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Surgery Today
Published in: Surgery Today 6/2012

01-06-2012 | Original Article

The prognostic nutritional index can be a prognostic indicator in colorectal carcinoma

Authors: Tadahiro Nozoe, Mayuko Kohno, Tomohiro Iguchi, Emiko Mori, Takashi Maeda, Akito Matsukuma, Takahiro Ezaki

Published in: Surgery Today | Issue 6/2012

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Abstract

Purpose

Preoperative assessments regarding a patient’s immunological and nutritional condition are required to predict the outcomes of patients with malignant tumors. The aim of the current study was to clarify the significance of Onodera’s prognostic nutritional index (OPNI), which can simply account for the immunological and nutritional conditions, in patients with colorectal carcinoma.

Methods

The correlations of the preoperative OPNI value with clinicopathological features were examined in 219 patients with colorectal carcinoma who had been surgically treated.

Results

Not only the tumor stage (P = 0.028) and venous invasion (P = 0.002), but also an OPNI of less than 40 (P = 0.002) were found to be independently correlated with a worse prognosis of patients with colorectal carcinoma.

Conclusion

The preoperative OPNI can be used as a simple prognostic indicator in colorectal carcinoma.
Literature
1.
Delmore G. Assessment of nutritional status in cancer patients: widely neglected? Support Care Cancer. 1997;5:376–80.PubMedCrossRef
2.
Onodera T, Goseki N, Kosaki G. Prognostic nutritional index in gastrointestinal surgery of malnourished cancer patients. Nippon Geka Gakkai Zasshi. 1984;85:1001–5 (in Japanese with an English abstract).
3.
Nozoe T, Kimura Y, Ishida M, Saeki H, Korenaga D, Sugimachi K. Correlation of pre-operative nutritional condition with post-operative complications in surgical treatment for oesophageal carcinoma. Eur J Surg Oncol. 2002;28:396–400.PubMedCrossRef
4.
Nozoe T, Ninomiya M, Maeda T, Matsukuma A, Nakashima H, Ezaki T. Prognostic nutritional index: a tool to predict the biological aggressiveness of gastric carcinoma. Surg Today. 2010;40:440–3.PubMedCrossRef
5.
Japanese Society for Cancer of the Colon and Rectum. Japanese classification: colorectal carcinoma, 2nd ed. Tokyo: Kanehara; 1997.
6.
Sobin L, Gospodarowicz M, Wittekind C; International Union Against Cancer. TNM classification of malignant tumours, 7th ed. New York: Wiley-Blackwell; 2009. p. 73–7.
7.
Boonpipattanapong T, Chewatanakornkul S. Preoperative carcinoembryonic antigen and albumin in predicting survival in patients with colon and rectal carcinomas. J Clin Gastroenterol. 2006;40:592–5.PubMedCrossRef
8.
Walsh SR, Cook EJ, Goulder F, Justin TA, Keeling NJ. Neutrophil–lymphocyte ratio as a prognostic factor in colorectal cancer. J Surg Oncol. 2005;91:181–4.PubMedCrossRef
9.
Nozoe T, Yasuda M, Honda M, Inutsuka S, Korenaga D. Obstructing carcinomas of the colon and rectum have a smaller size compared with those of non-obstructing carcinomas. Oncol Rep. 2001;8:1313–5.PubMed
Metadata
Title
The prognostic nutritional index can be a prognostic indicator in colorectal carcinoma
Authors
Tadahiro Nozoe
Mayuko Kohno
Tomohiro Iguchi
Emiko Mori
Takashi Maeda
Akito Matsukuma
Takahiro Ezaki
Publication date
01-06-2012
Publisher
Springer Japan
Published in
Surgery Today / Issue 6/2012
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-011-0061-0

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