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Published in: European Spine Journal 2/2015

01-02-2015 | Review Article

Idiopathic scoliosis and the vestibular system

Authors: Ammar H. Hawasli, Timothy E. Hullar, Ian G. Dorward

Published in: European Spine Journal | Issue 2/2015

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Abstract

Purpose

Despite its high prevalence, the etiology underlying idiopathic scoliosis remains unclear. Although initial scrutiny has focused on genetic, biochemical, biomechanical, nutritional and congenital causes, there is growing evidence that aberrations in the vestibular system may play a role in the etiology of scoliosis. In this article, we discuss putative mechanisms for adolescent idiopathic scoliosis and review the current evidence supporting a role for the vestibular system in adolescent idiopathic scoliosis.

Methods

A comprehensive search of the English literature was performed using PubMed (http://​www.​ncbi.​nlm.​nih.​gov/​pubmed). Research articles studying interactions between adolescent idiopathic scoliosis and the vestibular system were selected and evaluated for inclusion in a literature review.

Results

Eighteen manuscripts of level 3–4 clinical evidence to support an association between adolescent idiopathic scoliosis (AIS) and dysfunction of the vestibular system were identified. These studies include data from physiologic and morphologic studies in humans. Clinical data are supported by animal model studies to suggest a causative link between the vestibular system and AIS.

Conclusions

Clinical data and a limited number of animal model studies suggest a causative role of the vestibular system in AIS, although this association has not been reproduced in all studies.
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Metadata
Title
Idiopathic scoliosis and the vestibular system
Authors
Ammar H. Hawasli
Timothy E. Hullar
Ian G. Dorward
Publication date
01-02-2015
Publisher
Springer Berlin Heidelberg
Published in
European Spine Journal / Issue 2/2015
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-014-3701-4

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