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Surgery Today
Published in: Surgery Today 8/2021

01-08-2021 | Metastasis | Original Article

Well differentiated carcinoma with a poor prognosis: a retrospective analysis of papillary gastric adenocarcinoma

Authors: Xinyu Wang, Jingyu Deng, Han Liang

Published in: Surgery Today | Issue 8/2021

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Abstract

Purpose

To explore the clinicopathological features and prognosis of papillary gastric adenocarcinoma (PGC).

Methods

The subjects of this retrospective analysis were 1525 patients with gastric cancer in a single center in China.

Results

The patients with PGC were generally of advanced age and the tumor was located in the upper 1/3 of the stomach. PGC was well or moderately differentiated, with serosal infiltration, early lymph node metastasis, TNM stages I/II, liver metastasis, and a short postoperative overall survival time. Patients with the secondary pathological type of papillary adenocarcinoma presented with clinicopathological similarities to those with primary PGC. PGC was a risk factor for poor survival in both univariate and multivariate analyses.

Conclusion

Papillary gastric adenocarcinoma (PGC) showed different clinicopathological characteristics and prognosis to other types of gastric cancer (GC), even if it was not the primary pathological type. The higher the proportion of papillary adenocarcinoma in gastric cancer samples, the shorter the postoperative survival time of patients. PGC needs further multicenter studies.
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Metadata
Title
Well differentiated carcinoma with a poor prognosis: a retrospective analysis of papillary gastric adenocarcinoma
Authors
Xinyu Wang
Jingyu Deng
Han Liang
Publication date
01-08-2021
Publisher
Springer Singapore
Published in
Surgery Today / Issue 8/2021
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-021-02289-3

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