Skip to main content
Top
Published in: European Spine Journal 1/2009

01-06-2009 | Original Article

Vertebroplasty and kyphoplasty: complementary techniques for the treatment of painful osteoporotic vertebral compression fractures. A prospective non-randomised study on 154 patients

Authors: Alessio Lovi, Marco Teli, Alessandro Ortolina, Francesco Costa, Maurizio Fornari, Marco Brayda-Bruno

Published in: European Spine Journal | Special Issue 1/2009

Login to get access

Abstract

In a prospective study, we aimed to evaluate the potential use of kyphoplasty (KP) and vertebroplasty (VP) as complementary techniques in the treatment of painful osteoporotic vertebral compression fractures (VCFs). After 1 month of conservative treatment for VCFs, patients with intractable pain were offered treatment with KP or VP according to a treatment algorithm that considers time from fracture (Δt) and amount of vertebral body collapse. Bone biopsy was obtained intra-operatively to exclude patients affected by malignancy or osteomalacia. 164 patients were included according to the above criteria. Mean age was 67.6 years. Mean follow-up was 33 months. 10 patients (6.1%) were lost to follow-up and 154 reached the minimum 2-year follow-up. 118 (69.5%) underwent VP and 36 (30.5%) underwent KP. Complications affected five patients treated with VP, whose one suffered a transient intercostal neuropathy and four a subsequent VCF (two at adjacent level). Results in terms of visual analogue scale and Oswestry scores were not different among treatment groups. In conclusion, at an average follow-up of almost 3 years from surgical treatment of osteoporotic VCFs, VP and KP show similar good clinical outcomes and appear to be complementary techniques with specific different indications.
Literature
1.
go back to reference Berlemann U, Franz T, Orler R et al (2004) Kyphoplasty for the treatment of osteoporotic vertebral fracture: a prospective non-randomized study. Eur Spine J 13:496–501PubMedCrossRef Berlemann U, Franz T, Orler R et al (2004) Kyphoplasty for the treatment of osteoporotic vertebral fracture: a prospective non-randomized study. Eur Spine J 13:496–501PubMedCrossRef
2.
go back to reference Brayda-Bruno M, Lovi A, Marinoni EC (2003) Vertebroplasty and kyphoplasty. Algorithm for the treatment of painful osteoporotic vertebral compression fractures. In: 10th International meeting on advanced spine techniques (IMAST). Rome, Italy, July 2003 Brayda-Bruno M, Lovi A, Marinoni EC (2003) Vertebroplasty and kyphoplasty. Algorithm for the treatment of painful osteoporotic vertebral compression fractures. In: 10th International meeting on advanced spine techniques (IMAST). Rome, Italy, July 2003
3.
go back to reference Cortet B, Cotten A, Boutry N et al (1999) Percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures: an open prospective study. J Rheumatol 26:2222–2228PubMed Cortet B, Cotten A, Boutry N et al (1999) Percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures: an open prospective study. J Rheumatol 26:2222–2228PubMed
4.
go back to reference Cyteval C, Sarrabere MP, Roux JO et al (1999) Acute osteoporotic vertebral collapse: open study on percutaneous injection of acrylic surgical cement in 20 patients. AJR Am J Roentgenol 173:1685–1690PubMed Cyteval C, Sarrabere MP, Roux JO et al (1999) Acute osteoporotic vertebral collapse: open study on percutaneous injection of acrylic surgical cement in 20 patients. AJR Am J Roentgenol 173:1685–1690PubMed
5.
go back to reference Deramond H, Depriester C, Galimbert P et al (1998) Percutaneous vertebroplasty with polymethylmethacrylate technique, indications and results. Radiol Clin North Am 36:533–546PubMedCrossRef Deramond H, Depriester C, Galimbert P et al (1998) Percutaneous vertebroplasty with polymethylmethacrylate technique, indications and results. Radiol Clin North Am 36:533–546PubMedCrossRef
6.
go back to reference Franck H, Boszczyk BM, Bierschneider M et al (2003) Interdisciplinary approach to balloon kyphoplasty in the treatment of osteoporotic vertebral compression fractures. Eur Spine J 12:S163–S167PubMedCrossRef Franck H, Boszczyk BM, Bierschneider M et al (2003) Interdisciplinary approach to balloon kyphoplasty in the treatment of osteoporotic vertebral compression fractures. Eur Spine J 12:S163–S167PubMedCrossRef
