Published in:
01-01-2012 | Original Article
The central vein access port and catheter in outpatient chemotherapy for colorectal cancer: a retrospective study of 101 patients
Authors:
Hiroshi Sawayama, Naoko Hayashi, Masayuki Watanabe, Hiroshi Takamori, Toru Beppu, Hideo Baba
Published in:
Surgery Today
|
Issue 1/2012
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Abstract
Purpose
The central venous access port (CV-port) system was examined in a series of colorectal cancer (CRC) patients.
Methods
One hundred and one CRC patients underwent chemotherapy with the 5-fluorouracil + oxaliplatin (FOLFOX) or 5-fluorouracil + irinotecan regimen. The complications of the CV-port system were retrospectively assessed.
Results
The CV-port system was placed in a total of 101 patients. The patients received a total of 1035 courses of these regimens. Eight complications occurred in the 101 patients (7.9%). The complications included three instances of catheter rupture, two thrombotic events around the catheter, and three infections at the site of the port or catheter. The complications were identified after a median of nine courses (range 6–16) and 135 days after the placement of the CV-port system. Sixty-six of the 101 patients switched their regimen from FOLFOX to another regimen, and 4 of these 66 patients (6.1%) experienced complications associated with the CV-port system. There were 25 subjects who were admitted to the hospital emergency wing during the chemotherapeutic regimens, and 4 of these patients (16%) had complications associated with the CV-port system.
Conclusions
The complications of the CV-port system occurred at a defined rate, therefore the early diagnosis and the appropriate treatment to address these complications is crucial.