Skip to main content
Top
Published in: European Journal of Orthopaedic Surgery & Traumatology 2/2019

01-02-2019 | Original Article • HIP - FRACTURES

Incidence, risk factors and clinical impact of postoperative delirium following open reduction and internal fixation (ORIF) for hip fractures: an analysis of 7859 patients from the ACS-NSQIP hip fracture procedure targeted database

Authors: Azeem Tariq Malik, Carmen E. Quatman, Laura S. Phieffer, Thuan V. Ly, Safdar N. Khan

Published in: European Journal of Orthopaedic Surgery & Traumatology | Issue 2/2019

Login to get access

Abstract

Objective

Delirium is one of the most common acute psychiatric disturbances taking place in patients, particularly elderly, following hip fractures. Using a validated national surgical database, we sought to define the incidence, risk factors and clinical impact associated with the occurrence of delirium following open reduction and internal fixation (ORIF) for hip fracture.

Methods

The 2016 American College of Surgeons—National Surgical Quality Improvement Program (ACS-NSQIP) Hip Fracture Targeted Procedure file—was retrieved and merged with the ACS-NSQIP 2016 file. A total of 7859 patients were finally included in the study.

Results

A total of 2177 (27.7%) patients experienced an episode of delirium following the procedure. Adjusted analysis showed an increasing age ≥ 65 years (p < 0.001), partially dependent functional health status prior to surgery (p = 0.001), bleeding disorder (p = 0.012), preoperative dementia (p < 0.001), preoperative delirium (p < 0.001), being bed-ridden postoperatively (p < 0.001), no weight bearing as tolerated on first postoperative day (p < 0.001), an ASA grade > II (p < 0.001), non-emergency case (p = 0.010) and a prolonged length of stay > 3 days (p < 0.001). In addition, Black or African-American ethnicity had a lower odds of developing postoperative delirium (p = 0.020) as compared to Whites. Moreover, postoperative delirium was significantly associated with non-home discharge disposition (p < 0.001), higher odds of 30-day readmissions (p < 0.001) and 30-day mortality (p < 0.001).

Conclusion

This study identifies several risk factors associated with the occurrence of postoperative delirium in patients undergoing ORIF for hip fracture. Surgeons can utilize these data to risk stratify and consequently tailor an appropriate preoperative and postoperative care protocol to prevent the occurrence of delirium.
Literature
1.
go back to reference Pietri M, Lucarini S (2007) The orthopaedic treatment of fragility fractures. Clin Cases Miner Bone Metab 4(2):108–116PubMedPubMedCentral Pietri M, Lucarini S (2007) The orthopaedic treatment of fragility fractures. Clin Cases Miner Bone Metab 4(2):108–116PubMedPubMedCentral
7.
go back to reference Brauer C, Morrison RS, Silberzweig SB, Siu AL (2000) The cause of delirium in patients with hip fracture. Arch Intern Med 160(12):1856–1860CrossRefPubMed Brauer C, Morrison RS, Silberzweig SB, Siu AL (2000) The cause of delirium in patients with hip fracture. Arch Intern Med 160(12):1856–1860CrossRefPubMed
8.
9.
go back to reference Kyziridis TC (2006) Post-operative delirium after hip fracture treatment: a review of the current literature. Psychosoc Med 3:Doc01PubMedPubMedCentral Kyziridis TC (2006) Post-operative delirium after hip fracture treatment: a review of the current literature. Psychosoc Med 3:Doc01PubMedPubMedCentral
10.
go back to reference Edlund A, Lundstrom M, Brannstrom B, Bucht G, Gustafson Y (2001) Delirium before and after operation for femoral neck fracture. J Am Geriatr Soc 49(10):1335–1340CrossRefPubMed Edlund A, Lundstrom M, Brannstrom B, Bucht G, Gustafson Y (2001) Delirium before and after operation for femoral neck fracture. J Am Geriatr Soc 49(10):1335–1340CrossRefPubMed
15.
go back to reference Edelstein DM, Aharonoff GB, Karp A, Capla EL, Zuckerman JD, Koval KJ (2004) Effect of postoperative delirium on outcome after hip fracture. Clin Orthop Relat Res 422:195–200CrossRef Edelstein DM, Aharonoff GB, Karp A, Capla EL, Zuckerman JD, Koval KJ (2004) Effect of postoperative delirium on outcome after hip fracture. Clin Orthop Relat Res 422:195–200CrossRef
33.
37.
go back to reference Morrison RS, Magaziner J, Gilbert M, Koval KJ, McLaughlin MA, Orosz G, Strauss E, Siu AL (2003) Relationship between pain and opioid analgesics on the development of delirium following hip fracture. J Gerontol A Biol Sci Med Sci 58(1):76–81CrossRefPubMed Morrison RS, Magaziner J, Gilbert M, Koval KJ, McLaughlin MA, Orosz G, Strauss E, Siu AL (2003) Relationship between pain and opioid analgesics on the development of delirium following hip fracture. J Gerontol A Biol Sci Med Sci 58(1):76–81CrossRefPubMed
38.
go back to reference Andersson EM, Gustafson L, Hallberg IR (2001) Acute confusional state in elderly orthopaedic patients: factors of importance for detection in nursing care. Int J Geriatr Psychiatry 16(1):7–17CrossRefPubMed Andersson EM, Gustafson L, Hallberg IR (2001) Acute confusional state in elderly orthopaedic patients: factors of importance for detection in nursing care. Int J Geriatr Psychiatry 16(1):7–17CrossRefPubMed
43.
Metadata
Title
Incidence, risk factors and clinical impact of postoperative delirium following open reduction and internal fixation (ORIF) for hip fractures: an analysis of 7859 patients from the ACS-NSQIP hip fracture procedure targeted database
Authors
Azeem Tariq Malik
Carmen E. Quatman
Laura S. Phieffer
Thuan V. Ly
Safdar N. Khan
Publication date
01-02-2019
Publisher
Springer Paris
Published in
European Journal of Orthopaedic Surgery & Traumatology / Issue 2/2019
Print ISSN: 1633-8065
Electronic ISSN: 1432-1068
DOI
https://doi.org/10.1007/s00590-018-2308-6

Other articles of this Issue 2/2019

European Journal of Orthopaedic Surgery & Traumatology 2/2019 Go to the issue

General Review • GENERAL ORTHOPAEDICS - MICROSURGERY

The history of microsurgery

General Review • UPPER LIMB - LOWER LIMB

Current concepts in peripheral nerve surgery