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Published in: European Spine Journal 9/2016

01-09-2016 | Original Article

Effect of depression and neuropathic pain using questionnaires on quality of life in patients with low back pain; cross-sectional retrospective study

Authors: Akihiko Hiyama, Masahiko Watanabe, Hiroyuki Katoh, Masato Sato, Daisuke Sakai, Joji Mochida

Published in: European Spine Journal | Issue 9/2016

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Abstract

Purpose

The present study investigated the percentage of low back pain (LBP) patients who have depressive symptoms and neuropathic pain and analyzed the effects of these on the quality of life (QOL) in these patients.

Methods

Of the 650 new patients with LBP that visited the hospital between June 2012 and December 2013, 309 patients who completed questionnaires to assess LBP and QOL were included in the study. The questionnaire included demographic items, the self-rated depression scale (SDS)-Zung, the Japanese version of the PainDETECT questionnaire (PDQ-J), numerical pain rating scale (NRS), and QOL assessments. The patients were divided into two groups according to their SDS-Zung scores: a nondepressed group with SDS scores <40 and a depressed group with SDS-Zung scores ≥50.

Results

One hundred twenty-five patients (40.5 %) were classified as nondepressed and 63 (20.4 %) as depressed. The mean PDQ-J score was higher in depressed patients than in nondepressed patients. The frequency of neuropathic pain was greater in depressed patients, with neuropathic pain observed in 17 of the 63 (27 %) depressed LBP patients and 11 of the 125 (9 %) nondepressed LBP patients. The SDS-Zung and PDQ-J scores of LBP patients were correlated significantly (r = 0.261, p < 0.001). Depressed patients had higher pain NRS scores and lower QOL scores compared with nondepressed patients.

