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Published in: Comparative Clinical Pathology 1/2018

01-01-2018 | Brief Communication

Pure red cell aplasia in a Holstein calf

Authors: Masaki Maezawa, Kenzi Koyama, Noriyuki Horiuchi, Yoshiyasu Kobayashi, Hisashi Inokuma

Published in: Comparative Clinical Pathology | Issue 1/2018

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Abstract

A 3-month-old Holstein calf presented with lethargy. Hematological examination showed severe non-regenerative anemia without reduction in white blood cell and platelet counts. Serum biochemical analysis revealed both high erythropoietin activity and high serum iron concentration. Bone marrow examination revealed selectively decreased erythroid precursors and an increased myeloid:erythroid ratio of 7:1. Lesions that could have caused anemia were found only in bone marrow by necropsy. The calf was diagnosed with pure red cell aplasia (PRCA) based on these clinical and pathological findings. Although the cause of PRCA was not identified, this is the first confirmed clinical report of PRCA in a Holstein calf.
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Metadata
Title
Pure red cell aplasia in a Holstein calf
Authors
Masaki Maezawa
Kenzi Koyama
Noriyuki Horiuchi
Yoshiyasu Kobayashi
Hisashi Inokuma
Publication date
01-01-2018
Publisher
Springer London
Published in
Comparative Clinical Pathology / Issue 1/2018
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI
https://doi.org/10.1007/s00580-017-2586-0

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