7.
go back to reference Garfin SR, Yuan HA, Reilley MA (2001) Kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine 26(14):1511–1555PubMedCrossRef Garfin SR, Yuan HA, Reilley MA (2001) Kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine 26(14):1511–1555PubMedCrossRef
8.
go back to reference Grohs JG, Matzner M, Trieb K et al (2005) Minimal invasive stabilization of osteoporotic vertebral fractures: a prospective nonrandomized comparison of vertebroplasty and balloon kyphoplasty. J Spinal Disord Tech 18:238–242PubMed Grohs JG, Matzner M, Trieb K et al (2005) Minimal invasive stabilization of osteoporotic vertebral fractures: a prospective nonrandomized comparison of vertebroplasty and balloon kyphoplasty. J Spinal Disord Tech 18:238–242PubMed
9.
go back to reference Hall SE, Criddle RA, Comito TL et al (1999) A case-control study of quality of life and functional impairment in women with long-standing vertebral osteoporotic fracture. Osteoporos Int 9(6):508–515PubMedCrossRef Hall SE, Criddle RA, Comito TL et al (1999) A case-control study of quality of life and functional impairment in women with long-standing vertebral osteoporotic fracture. Osteoporos Int 9(6):508–515PubMedCrossRef
10.
go back to reference Hardouin P, Fayada P, Leclet H et al (2002) Kyphoplasty. J Bone Spine 69(3):256–261CrossRef Hardouin P, Fayada P, Leclet H et al (2002) Kyphoplasty. J Bone Spine 69(3):256–261CrossRef
11.
go back to reference Heini PF, Orler R (2004) Kyphoplasty for treatment of osteoporotic vertebral fractures. Eur Spine J 13(3):184–192PubMedCrossRef Heini PF, Orler R (2004) Kyphoplasty for treatment of osteoporotic vertebral fractures. Eur Spine J 13(3):184–192PubMedCrossRef
12.
go back to reference Heini PF, Walchli B, Berleman U (2000) Percutaneous transpedicular vertebroplasty with PMMA: operative technique and early results. A prospective study for the treatment of osteoporotic compression fracture. Eur Spine J 9:445–450PubMedCrossRef Heini PF, Walchli B, Berleman U (2000) Percutaneous transpedicular vertebroplasty with PMMA: operative technique and early results. A prospective study for the treatment of osteoporotic compression fracture. Eur Spine J 9:445–450PubMedCrossRef
13.
go back to reference Hulme PA, Krebs J, Ferguson SJ, Berlemann U (2006) Vertebroplasty and kyphoplasty: a systematic review of 69 clinical studies. Spine 31(17):1983–2001PubMedCrossRef Hulme PA, Krebs J, Ferguson SJ, Berlemann U (2006) Vertebroplasty and kyphoplasty: a systematic review of 69 clinical studies. Spine 31(17):1983–2001PubMedCrossRef
14.
go back to reference Kasperk C, Hillmeier J, Noldge G et al (2005) Treatment of painful vertebral fractures by kyphoplasty in patients with primary osteoporosis: a prospective nonrandomized controlled study. J Bone Miner Res 20(4):604–612PubMedCrossRef Kasperk C, Hillmeier J, Noldge G et al (2005) Treatment of painful vertebral fractures by kyphoplasty in patients with primary osteoporosis: a prospective nonrandomized controlled study. J Bone Miner Res 20(4):604–612PubMedCrossRef
15.
go back to reference Legroux-Gerot I, Lormeau C, Boutry N et al (2004) Long-term follow-up of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. Clin Rheumatol 23(4):310–317PubMedCrossRef Legroux-Gerot I, Lormeau C, Boutry N et al (2004) Long-term follow-up of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. Clin Rheumatol 23(4):310–317PubMedCrossRef
16.
go back to reference Leidig-Bruckner G, Minne HW et al (1997) Clinical grading of spinal osteoporosis: quality of life components and spinal deformity in women with chronic low back pain and women with vertebral osteoporosis. J Bone Miner Res 12(4):663–675PubMedCrossRef Leidig-Bruckner G, Minne HW et al (1997) Clinical grading of spinal osteoporosis: quality of life components and spinal deformity in women with chronic low back pain and women with vertebral osteoporosis. J Bone Miner Res 12(4):663–675PubMedCrossRef
17.
go back to reference Levine SA, Perin LA, Hayes D et al (2000) An evidence-based evaluation of percutaneous vertebroplasty. Manage Care 9:56–63 Levine SA, Perin LA, Hayes D et al (2000) An evidence-based evaluation of percutaneous vertebroplasty. Manage Care 9:56–63
18.