Conclusions

Both the depressed patients and those with neuropathic LBP had a higher level of pain, greater pain-related disability, and poorer QOL compared with nondepressed patients. This is the first study to use the SDS-Zung and PDQ-J screening questionnaires to estimate the presence of neuropathic pain associated with depressive symptoms in LBP patients and to evaluate the impact of these on QOL.
Literature
2.
go back to reference Palacios-Cena D, Alonso-Blanco C, Hernandez-Barrera V, Carrasco-Garrido P, Jimenez-Garcia R, Fernandez-de-las-Penas C (2015) Prevalence of neck and low back pain in community-dwelling adults in Spain: an updated population-based national study (2009/10-2011/12). Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 24:482–492. doi:10.1007/s00586-014-3567-5 CrossRef Palacios-Cena D, Alonso-Blanco C, Hernandez-Barrera V, Carrasco-Garrido P, Jimenez-Garcia R, Fernandez-de-las-Penas C (2015) Prevalence of neck and low back pain in community-dwelling adults in Spain: an updated population-based national study (2009/10-2011/12). Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 24:482–492. doi:10.​1007/​s00586-014-3567-5 CrossRef
3.
go back to reference Cassidy JD, Carroll LJ, Cote P (1998) The Saskatchewan health and back pain survey. The prevalence of low back pain and related disability in Saskatchewan adults. Spine 23:1860–1866 (discussion 1867) CrossRefPubMed Cassidy JD, Carroll LJ, Cote P (1998) The Saskatchewan health and back pain survey. The prevalence of low back pain and related disability in Saskatchewan adults. Spine 23:1860–1866 (discussion 1867) CrossRefPubMed
5.
go back to reference Goucke CR (2003) The management of persistent pain. Med J Aust 178:444–447PubMed Goucke CR (2003) The management of persistent pain. Med J Aust 178:444–447PubMed
9.
go back to reference Bennett M (2001) The LANSS pain scale: the Leeds assessment of neuropathic symptoms and signs. Pain 92:147–157CrossRefPubMed Bennett M (2001) The LANSS pain scale: the Leeds assessment of neuropathic symptoms and signs. Pain 92:147–157CrossRefPubMed
10.
go back to reference Bouhassira D, Attal N, Alchaar H, Boureau F, Brochet B, Bruxelle J, Cunin G, Fermanian J, Ginies P, Grun-Overdyking A, Jafari-Schluep H, Lanteri-Minet M, Laurent B, Mick G, Serrie A, Valade D, Vicaut E (2005) Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4). Pain 114:29–36. doi:10.1016/j.pain.2004.12.010 CrossRefPubMed Bouhassira D, Attal N, Alchaar H, Boureau F, Brochet B, Bruxelle J, Cunin G, Fermanian J, Ginies P, Grun-Overdyking A, Jafari-Schluep H, Lanteri-Minet M, Laurent B, Mick G, Serrie A, Valade D, Vicaut E (2005) Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4). Pain 114:29–36. doi:10.​1016/​j.​pain.​2004.​12.​010 CrossRefPubMed
11.
go back to reference Fukuhara S, Bito S, Green J, Hsiao A, Kurokawa K (1998) Translation, adaptation, and validation of the SF-36 Health Survey for use in Japan. J Clin Epidemiol 51:1037–1044CrossRefPubMed Fukuhara S, Bito S, Green J, Hsiao A, Kurokawa K (1998) Translation, adaptation, and validation of the SF-36 Health Survey for use in Japan. J Clin Epidemiol 51:1037–1044CrossRefPubMed
12.
go back to reference Fukui M, Chiba K, Kawakami M, Kikuchi S, Konno S, Miyamoto M, Seichi A, Shimamura T, Shirado O, Taguchi T, Takahashi K, Takeshita K, Tani T, Toyama Y, Yonenobu K, Wada E, Tanaka T, Hirota Y, Subcommittee of the Clinical Outcome Committee of the Japanese Orthopaedic Association on Low Back P, Cervical Myelopathy E (2009) JOA back pain evaluation questionnaire (JOABPEQ)/JOA cervical myelopathy evaluation questionnaire (JOACMEQ). The report on the development of revised versions. April 16, 2007 The Subcommittee of the Clinical Outcome Committee of the Japanese Orthopaedic Association on low back pain and cervical myelopathy evaluation. J Orthop Sci Off J Jpn Orthop Assoc 14:348–365 Fukui M, Chiba K, Kawakami M, Kikuchi S, Konno S, Miyamoto M, Seichi A, Shimamura T, Shirado O, Taguchi T, Takahashi K, Takeshita K, Tani T, Toyama Y, Yonenobu K, Wada E, Tanaka T, Hirota Y, Subcommittee of the Clinical Outcome Committee of the Japanese Orthopaedic Association on Low Back P, Cervical Myelopathy E (2009) JOA back pain evaluation questionnaire (JOABPEQ)/JOA cervical myelopathy evaluation questionnaire (JOACMEQ). The report on the development of revised versions. April 16, 2007 The Subcommittee of the Clinical Outcome Committee of the Japanese Orthopaedic Association on low back pain and cervical myelopathy evaluation. J Orthop Sci Off J Jpn Orthop Assoc 14:348–365
