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Surgery Today
Published in: Surgery Today 6/2015

01-06-2015 | Original Article

Clinical outcomes of laparoscopic versus open surgery for primary tumor resection in patients with stage IV colorectal cancer with unresectable metastasis

Authors: Jong Wan Kim, Ji Won Park, Sung Chan Park, Sun Young Kim, Ji Yeon Baek, Jae Hwan Oh

Published in: Surgery Today | Issue 6/2015

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Abstract

Purpose

The aim of this study was to compare the clinical outcomes of laparoscopic surgery with those of open surgery in patients with colorectal cancer and unresectable metastasis.

Methods

We retrospectively reviewed the medical records of patients who underwent primary tumor resection of colorectal cancer with unresectable metastasis between January 2001 and December 2010.

Results

Of 280 patients, 61 underwent laparoscopic surgery and 219 underwent open surgery. Regarding the short-term outcomes, the amount of blood loss was lower in the laparoscopic group (P = 0.014), although the operation was longer in the laparoscopic group (P = 0.003). The times to flatus (P < 0.001), liquid food intake (P < 0.001), and the duration of hospital stay (P < 0.001) were shorter in the laparoscopic group. The complication rate was lower in the laparoscopic group than in the open group (P = 0.043). Although the overall survival was significantly better in the laparoscopic group in a univariate analysis, there was no significant difference in the overall survival between the two groups in a multivariate analysis (P = 0.482).

Conclusions

Laparoscopic surgery seems to be a safe and feasible option, with short-term benefit for primary tumor resection in patients with stage IV colorectal cancer with unresectable metastasis.
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Metadata
Title
Clinical outcomes of laparoscopic versus open surgery for primary tumor resection in patients with stage IV colorectal cancer with unresectable metastasis
Authors
Jong Wan Kim
Ji Won Park
Sung Chan Park
Sun Young Kim
Ji Yeon Baek
Jae Hwan Oh
Publication date
01-06-2015
Publisher
Springer Japan
Published in
Surgery Today / Issue 6/2015
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-014-1079-x

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