go back to reference Lieberman IH, Dudeney S, Reinhardt MK et al (2001) Initial outcome and efficacy of “kyphoplasty” in the treatment of painful osteoporotic vertebral compression fractures. Spine 26(14):1631–1638PubMedCrossRef Lieberman IH, Dudeney S, Reinhardt MK et al (2001) Initial outcome and efficacy of “kyphoplasty” in the treatment of painful osteoporotic vertebral compression fractures. Spine 26(14):1631–1638PubMedCrossRef
19.
go back to reference Mathis JM, Orlando Ortiz A, Zoarski G (2004) Vertebroplasty versus Kyphoplasty: a comparison and contrast. Am J Neuroradiol 25:840–845PubMed Mathis JM, Orlando Ortiz A, Zoarski G (2004) Vertebroplasty versus Kyphoplasty: a comparison and contrast. Am J Neuroradiol 25:840–845PubMed
20.
go back to reference Matthis C, Weber U, O’Neill TW et al (1998) Health impact associated with vertebral deformities: results from the European Vertebral Osteoporosis Study (EVOS). Osteoporos Int 8(4):364–372PubMedCrossRef Matthis C, Weber U, O’Neill TW et al (1998) Health impact associated with vertebral deformities: results from the European Vertebral Osteoporosis Study (EVOS). Osteoporos Int 8(4):364–372PubMedCrossRef
21.
go back to reference Mc Kiernan F, Faciszewski T, Jensen R (2003) Reporting height restoration in vertebral compression fractures. Spine 28(22):2517–2521 Mc Kiernan F, Faciszewski T, Jensen R (2003) Reporting height restoration in vertebral compression fractures. Spine 28(22):2517–2521
22.
go back to reference Mehbod A, Aunoble S, Le Huec JC (2003) Vertebroplasty for osteoporotic spine fracture: prevention and treatment. Eur Spine J 12:S155–S162PubMedCrossRef Mehbod A, Aunoble S, Le Huec JC (2003) Vertebroplasty for osteoporotic spine fracture: prevention and treatment. Eur Spine J 12:S155–S162PubMedCrossRef
23.
go back to reference Phillips FM (2003) Minimally invasive treatments of osteoporotic vertebral compression fractures. Spine 15S:S45–S53CrossRef Phillips FM (2003) Minimally invasive treatments of osteoporotic vertebral compression fractures. Spine 15S:S45–S53CrossRef
24.
go back to reference Phillips FM, Todd Wetzel F, Lieberman I et al (2002) An in vivo comparison of the potential for extravertebral cement leak after vertebroplasty and kyphoplasty. Spine 27(19):2173–2178PubMedCrossRef Phillips FM, Todd Wetzel F, Lieberman I et al (2002) An in vivo comparison of the potential for extravertebral cement leak after vertebroplasty and kyphoplasty. Spine 27(19):2173–2178PubMedCrossRef
25.
go back to reference Pradhan BP, Hyun WB, Kropf MA et al (2006) Kyphoplasty reduction of Osteoporotic vertebral compression fractures: correction of local kyphosis versus overall sagittal alignment. Spine 31(4):435–441PubMedCrossRef Pradhan BP, Hyun WB, Kropf MA et al (2006) Kyphoplasty reduction of Osteoporotic vertebral compression fractures: correction of local kyphosis versus overall sagittal alignment. Spine 31(4):435–441PubMedCrossRef
26.
go back to reference Rao RD, Singrakhia MD (2003) Painful osteoporotic vertebral fracture. Pathogenesis, evaluation and roles of vertebroplasty and kyphoplasty in its management. J Bone Joint Surg 85-A(10):2010–2022 Rao RD, Singrakhia MD (2003) Painful osteoporotic vertebral fracture. Pathogenesis, evaluation and roles of vertebroplasty and kyphoplasty in its management. J Bone Joint Surg 85-A(10):2010–2022
27.
go back to reference Taylor RS, Taylor RJ, Fritzell P (2006) Balloon kyphoplasty and vertebroplasty for vertebral compression fractures. A comparative systematic review of efficacy and safety. Spine 31(23):2747–2755PubMedCrossRef Taylor RS, Taylor RJ, Fritzell P (2006) Balloon kyphoplasty and vertebroplasty for vertebral compression fractures. A comparative systematic review of efficacy and safety. Spine 31(23):2747–2755PubMedCrossRef
Metadata
Title
Vertebroplasty and kyphoplasty: complementary techniques for the treatment of painful osteoporotic vertebral compression fractures. A prospective non-randomised study on 154 patients
Authors
Alessio Lovi
Marco Teli
Alessandro Ortolina
Francesco Costa
Maurizio Fornari
Marco Brayda-Bruno
Publication date
01-06-2009
Publisher
Springer-Verlag
Published in
European Spine Journal / Issue Special Issue 1/2009
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-009-0986-9

Other articles of this Special Issue 1/2009

European Spine Journal 1/2009 Go to the issue