Skip to main content
Top
Published in: Surgery Today 11/2020

01-11-2020 | Laparotomy | Original Article

Subcutaneous fat area as a risk factor for extraction site incisional hernia following gastrectomy for gastric cancer

Authors: Sheryl Valencia, Koji Shindo, Taiki Moriyama, Kenoki Ohuchida, Daisuke Tsurumaru, Michael Chua, Hsiang-Chih Chen, Lei Yao, Takao Ohtsuka, Shuji Shimizu, Masafumi Nakamura

Published in: Surgery Today | Issue 11/2020

Login to get access

Abstract

Purpose

To identify the incidence of extraction site incisional hernia following gastrectomy for gastric cancer and its significant risk factors, including the subcutaneous fat area.

Methods

We reviewed data gathered prospectively on patients with gastric cancer, who underwent gastrectomy between 2008 and 2012 at Kyushu University Hospital, Fukuoka, Japan. The subcutaneous fat area (SFA) and visceral fat area (VFA) were measured using axial computed tomography at the level of the L4 and L3 transverse processes, and the L2–L3 intervertebral disc. The primary endpoint of the rate of extraction site incisional hernia was based on the computed tomography and clinical data including hospital follow-up reports.

Results

After applying the inclusion and exclusion criteria, 320 patients were included in this retrospective analysis: 3.1% (10/320) had extraction site incisional hernias after a mean follow-up of 11 months. Multivariate analysis revealed that age and the SFA were independent risk factors (age ≥ 70.5 years: P = .013, odds ratio: 9.116, 95% confidence interval 1.581–52.553; L4 SFA ≥ 124 cm2: P = .004, odds ratio: 13.752, 95% confidence interval 2.290–82.582).

