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Surgery Today
Published in: Surgery Today 7/2015

01-07-2015 | Original Article

Hepatic resection for hepatocellular carcinoma in super-elderly patients aged 80 years and older in the first decade of the 21st century

Authors: Akinori Nozawa, Shoji Kubo, Shigekazu Takemura, Chikaharu Sakata, Yorihisa Urata, Takayoshi Nishioka, Masahiko Kinoshita, Genya Hamano, Takahiro Uenishi, Shigefumi Suehiro

Published in: Surgery Today | Issue 7/2015

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Abstract

Purpose

We evaluated the preoperative and postoperative characteristics and prognosis of super-elderly patients with hepatocellular carcinoma (HCC).

Methods

Four hundred and thirty-one patients who underwent hepatic resection for HCC were classified into three groups according to their age at the time of surgery: super-elderly (≥80 years; n = 20), elderly (70–80 years; n = 172) and younger (<70 years; n = 239). We compared the clinical characteristics, preoperative and postoperative factors and prognosis among the groups to evaluate whether liver resection is appropriate for super-elderly patients.

Results

The liver function was not significantly different among the groups. The proportion of patients with preoperative cardiovascular and respiratory disease and hypertension was higher in the super-elderly group compared to the other groups. The super-elderly group had shorter operations and reduced hemorrhage rates compared to the other groups. Postoperative cardiovascular complications and delirium were more frequently observed in the super-elderly group. The overall and tumor-free survival rates were not significantly different among the groups. Super-elderly patients had a lower rate of liver or HCC-related death and a higher rate of death due to other causes than the other groups.

Conclusions

Super-elderly HCC patients who are appropriately evaluated and selected might have a favorable prognosis after undergoing hepatic resection.
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Metadata
Title
Hepatic resection for hepatocellular carcinoma in super-elderly patients aged 80 years and older in the first decade of the 21st century
Authors
Akinori Nozawa
Shoji Kubo
Shigekazu Takemura
Chikaharu Sakata
Yorihisa Urata
Takayoshi Nishioka
Masahiko Kinoshita
Genya Hamano
Takahiro Uenishi
Shigefumi Suehiro
Publication date
01-07-2015
Publisher
Springer Japan
Published in
Surgery Today / Issue 7/2015
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-014-0994-1

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