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European Spine Journal

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01-08-2013 | Original Article

Predisposing factors for surgical site infection of spinal instrumentation surgery for diabetes patients

Authors: Kotaro Satake, Tokumi Kanemura, Akiyuki Matsumoto, Hidetoshi Yamaguchi, Yoshimoto Ishikawa

Published in: European Spine Journal | Issue 8/2013

Abstract

Purpose

Diabetes mellitus (DM) is known as an important risk factor for surgical site infection (SSI) in spine surgery. It is still unclear however which DM-related parameters have stronger influence on SSI. The purpose of this study is to determine predisposing factors for SSI following spinal instrumentation surgery for patients with DM.

Methods

110 DM patients (66 males and 44 females) who underwent spinal instrumentation surgery in one institute were enrolled in this study. For each patient, various preoperative or intraoperative parameters were reviewed from medical records. Patients were divided into two groups (SSI or non-SSI) based on the postoperative course. Each parameter between these two groups was compared. Univariate and multivariate analyses were performed to determine predisposing factor for SSI.

Results

The SSI group consisted of 11 patients (10 %), and the non-SSI group of 99 patients (90 %). Univariate analysis revealed that preoperative proteinuria (p = 0.01), operation time (p = 0.04) and estimated blood loss (p = 0.02) were significantly higher in the SSI group compared to the non-SSI group. Multivariate logistic regression identified preoperative proteinuria as a statistically significant predictor of SSI (OR 6.28, 95 % CI 1.58–25.0, p = 0.009).

Conclusions

Proteinuria is a significant predisposing factor for SSI in spinal instrumentation surgery for DM patients. DM patients with proteinuria who are likely to suffer latent nephropathy have a potential risk for SSI. For them less invasive surgery is recommended for spinal instrumentation. In this retrospective study, there was no significant difference of preoperative condition in glycemic control between the two groups.

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Title: Predisposing factors for surgical site infection of spinal instrumentation surgery for diabetes patients
Authors: Kotaro Satake
Tokumi Kanemura
Akiyuki Matsumoto
Hidetoshi Yamaguchi
Yoshimoto Ishikawa
Publication date: 01-08-2013
Publisher: Springer Berlin Heidelberg
Published in: European Spine Journal / Issue 8/2013
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI: https://doi.org/10.1007/s00586-013-2783-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Predisposing factors for surgical site infection of spinal instrumentation surgery for diabetes patients

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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