13.
go back to reference Muzik M, Klier CM, Rosenblum KL, Holzinger A, Umek W, Katschnig H (2000) Are commonly used self-report inventories suitable for screening postpartum depression and anxiety disorders? Acta Psychiatr Scand 102:71–73CrossRefPubMed Muzik M, Klier CM, Rosenblum KL, Holzinger A, Umek W, Katschnig H (2000) Are commonly used self-report inventories suitable for screening postpartum depression and anxiety disorders? Acta Psychiatr Scand 102:71–73CrossRefPubMed
15.
go back to reference Biggs JT, Wylie LT, Ziegler VE (1978) Validity of the Zung self-rating depression scale. Br J Psychiatr J Ment Sci 132:381–385CrossRef Biggs JT, Wylie LT, Ziegler VE (1978) Validity of the Zung self-rating depression scale. Br J Psychiatr J Ment Sci 132:381–385CrossRef
16.
go back to reference Gabrys JB, Peters K (1985) Reliability, discriminant and predictive validity of the Zung self-rating depression scale. Psychol Rep 57:1091–1096CrossRefPubMed Gabrys JB, Peters K (1985) Reliability, discriminant and predictive validity of the Zung self-rating depression scale. Psychol Rep 57:1091–1096CrossRefPubMed
17.
go back to reference Fukuda K, Kobayashi S (1973) A study on a self-rating depression scale (author’s transl). Seishin Shinkeigaku Zasshi Psychiatr Neurol Jpn 75:673–679 Fukuda K, Kobayashi S (1973) A study on a self-rating depression scale (author’s transl). Seishin Shinkeigaku Zasshi Psychiatr Neurol Jpn 75:673–679
18.
go back to reference Faul F, Erdfelder E, Lang AG, Buchner A (2007) G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39:175–191CrossRefPubMed Faul F, Erdfelder E, Lang AG, Buchner A (2007) G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39:175–191CrossRefPubMed
21.
go back to reference Cedraschi C, Marty M, Courvoisier DS, Foltz V, Mahieu G, Demoulin C, Gierasimowicz Fontana A, Norberg M, de Goumoens P, Rozenberg S, Genevay S, Section Rachis de la Societe Francaise de R (2015) Core Outcome Measure Index for low back patients: do we miss anxiety and depression? Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc. doi:10.1007/s00586-015-3935-9 Cedraschi C, Marty M, Courvoisier DS, Foltz V, Mahieu G, Demoulin C, Gierasimowicz Fontana A, Norberg M, de Goumoens P, Rozenberg S, Genevay S, Section Rachis de la Societe Francaise de R (2015) Core Outcome Measure Index for low back patients: do we miss anxiety and depression? Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc. doi:10.​1007/​s00586-015-3935-9
22.
go back to reference Deyo RA, Battie M, Beurskens AJ, Bombardier C, Croft P, Koes B, Malmivaara A, Roland M, Von Korff M, Waddell G (1998) Outcome measures for low back pain research. A proposal for standardized use. Spine 23:2003–2013CrossRefPubMed Deyo RA, Battie M, Beurskens AJ, Bombardier C, Croft P, Koes B, Malmivaara A, Roland M, Von Korff M, Waddell G (1998) Outcome measures for low back pain research. A proposal for standardized use. Spine 23:2003–2013CrossRefPubMed
23.
go back to reference Gregory RJ (1994) The Zung self-rating depression scale as a potential screening tool for use with Eskimos. Hosp Commun Psychiatry 45:573–575 Gregory RJ (1994) The Zung self-rating depression scale as a potential screening tool for use with Eskimos. Hosp Commun Psychiatry 45:573–575
24.
go back to reference Hiyama A, Watanabe M, Katoh H, Sato M, Sakai D, Mochida J (2015) Evaluation of quality of life and neuropathic pain in patients with low back pain using the Japanese Orthopedic Association Back Pain Evaluation Questionnaire. Eur Spine J 24:503–512. doi:10.1007/s00586-014-3723-y CrossRefPubMed Hiyama A, Watanabe M, Katoh H, Sato M, Sakai D, Mochida J (2015) Evaluation of quality of life and neuropathic pain in patients with low back pain using the Japanese Orthopedic Association Back Pain Evaluation Questionnaire. Eur Spine J 24:503–512. doi:10.​1007/​s00586-014-3723-y CrossRefPubMed
26.