Conclusion

Age and the SFA were independent risk factors for extraction site incisional hernia in patients undergoing gastrectomy for gastric cancer.
Literature
1.
go back to reference Itatsu K, Yokoyama Y, Sugawara G, Kubota H, Tojima Y, Kurumiya Y, et al. Incidence of and risk factors for incisional hernia after abdominal surgery. Br J Surg. 2014;101:1439–47.PubMedCrossRef Itatsu K, Yokoyama Y, Sugawara G, Kubota H, Tojima Y, Kurumiya Y, et al. Incidence of and risk factors for incisional hernia after abdominal surgery. Br J Surg. 2014;101:1439–47.PubMedCrossRef
2.
go back to reference Eker HH, Hansson BME, Buunen M, Janssen IMC, Pierik REGJM, Hop WC, et al. Laparoscopic vs open incisional hernia repair. JAMA Surg. 2013;148:259–63.PubMedCrossRef Eker HH, Hansson BME, Buunen M, Janssen IMC, Pierik REGJM, Hop WC, et al. Laparoscopic vs open incisional hernia repair. JAMA Surg. 2013;148:259–63.PubMedCrossRef
3.
go back to reference Burger JWA, Luijendijk RW, Hop WCJ, Halm JA, Verdaasdonk EGG, Jeekel J, et al. Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia. Ann Surg. 2004;240:578–85.PubMedPubMedCentral Burger JWA, Luijendijk RW, Hop WCJ, Halm JA, Verdaasdonk EGG, Jeekel J, et al. Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia. Ann Surg. 2004;240:578–85.PubMedPubMedCentral
5.
go back to reference Nieuwenhuizen J, Kleinrensink GJ, Hop WCJ, Jeekel J, Lange JF. Indications for incisional hernia repair: an international questionnaire among hernia surgeons. Hernia. 2008;12:223–5.PubMedCrossRef Nieuwenhuizen J, Kleinrensink GJ, Hop WCJ, Jeekel J, Lange JF. Indications for incisional hernia repair: an international questionnaire among hernia surgeons. Hernia. 2008;12:223–5.PubMedCrossRef
6.
go back to reference van ’t Riet M, Steyerberg EW, Nellensteyn J, Bonjer HJ, Jeekel J. Meta-analysis of techniques for closure of midline abdominal incisions. Br J Surg. 2003;89:1350–6.CrossRef van ’t Riet M, Steyerberg EW, Nellensteyn J, Bonjer HJ, Jeekel J. Meta-analysis of techniques for closure of midline abdominal incisions. Br J Surg. 2003;89:1350–6.CrossRef
8.
go back to reference Diener MK, Voss S, Jensen K, Büchler MW, Seiler CM. Elective midline laparotomy closure. Ann Surg. 2010;251:843–56.PubMedCrossRef Diener MK, Voss S, Jensen K, Büchler MW, Seiler CM. Elective midline laparotomy closure. Ann Surg. 2010;251:843–56.PubMedCrossRef
9.
go back to reference Shiroshita H, Inomata M, Bandoh T, Uchida H, Akira S, Hashizume M, et al. Endoscopic surgery in Japan: The 13th national survey (2014–2015) by the Japan Society for Endoscopic Surgery. Asian J Endosc Surg. 2019;12:7–18.PubMedCrossRef Shiroshita H, Inomata M, Bandoh T, Uchida H, Akira S, Hashizume M, et al. Endoscopic surgery in Japan: The 13th national survey (2014–2015) by the Japan Society for Endoscopic Surgery. Asian J Endosc Surg. 2019;12:7–18.PubMedCrossRef
10.
go back to reference Jang EJ, Kim M-C, Nam S-H. Risk factors for the development of incisional hernia in mini-laparotomy wounds following laparoscopic distal gastrectomy in patients with gastric cancer. J Gastric Cancer. 2018;18:392.PubMedPubMedCentralCrossRef Jang EJ, Kim M-C, Nam S-H. Risk factors for the development of incisional hernia in mini-laparotomy wounds following laparoscopic distal gastrectomy in patients with gastric cancer. J Gastric Cancer. 2018;18:392.PubMedPubMedCentralCrossRef
12.
go back to reference Yamamoto M, Takakura Y, Ikeda S, Itamoto T, Urushihara T, Egi H. Visceral obesity is a significant risk factor for incisional hernia after laparoscopic colorectal surgery: a single-center review. Asian J Endosc Surg. 2018;11:373–7.PubMedCrossRef Yamamoto M, Takakura Y, Ikeda S, Itamoto T, Urushihara T, Egi H. Visceral obesity is a significant risk factor for incisional hernia after laparoscopic colorectal surgery: a single-center review. Asian J Endosc Surg. 2018;11:373–7.PubMedCrossRef
13.
go back to reference Lee L, Abou-Khalil M, Liberman S, Boutros M, Fried GM, Feldman LS. Incidence of incisional hernia in the specimen extraction site for laparoscopic colorectal surgery: systematic review and meta-analysis. Surg Endosc. 2017;31:5083–93.PubMedCrossRef Lee L, Abou-Khalil M, Liberman S, Boutros M, Fried GM, Feldman LS. Incidence of incisional hernia in the specimen extraction site for laparoscopic colorectal surgery: systematic review and meta-analysis. Surg Endosc. 2017;31:5083–93.PubMedCrossRef
14.
go back to reference Muysoms FE, Antoniou SA, Bury K, Campanelli G, Conze J, Cuccurullo D, et al. European Hernia Society guidelines on the closure of abdominal wall incisions. Hernia. 2015;19:1–24.PubMedCrossRef Muysoms FE, Antoniou SA, Bury K, Campanelli G, Conze J, Cuccurullo D, et al. European Hernia Society guidelines on the closure of abdominal wall incisions. Hernia. 2015;19:1–24.PubMedCrossRef
15.
go back to reference Alnassar S, Bawahab M, Abdoh A, Guzman R, Al Tuwaijiri T, Louridas G. Incisional hernia postrepair of abdominal aortic occlusive and aneurysmal disease: five-year incidence. Vascular. 2012;20:273–7.PubMedCrossRef Alnassar S, Bawahab M, Abdoh A, Guzman R, Al Tuwaijiri T, Louridas G. Incisional hernia postrepair of abdominal aortic occlusive and aneurysmal disease: five-year incidence. Vascular. 2012;20:273–7.PubMedCrossRef
16.
go back to reference Yamada T, Okabayashi K, Hasegawa H, Tsuruta M, Abe Y, Ishida T, et al. Age, preoperative subcutaneous fat area, and open laparotomy are risk factors for incisional hernia following colorectal cancer surgery. Ann Surg Oncol. 2016;23:236–41.CrossRef Yamada T, Okabayashi K, Hasegawa H, Tsuruta M, Abe Y, Ishida T, et al. Age, preoperative subcutaneous fat area, and open laparotomy are risk factors for incisional hernia following colorectal cancer surgery. Ann Surg Oncol. 2016;23:236–41.CrossRef
