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European Journal of Orthopaedic Surgery & Traumatology

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01-10-2020 | Tranexamic Acid | Original Article

Prolonged operative time increases risk of blood loss and transfusion requirements in revision hip surgery

Authors: Jonathan Manara, Harvey Sandhu, Michael Wee, Adekoyejo Odutola, Thomas Wainwright, Charles Knowles, Robert Middleton

Published in: European Journal of Orthopaedic Surgery & Traumatology | Issue 7/2020

Abstract

Introduction

Revision hip surgery is well documented to have a high association with substantial blood loss and the associated need for a blood transfusion. This exposes the patient to increased risk of transfusion reaction and blood borne infection. There are many strategies to minimize allogeneic transfusion rates in revision surgery such as pre-operative autologous donation, peri-operative tranexamic acid, thrombin sealants, normovolaemic haemodilution, intra-operative blood salvage and the use of post-operative autologous drains.

Patients and methods

We prospectively looked at 177 consecutive cases performed at one centre by a single surgical and anaesthetic team to identify which patient and operative factors were most significant in minimizing the requirement for an allogeneic blood transfusion.

Results

Our results identified the duration of surgery as being the only significant variable affecting the level of blood loss. We noted a 3% increase in the probability of massive blood loss (> 2000 mls) for every minute of increased surgical time in our series.

Conclusions

We conclude that measures to minimize the duration of surgery would be beneficial in reducing blood loss and the risks of requiring blood transfusions in revision hip surgery.

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Title: Prolonged operative time increases risk of blood loss and transfusion requirements in revision hip surgery
Authors: Jonathan Manara
Harvey Sandhu
Michael Wee
Adekoyejo Odutola
Thomas Wainwright
Charles Knowles
Robert Middleton
Publication date: 01-10-2020
Publisher: Springer Paris
Keyword: Tranexamic Acid
Published in: European Journal of Orthopaedic Surgery & Traumatology / Issue 7/2020
Print ISSN: 1633-8065
Electronic ISSN: 1432-1068
DOI: https://doi.org/10.1007/s00590-020-02677-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Prolonged operative time increases risk of blood loss and transfusion requirements in revision hip surgery

Abstract

Introduction

Patients and methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Patients and methods

Results

Conclusions

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