurosurg 106(5):916–920PubMedCrossRef Horie N, Kitagawa N, Morikawa M, Tsutsumi K, Kaminogo M, Nagata I (2007) Progressive perianeurysmal edema induced after endovascular coil embolization. Report of three cases and review of the literature. J Neurosurg 106(5):916–920PubMedCrossRef
8.
go back to reference Ionita CN, Paciorek AM, Dohatcu A, Hoffmann KR, Bednarek DR, Kolega J, Levy EI, Hopkins LN, Rudin S, Mocco JD (2009) The asymmetric vascular stent: efficacy in a rabbit aneurysm model. Stroke 40:959–965PubMedCrossRef Ionita CN, Paciorek AM, Dohatcu A, Hoffmann KR, Bednarek DR, Kolega J, Levy EI, Hopkins LN, Rudin S, Mocco JD (2009) The asymmetric vascular stent: efficacy in a rabbit aneurysm model. Stroke 40:959–965PubMedCrossRef
9.
go back to reference Lubicz B, Collignon L, Raphaeli G, Pruvo JP, Bruneau M, De Witte O, Leclerc X (2010) Flow-diverter stent for the endovascular treatment ofintracranial aneurysms: a prospective study in 29 patients with 34 aneurysms. Stroke 41(10):2247–2253PubMedCrossRef Lubicz B, Collignon L, Raphaeli G, Pruvo JP, Bruneau M, De Witte O, Leclerc X (2010) Flow-diverter stent for the endovascular treatment ofintracranial aneurysms: a prospective study in 29 patients with 34 aneurysms. Stroke 41(10):2247–2253PubMedCrossRef
10.
go back to reference Lylyk P, Miranda C, Ceratto R, Ferrario A, Scrivano E, Luna HR, Berez AL, Tran Q, Nelson PK, Fiorella D (2009) Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device: the Buenos Aires experience. Neurosurgery 64:632–642PubMedCrossRef Lylyk P, Miranda C, Ceratto R, Ferrario A, Scrivano E, Luna HR, Berez AL, Tran Q, Nelson PK, Fiorella D (2009) Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device: the Buenos Aires experience. Neurosurgery 64:632–642PubMedCrossRef
11.
go back to reference Molyneux A, Kerr R, Stratton I, Sandercock P, Clarke M, Shrimpton J, Holman R (2002) International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomized trial. J Stroke Cerebrovasc Dis 11:304–314PubMedCrossRef Molyneux A, Kerr R, Stratton I, Sandercock P, Clarke M, Shrimpton J, Holman R (2002) International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomized trial. J Stroke Cerebrovasc Dis 11:304–314PubMedCrossRef
12.
go back to reference Murayama Y, Nien YL, Duckwiler G, Gobin YP, Jahan R, Frazee J, Martin N, Viñuela F (2003) Guglielmi detachable coil embolization of cerebral aneurysms: 11 years’ experience. J Neurosurg 98:959–966PubMedCrossRef Murayama Y, Nien YL, Duckwiler G, Gobin YP, Jahan R, Frazee J, Martin N, Viñuela F (2003) Guglielmi detachable coil embolization of cerebral aneurysms: 11 years’ experience. J Neurosurg 98:959–966PubMedCrossRef
13.
go back to reference Ries T, Siemonsen S, Thomalla G, Grzyska U, Zeumer H, Fiehler J (2007) Long-term follow-up of cerebral aneurysms after endovascular therapy prediction and outcome of retreatment. AJNR Am J Neuroradiol 28:1755–1761PubMedCrossRef Ries T, Siemonsen S, Thomalla G, Grzyska U, Zeumer H, Fiehler J (2007) Long-term follow-up of cerebral aneurysms after endovascular therapy prediction and outcome of retreatment. AJNR Am J Neuroradiol 28:1755–1761PubMedCrossRef
14.
go back to reference Sadasivan C, Cesar L, Seong J, Rakian A, Hao Q, Tio FO, Wakhloo AK, Lieber BB (2009) An original flow diversion device for the treatment of intracranial aneurysms: evaluation in the rabbit elastase-induced model. Stroke 40:952–958PubMedCrossRef Sadasivan C, Cesar L, Seong J, Rakian A, Hao Q, Tio FO, Wakhloo AK, Lieber BB (2009) An original flow diversion device for the treatment of intracranial aneurysms: evaluation in the rabbit elastase-induced model. Stroke 40:952–958PubMedCrossRef
15.
go back to reference Szikora I, Berentei Z, Kulcsar Z, Marosfoi M, Vajda ZS, Lee W, Berez A, Nelson PK (2010) Treatment of intracranial aneurysms by functional reconstruction of the parent artery: the Budapest experience with the Pipeline embolization device. AJNR Am J Neuroradiol 31(6):1139–1147PubMedCrossRef Szikora I, Berentei Z, Kulcsar Z, Marosfoi M, Vajda ZS, Lee W, Berez A, Nelson PK (2010) Treatment of intracranial aneurysms by functional reconstruction of the parent artery: the Budapest experience with the Pipeline embolization device. AJNR Am J Neuroradiol 31(6):1139–1147PubMedCrossRef
16.
go back to reference Thornton J, Debrun GM, Aletich VA, Bashir Q, Charbel FT, Ausman J (2002) Follow up angiography of intracranial aneurysms treated with endovascular placement of Guglielmi detachable coils. Neurosurgery 50:239–249PubMed Thornton J, Debrun GM, Aletich VA, Bashir Q, Charbel FT, Ausman J (2002) Follow up angiography of intracranial aneurysms treated with endovascular placement of Guglielmi detachable coils. Neurosurgery 50:239–249PubMed
17.
go back to reference Turowski B, Macht S, Kulcsár Z, Hänggi D, Stummer W (2011) Early fatal hemorrhage after endovascular cerebral aneurysm treatment with a flow diverter (SILK-Stent): do we need to rethink our concepts? Neuroradiology 53(1):37–41PubMedCrossRef Turowski B, Macht S, Kulcsár Z, Hänggi D, Stummer W (2011) Early fatal hemorrhage after endovascular cerebral aneurysm treatment with a flow diverter (SILK-Stent): do we need to rethink our concepts? Neuroradiology 53(1):37–41PubMedCrossRef
18.
go back to reference Vallee JN, Aymard A, Vicaut E, Reis M, Merland JJ (2003) Endovascular treatment of basilar tip aneurysms with Guglielmi detachable coils: predictors of immediate and long-term results with multivariate analysis 6-year experience. Radiology 226:867–879PubMedCrossRef Vallee JN, Aymard A, Vicaut E, Reis M, Merland JJ (2003) Endovascular treatment of basilar tip aneurysms with Guglielmi detachable coils: predictors of immediate and long-term results with multivariate analysis 6-year experience. Radiology 226:867–879PubMedCrossRef
Metadata
Title
Treatment of intra-cranial aneurysms with the SILK flow diverter: 2 years’ experience with 28 patients at a single center
Authors
Shimon Maimon
Lior Gonen
Erez Nossek
Ido Strauss
Ronen Levite
Zvi Ram
Publication date
01-06-2012
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 6/2012
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-012-1316-2

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