17.
go back to reference Tokunaga M, Hiki N, Fukunaga T, Ogura T, Miyata S, Yamaguchi T. Effect of individual fat areas on early surgical outcomes after open gastrectomy for gastric cancer. Br J Surg. 2009;96:496–500.PubMedCrossRef Tokunaga M, Hiki N, Fukunaga T, Ogura T, Miyata S, Yamaguchi T. Effect of individual fat areas on early surgical outcomes after open gastrectomy for gastric cancer. Br J Surg. 2009;96:496–500.PubMedCrossRef
18.
go back to reference Kim JH, Kim J, Lee WJ, Seong H, Choi H, Ahn JY, et al. A high visceral-to-subcutaneous fat ratio is an independent predictor of surgical site infection after gastrectomy. J Clin Med. 2019;8:494.PubMedCentralCrossRef Kim JH, Kim J, Lee WJ, Seong H, Choi H, Ahn JY, et al. A high visceral-to-subcutaneous fat ratio is an independent predictor of surgical site infection after gastrectomy. J Clin Med. 2019;8:494.PubMedCentralCrossRef
19.
go back to reference Yoshikawa K, Shimada M, Kurita N, Iwata T, Nishioka M, Morimoto S, et al. Visceral fat area is superior to body mass index as a predictive factor for risk with laparoscopy-assisted gastrectomy for gastric cancer. Surg Endosc. 2011;25:3825–30.PubMedCrossRef Yoshikawa K, Shimada M, Kurita N, Iwata T, Nishioka M, Morimoto S, et al. Visceral fat area is superior to body mass index as a predictive factor for risk with laparoscopy-assisted gastrectomy for gastric cancer. Surg Endosc. 2011;25:3825–30.PubMedCrossRef
20.
go back to reference So R, Matsuo T, Sasai H, Eto M, Tsujimoto T, Saotome K, et al. Best single-slice measurement site for estimating visceral adipose tissue volume after weight loss in obese. Japan men Nutr Metab. 2012;9:1.CrossRef So R, Matsuo T, Sasai H, Eto M, Tsujimoto T, Saotome K, et al. Best single-slice measurement site for estimating visceral adipose tissue volume after weight loss in obese. Japan men Nutr Metab. 2012;9:1.CrossRef
21.
go back to reference Kodera Y, Sano T. Japanese gastric cancer treatment guidelines 2014 (ver. 4). Gastric Cancer. 2017;20:1–19.CrossRef Kodera Y, Sano T. Japanese gastric cancer treatment guidelines 2014 (ver. 4). Gastric Cancer. 2017;20:1–19.CrossRef
23.
go back to reference Fink C, Baumann P, Wente MN, Knebel P, Bruckner T, Ulrich A, et al. Incisional hernia rate 3 years after midline laparotomy. Br J Surg. 2014;101:51–4.PubMedCrossRef Fink C, Baumann P, Wente MN, Knebel P, Bruckner T, Ulrich A, et al. Incisional hernia rate 3 years after midline laparotomy. Br J Surg. 2014;101:51–4.PubMedCrossRef
26.
27.
go back to reference Radu P, Brãtucu M, Garofil D, Goleanu V, Popa F, Strâmbu V. The role of collagen metabolism in the formation and relapse of incisional hernia. Chirurgia (Bucur). 2015;110(3):224–30. Radu P, Brãtucu M, Garofil D, Goleanu V, Popa F, Strâmbu V. The role of collagen metabolism in the formation and relapse of incisional hernia. Chirurgia (Bucur). 2015;110(3):224–30.
28.
go back to reference Caglià P, Tracia A, Borzì L, Amodeo L, Tracia L, Veroux M, et al. Incisional hernia in the elderly: Risk factors and clinical considerations. Int J Surg. 2014;12:S164–S169169.PubMedCrossRef Caglià P, Tracia A, Borzì L, Amodeo L, Tracia L, Veroux M, et al. Incisional hernia in the elderly: Risk factors and clinical considerations. Int J Surg. 2014;12:S164–S169169.PubMedCrossRef
29.
go back to reference Noshiro H, Shimizu S, Nagai E, Ohuchida K, Tanaka M. Laparoscopy-assisted distal gastrectomy for early gastric cancer: is it beneficial for patients of heavier weight? Ann Surg. 2003;238:680–5.PubMedPubMedCentralCrossRef Noshiro H, Shimizu S, Nagai E, Ohuchida K, Tanaka M. Laparoscopy-assisted distal gastrectomy for early gastric cancer: is it beneficial for patients of heavier weight? Ann Surg. 2003;238:680–5.PubMedPubMedCentralCrossRef
30.
go back to reference Amato B, Compagna R, Fappiano F, Rossi R, Bianco T, Danzi M, et al. Day-surgery inguinal hernia repair in the elderly: single centre experience. BMC Surg. 2013;13:S28.PubMedPubMedCentralCrossRef Amato B, Compagna R, Fappiano F, Rossi R, Bianco T, Danzi M, et al. Day-surgery inguinal hernia repair in the elderly: single centre experience. BMC Surg. 2013;13:S28.PubMedPubMedCentralCrossRef
31.
go back to reference Kim H, Bruen K, Vargo D. Acellular dermal matrix in the management of high-risk abdominal wall defects. Am J Surg. 2006;192:705–9.PubMedCrossRef Kim H, Bruen K, Vargo D. Acellular dermal matrix in the management of high-risk abdominal wall defects. Am J Surg. 2006;192:705–9.PubMedCrossRef
32.
go back to reference Sauerland S, Korenkov M, Kleinen T, Arndt M, Paul A. Obesity is a risk factor for recurrence after incisional hernia repair. Hernia. 2004;8:42–6.PubMedCrossRef Sauerland S, Korenkov M, Kleinen T, Arndt M, Paul A. Obesity is a risk factor for recurrence after incisional hernia repair. Hernia. 2004;8:42–6.PubMedCrossRef
Metadata
Title
Subcutaneous fat area as a risk factor for extraction site incisional hernia following gastrectomy for gastric cancer
Authors
Sheryl Valencia
Koji Shindo
Taiki Moriyama
Kenoki Ohuchida
Daisuke Tsurumaru
Michael Chua
Hsiang-Chih Chen
Lei Yao
Takao Ohtsuka
Shuji Shimizu
Masafumi Nakamura
Publication date
01-11-2020
Publisher
Springer Singapore
Published in
Surgery Today / Issue 11/2020
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-020-02039-x

Other articles of this Issue 11/2020

Surgery Today 11/2020 Go to the issue