go back to reference El Sissi W, Arnaout A, Chaarani MW, Fouad M, El Assuity W, Zalzala M, Dershaby YE, Youseif E (2010) Prevalence of neuropathic pain among patients with chronic low-back pain in the Arabian Gulf Region assessed using the LEEDS assessment of neuropathic symptoms and signs pain scale. J Int Med Res 38:2135–2145CrossRefPubMed El Sissi W, Arnaout A, Chaarani MW, Fouad M, El Assuity W, Zalzala M, Dershaby YE, Youseif E (2010) Prevalence of neuropathic pain among patients with chronic low-back pain in the Arabian Gulf Region assessed using the LEEDS assessment of neuropathic symptoms and signs pain scale. J Int Med Res 38:2135–2145CrossRefPubMed
28.
go back to reference Schaefer C, Mann R, Sadosky A, Daniel S, Parsons B, Nieshoff E, Tuchman M, Nalamachu S, Anschel A, Stacey BR (2014) Burden of illness associated with peripheral and central neuropathic pain among adults seeking treatment in the United States: a patient-centered evaluation. Pain Med 15:2105–2119. doi:10.1111/pme.12502 CrossRefPubMedPubMedCentral Schaefer C, Mann R, Sadosky A, Daniel S, Parsons B, Nieshoff E, Tuchman M, Nalamachu S, Anschel A, Stacey BR (2014) Burden of illness associated with peripheral and central neuropathic pain among adults seeking treatment in the United States: a patient-centered evaluation. Pain Med 15:2105–2119. doi:10.​1111/​pme.​12502 CrossRefPubMedPubMedCentral
29.
go back to reference Pinheiro MB, Ferreira ML, Refshauge K, Ordonana JR, Machado GC, Prado LR, Maher CG, Ferreira PH (2015) Symptoms of depression and risk of new episodes of low back pain: a systematic review and meta-analysis. Arthr Care Res 67:1591–1603. doi:10.1002/acr.22619 CrossRef Pinheiro MB, Ferreira ML, Refshauge K, Ordonana JR, Machado GC, Prado LR, Maher CG, Ferreira PH (2015) Symptoms of depression and risk of new episodes of low back pain: a systematic review and meta-analysis. Arthr Care Res 67:1591–1603. doi:10.​1002/​acr.​22619 CrossRef
30.
go back to reference Carley JA, Karp JF, Gentili A, Marcum ZA, Reid MC, Rodriguez E, Rossi MI, Shega J, Thielke S, Weiner DK (2015) Deconstructing chronic low back pain in the older adult: step by step evidence and expert-based recommendations for evaluation and treatment: Part IV: Depression. pain medicine (Malden, Mass). doi: 10.1111/pme.12935 Carley JA, Karp JF, Gentili A, Marcum ZA, Reid MC, Rodriguez E, Rossi MI, Shega J, Thielke S, Weiner DK (2015) Deconstructing chronic low back pain in the older adult: step by step evidence and expert-based recommendations for evaluation and treatment: Part IV: Depression. pain medicine (Malden, Mass). doi: 10.​1111/​pme.​12935
33.
go back to reference Jensen MP, Barber J, Romano JM, Molton IR, Raichle KA, Osborne TL, Engel JM, Stoelb BL, Kraft GH, Patterson DR (2009) A comparison of self-hypnosis versus progressive muscle relaxation in patients with multiple sclerosis and chronic pain. Int J Clin Exp Hypn 57:198–221. doi:10.1080/00207140802665476 CrossRefPubMedPubMedCentral Jensen MP, Barber J, Romano JM, Molton IR, Raichle KA, Osborne TL, Engel JM, Stoelb BL, Kraft GH, Patterson DR (2009) A comparison of self-hypnosis versus progressive muscle relaxation in patients with multiple sclerosis and chronic pain. Int J Clin Exp Hypn 57:198–221. doi:10.​1080/​0020714080266547​6 CrossRefPubMedPubMedCentral
34.
go back to reference Havakeshian S, Mannion AF (2013) Negative beliefs and psychological disturbance in spine surgery patients: a cause or consequence of a poor treatment outcome? Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 22:2827–2835. doi:10.1007/s00586-013-2822-5 CrossRef Havakeshian S, Mannion AF (2013) Negative beliefs and psychological disturbance in spine surgery patients: a cause or consequence of a poor treatment outcome? Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 22:2827–2835. doi:10.​1007/​s00586-013-2822-5 CrossRef
35.
go back to reference Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J (1961) An inventory for measuring depression. Arch Gen Psychiatry 4:561–571CrossRefPubMed Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J (1961) An inventory for measuring depression. Arch Gen Psychiatry 4:561–571CrossRefPubMed
Metadata
Title
Effect of depression and neuropathic pain using questionnaires on quality of life in patients with low back pain; cross-sectional retrospective study
Authors
Akihiko Hiyama
Masahiko Watanabe
Hiroyuki Katoh
Masato Sato
Daisuke Sakai
Joji Mochida
Publication date
01-09-2016
Publisher
Springer Berlin Heidelberg
Published in
European Spine Journal / Issue 9/2016
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-016-4432-5

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