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01-10-2020 | Letter to the Editor

Reply to the letter

Authors: Hirohisa Okabe, Yo-ichi Yamashita, Hatem A. Elmezayen, Hiromitsu Hayashi, Katsunori Imai, Hideo Baba

Published in: Surgery Today | Issue 10/2020

Excerpt

Grizzi et al. suggested the importance of a scientific method to quantitatively or semi-quantitatively evaluate liver fibrosis, which was missing in our latest report, ‘Clinical role of serum programmed death ligand 1 in patients with hepatocellular carcinoma: Where does it come from?’ [1] In this report, we investigated the role of serum programmed death ligand 1 (PD-L1) level by analyzing both the serum PD-L1 level and the tissue PD-L1 expression status in the tumor and the corresponding background liver by an immunological approach. Grizzi et al. indicated that the New Inuyama Classification [2] was based on the grade of fibrosis, which should be quantitatively discriminated. They recommend their original methodology, which would enable us to quantitatively or semi-quantitatively determine the extent of liver fibrosis [3]. …

Elmezayen HA, Okabe H, Baba Y, Yusa T, Itoyama R, Nakao Y, et al. Clinical role of serum programmed death ligand 1 in patients with hepatocellular carcinoma: Where does it come from? Surg Today. (in press)

Ichida F, Tsuji T, Omata M, Ichida T, Inoue K, Kamimura T, et al. New Inuyama classification; new criteria for histological assessment of chronic hepatitis. Int Hepatol Commun. 1996;6:112–9.CrossRef

Chiriva-Internati M, Grizzi F, Bright RK, Martin Kast W. Cancer immunotherapy: avoiding the road to perdition. J Transl. Med. 2004;2:26.CrossRef

Okabe H, Beppu T, Hayashi H, Horino K, Masuda T, Komori H, et al. Hepatic stellate cells may relate to progression of intrahepatic cholangiocarcinoma. Ann Surg Oncol. 2009;16:2555–644.CrossRef

Shirabe K, Bekki Y, Gantumor D, Araki K, Ishii N, Kuno A, et al. Mac-2 binding protein glycan isomer (M2BPGi) is a new serum biomarker for assessing liver fibrosis: more than a biomarker of liver fibrosis. J Gastroenterol. 2018;53:819–26.CrossRef

Okabe H, Beppu T, Chikamoto A, Hayashi H, Yoshida M, Masuda T, et al. Remnant liver volume-based predictors of postoperative liver dysfunction after hepatectomy: analysis of 625 consecutive patients from a single institution. Int J Clin Oncol. 2014;19:614–21.CrossRef

Okabe H, Beppu T, Hayashi H, Mima K, Nakagawa S, Kuroki H, et al. Rank classification based on the combination of indocyanine green retention rate at 15 min and (99m)Tc-DTPA-galactosyl human serum albumin scintigraphy predicts the safety of hepatic resection. Nucl Med Commun. 2014;35:478–83.CrossRef

Title: Reply to the letter
Authors: Hirohisa Okabe
Yo-ichi Yamashita
Hatem A. Elmezayen
Hiromitsu Hayashi
Katsunori Imai
Hideo Baba
Publication date: 01-10-2020
Publisher: Springer Singapore
Published in: Surgery Today / Issue 10/2020
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-020-01999-4

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Reply to the letter

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