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Published in: Surgery Today 4/2021

01-04-2021 | Postoperative Pain Management | Original Article

Effectiveness of scheduled intravenous acetaminophen in the postoperative pain management of video-assisted thoracic surgery

Authors: Yoshinobu Shikatani, Junichi Soh, Kazuhiko Shien, Takeshi Kurosaki, Shinji Ohtani, Hiromasa Yamamoto, Arata Taniguchi, Mikio Okazaki, Seiichiro Sugimoto, Masaomi Yamane, Takahiro Oto, Hiroshi Morimatsu, Shinichi Toyooka

Published in: Surgery Today | Issue 4/2021

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Abstract

Purpose

The scheduled administration of intravenous acetaminophen (scheduled-IV-AcA) is one of the more effective multimodal analgesic approaches for postoperative pain in abdominal/orthopedic surgeries. However, there is little evidence concerning scheduled-IV-AcA after general thoracic surgery, especially when limited to video-assisted thoracoscopic surgery (VATS). We investigated the efficacy of scheduled-IV-AcA administration in patients after undergoing VATS.

Methods

Ninety-nine patients who underwent VATS lobectomy or segmentectomy via an 8-cm access window and 1 camera port were retrospectively reviewed by categorizing them into groups either with scheduled-IV-AcA (Group AcA: n = 29) or without it (Group non-AcA: n = 70). Group AcA received 1 g of IV-AcA every 6 h from the end of the operation until the end of POD2. Postoperative pain was measured using a numeric rating scale (NRS) three times per day until discharge.

Results

NRS scores were significantly lower in Group AcA with motion (on POD1 to the first point of POD2) than in Group non-AcA. Group non-AcA was also more likely to use additional analgesics than Group AcA (39% vs. 17%, p = 0.058).

Conclusions

Scheduled-IV-AcA administration is a safe and effective multimodal analgesic approach in patients undergoing VATS pulmonary resection via an 8-cm access window.
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Metadata
Title
Effectiveness of scheduled intravenous acetaminophen in the postoperative pain management of video-assisted thoracic surgery
Authors
Yoshinobu Shikatani
Junichi Soh
Kazuhiko Shien
Takeshi Kurosaki
Shinji Ohtani
Hiromasa Yamamoto
Arata Taniguchi
Mikio Okazaki
Seiichiro Sugimoto
Masaomi Yamane
Takahiro Oto
Hiroshi Morimatsu
Shinichi Toyooka
Publication date
01-04-2021
Publisher
Springer Singapore
Published in
Surgery Today / Issue 4/2021
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-020-02127-y

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