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Acta Neurochirurgica
Published in: Acta Neurochirurgica 1/2012

01-01-2012 | Clinical Article

Long-term cognitive dysfunction in patients with traumatic subarachnoid hemorrhage: prevalence and risk factors

Authors: George Kwok Chu Wong, Karine Ngai, Adrian Wong, Sandy Wai Lam, Vincent C. T. Mok, Janice Yeung, Timothy Rainer, Rosanna Wong, Wai Sang Poon

Published in: Acta Neurochirurgica | Issue 1/2012

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Abstract

Background

Cognition had recently been suggested as a supplement to traditional measures of neurological outcome. However, no data were available in the literature on long-term cognitive outcomes in patients with traumatic subarachnoid hemorrhage (tSAH).

Objective

We explored the long-term cognitive profiles of patients with tSAH who had returned to the community, and the risk factors associated with this event.

Methods

Patients with tSAH were contacted to obtain their consent to participate in the study of cognitive profiles and outcome. Forty-seven (42%) of 111 eligible patients completed all the assessments.

Results

Time from ictus to assessment ranged from 3 to 5 years. No difference in patient characteristics was observed between those who participated and those who did not. In patients with tSAH who had returned to the community, domain deficits and cognitive impairment were correlated with the extended Glasgow outcome scale (GOS-E), and were predicted by age and Glasgow coma scale (GCS) on admission. The accuracies of classifications were 79% and 81%, respectively. The number of domain deficits was also correlated with GOS-E, and was predicted by age, GCS on admission, and the extent of tSAH, with a total R 2 value of 50%.

Conclusions

Long-term cognitive dysfunction is common after tSAH. In addition to GCS on admission and follow-up GOS-E, the extent of tSAH is an independent risk factor for the number of cognitive domain deficits that occur.
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Metadata
Title
Long-term cognitive dysfunction in patients with traumatic subarachnoid hemorrhage: prevalence and risk factors
Authors
George Kwok Chu Wong
Karine Ngai
Adrian Wong
Sandy Wai Lam
Vincent C. T. Mok
Janice Yeung
Timothy Rainer
Rosanna Wong
Wai Sang Poon
Publication date
01-01-2012
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 1/2012
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-011-1198-8

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