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Open Access 01-03-2021 | Gastrectomy | Original Article

Prognostic impact of the preoperative hemoglobin A1c levels in patients with gastric cancer surgery depends on postoperative complications

Authors: Jun Shibamoto, Katsutoshi Shoda, Takeshi Kubota, Toshiyuki Kosuga, Hidemasa Kubo, Takuma Ohashi, Hiroki Shimizu, Tomohiro Arita, Yusuke Yamamoto, Hirotaka Konishi, Ryo Morimura, Atsushi Shiozaki, Yoshiaki Kuriu, Hisashi Ikoma, Hitoshi Fujiwara, Kazuma Okamoto, Eigo Otsuji

Published in: Surgery Today | Issue 3/2021

Abstract

Purpose

The long-term prognostic impact of the hemoglobin A1c levels has not yet been evaluated in patients with gastric cancer. The present study investigated the clinical significance of the hemoglobin A1c levels in patients with gastric cancer.

Methods

We enrolled 294 patients with stage II, III, or IV gastric cancer who underwent gastrectomy. The patients were divided into high preoperative hemoglobin A1c (> 6.0%) and low preoperative hemoglobin A1c (≤ 6.0%) groups.

Results

In patients with stage III gastric cancer with severe postoperative complications, the high preoperative hemoglobin A1c group had a significantly worse prognosis than the low preoperative hemoglobin A1c group (p = 0.0409). In patients without severe postoperative complications, the high preoperative hemoglobin A1c group had a significantly favorable prognosis compared with the low preoperative hemoglobin A1c group (p = 0.0348).

Conclusion

The prognosis of patients with stage III gastric cancer having high preoperative hemoglobin A1c levels greatly depended on the presence or absence of postoperative complications. To avoid postoperative complications, optimal perioperative management and personalized treatments are critical, particularly for these patients.

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Title: Prognostic impact of the preoperative hemoglobin A1c levels in patients with gastric cancer surgery depends on postoperative complications
Authors: Jun Shibamoto
Katsutoshi Shoda
Takeshi Kubota
Toshiyuki Kosuga
Hidemasa Kubo
Takuma Ohashi
Hiroki Shimizu
Tomohiro Arita
Yusuke Yamamoto
Hirotaka Konishi
Ryo Morimura
Atsushi Shiozaki
Yoshiaki Kuriu
Hisashi Ikoma
Hitoshi Fujiwara
Kazuma Okamoto
Eigo Otsuji
Publication date: 01-03-2021
Publisher: Springer Singapore
Keywords: Gastrectomy
Gastric Cancer
Gastric Cancer
Hyperglycemia
Gastrectomy
Published in: Surgery Today / Issue 3/2021
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-020-02103-6

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Prognostic impact of the preoperative hemoglobin A1c levels in patients with gastric cancer surgery depends on postoperative complications

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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