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Published in: European Spine Journal 3/2006

01-08-2006 | Review

Molecular therapy of the intervertebral disc

Authors: S. Tim Yoon, Nilpesh M. Patel

Published in: European Spine Journal | Special Issue 3/2006

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Abstract

Disc degeneration is the loss of the normal nucleus pulposus disc matrix to a more fibrotic and less cartilaginous structure. This change in disc micro-anatomy can be associated with pain and deformity, however, prevention and treatment options of disc degeneration are currently limited. Much research is going on to understand intervertebral discs at a molecular/ cellular level in hopes of creating clinically applicable options for treating disc degeneration. This review article will give insight into the current and developing status of treating intervertebral disc degeneration from a molecular standpoint.
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Metadata
Title
Molecular therapy of the intervertebral disc
Authors
S. Tim Yoon
Nilpesh M. Patel
Publication date
01-08-2006
Publisher
Springer-Verlag
Published in
European Spine Journal / Issue Special Issue 3/2006
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-006-0155-3

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