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01-05-2017 | Original Article

Evaluation of salivary level of IL-10 in patients with oral lichen planus, a preliminary investigation

Authors: Fahimeh Rezazadeh, Fariba Shahbazi, Azadeh Andisheh-Tadbir

Published in: Comparative Clinical Pathology | Issue 3/2017

Abstract

Oral lichen planus is an inflammatory disorder with T-cell-mediated immunological etiology. The aim of this study was to evaluate the IL-10 in saliva of OLP patients and compare it with healthy people. In this cross-sectional study, 44 patients with oral lichen planus and 44 healthy people were enrolled to the study. Five to 10 ml un-stimulated whole saliva samples were collected in the morning, and concentration of IL-10 was measured using enzyme-linked immunosorbent assay (ELISA). The mean of salivary IL-10 was more in the patient group (0.2 ± 0.92) than the healthy group (0.1 ± 0.04), but there was no significant difference between these groups. No significant relation was found between salivary IL-10 level and type of OLP. The result of present study showed no significant differences in salivary level of IL-10 between OLP and healthy people.

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Title: Evaluation of salivary level of IL-10 in patients with oral lichen planus, a preliminary investigation
Authors: Fahimeh Rezazadeh
Fariba Shahbazi
Azadeh Andisheh-Tadbir
Publication date: 01-05-2017
Publisher: Springer London
Published in: Comparative Clinical Pathology / Issue 3/2017
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI: https://doi.org/10.1007/s00580-017-2415-5

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Evaluation of salivary level of IL-10 in patients with oral lichen planus, a preliminary investigation

Abstract

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