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Published in: Comparative Clinical Pathology 3/2017

01-05-2017 | Case Report

Two foals with ectrodactyly in hindlimb: first report

Authors: Shahrzad Azizi, Morteza Kuhi, Reza Kheirandish, Amir Asadabadi, Vesal Abdoli

Published in: Comparative Clinical Pathology | Issue 3/2017

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Abstract

Ectrodactyly refers to the congenital absence of phalanges as total or partial. In the veterinary literature, ectrodactyly has been described in dogs and domestic cats as a rare congenital heterogeneous disorder. The current report has described unilateral ectrodactyly in the left hindlimb of two born foals in an area with presence of Iranit and zinc manufactures. One of the foals was lack of the third phalanx and the other one had not the third and second phalanxes. No other abnormality was found in these cases. Various teratogens may be responsible for occurring skeletal anomalies. To the best of our knowledge, the present study is the first report of ectrodactyly in horse.
Literature
go back to reference Aulthouse A, Hitt D (1994) The teratogenic effects of valproic acid in human chondrogenesis in vitro. Teratol 49(3):208–217CrossRef Aulthouse A, Hitt D (1994) The teratogenic effects of valproic acid in human chondrogenesis in vitro. Teratol 49(3):208–217CrossRef
go back to reference Carrig CB, Wortman JA, Morris EL, Blevins WE, Root CR, Hanlon GF, Suter PF (1981) Ectrodactyly (split-hand deformity) in the dog. Vet Radiol Ultrasound 22:123–144CrossRef Carrig CB, Wortman JA, Morris EL, Blevins WE, Root CR, Hanlon GF, Suter PF (1981) Ectrodactyly (split-hand deformity) in the dog. Vet Radiol Ultrasound 22:123–144CrossRef
go back to reference Carvallo FR, Domínguez AS, Morales PC (2010) Bilateral ectrodactyly and spinal deformation in a mixed-breed dog. Can Vet J 51:47–49 Carvallo FR, Domínguez AS, Morales PC (2010) Bilateral ectrodactyly and spinal deformation in a mixed-breed dog. Can Vet J 51:47–49
go back to reference Chen H, Boontheung P, Loo RR, Xie Y, Loo JA, Rao JY, Collins MD (2008) Proteomic analysis to characterize differential mouse strain sensitivity to cadmium-induced forelimb teratogenesis. Birth Defects Res A Clin Mol Teratolo 82(4):187–199CrossRef Chen H, Boontheung P, Loo RR, Xie Y, Loo JA, Rao JY, Collins MD (2008) Proteomic analysis to characterize differential mouse strain sensitivity to cadmium-induced forelimb teratogenesis. Birth Defects Res A Clin Mol Teratolo 82(4):187–199CrossRef
go back to reference Collins M, Walling K, Resnick E, Scott W (1991) The effect of administration time on malformations induced by three anticonvulsant agents in C57BL/6J mice with emphasis on forelimb ectrodactyly. Teratology 44(6):617–628CrossRefPubMed Collins M, Walling K, Resnick E, Scott W (1991) The effect of administration time on malformations induced by three anticonvulsant agents in C57BL/6J mice with emphasis on forelimb ectrodactyly. Teratology 44(6):617–628CrossRefPubMed
go back to reference Cooper JE, Purton P, Poswillo DE (1990) A lobster claw abnormality in the common marmoset (Callithrix jacchus). Lab Anim 24:151–155CrossRefPubMed Cooper JE, Purton P, Poswillo DE (1990) A lobster claw abnormality in the common marmoset (Callithrix jacchus). Lab Anim 24:151–155CrossRefPubMed
go back to reference Ferreira MP, Alievi MM, Beck CAC, Voll J, Muccillo MS, Gomes C (2007) Ectrodactyly in dog: case report. Arq Bras Med Vet Zootec 59:910–913CrossRef Ferreira MP, Alievi MM, Beck CAC, Voll J, Muccillo MS, Gomes C (2007) Ectrodactyly in dog: case report. Arq Bras Med Vet Zootec 59:910–913CrossRef
go back to reference Innes JF, McKee WM, Mitchell RAS, Lascelles BDX, Johnson KA (2001) Surgical reconstruction of ectrodactyly deformity in four dogs. Vet Comp Orthop Traumatol 14:201–209 Innes JF, McKee WM, Mitchell RAS, Lascelles BDX, Johnson KA (2001) Surgical reconstruction of ectrodactyly deformity in four dogs. Vet Comp Orthop Traumatol 14:201–209
go back to reference Jubb KVF, Kennedy CP (2007) Pathology of domestic animal, 4th edn. Academic Press, New York Jubb KVF, Kennedy CP (2007) Pathology of domestic animal, 4th edn. Academic Press, New York
go back to reference Kenneth AJ (2010) Skeletal disease. In: Ettinger SJ, Feldman EC (eds) Textbook of veterinary internal medicine, 7th edn. W.B. Saunders, Philadelphia Kenneth AJ (2010) Skeletal disease. In: Ettinger SJ, Feldman EC (eds) Textbook of veterinary internal medicine, 7th edn. W.B. Saunders, Philadelphia
go back to reference Menke LA, Bijlsma EK, Van Essen AJ, van den Boogaard MJ, van Rijn RR, Cobben JM (2008) Ectrodactyly with fibular aplasia: a separate entity? Eur J Med Genet 51(5):488–496CrossRefPubMed Menke LA, Bijlsma EK, Van Essen AJ, van den Boogaard MJ, van Rijn RR, Cobben JM (2008) Ectrodactyly with fibular aplasia: a separate entity? Eur J Med Genet 51(5):488–496CrossRefPubMed
go back to reference Montgomery M, Tomlinson J (1985) Two cases of ectrodactyly and congenital elbow luxations in the dog. J Am Anim Hosp Assoc 21:781–785 Montgomery M, Tomlinson J (1985) Two cases of ectrodactyly and congenital elbow luxations in the dog. J Am Anim Hosp Assoc 21:781–785
go back to reference Ogino T (2007) Clinical features and teratogenic mechanisms of congenital absence of digits. Develop Growth Differ 49:523–531CrossRef Ogino T (2007) Clinical features and teratogenic mechanisms of congenital absence of digits. Develop Growth Differ 49:523–531CrossRef
go back to reference Pratschke K (1996) A case of ectrodactyly in a dog. Irish Vet J 49:412–413 Pratschke K (1996) A case of ectrodactyly in a dog. Irish Vet J 49:412–413
go back to reference Ramadan RO (1993) Hemimelia and ectrodactyly in a Najdi sheep. Agri-Practice 14:30–32 Ramadan RO (1993) Hemimelia and ectrodactyly in a Najdi sheep. Agri-Practice 14:30–32
go back to reference Sanders D, Stevens T (1991) Review of drug induced limb defects in mammals. Teratol 44:335–354CrossRef Sanders D, Stevens T (1991) Review of drug induced limb defects in mammals. Teratol 44:335–354CrossRef
go back to reference Schneck GW (1974) Two cases of congenital malformation (peromelus ascelus and ectrodactyly) in cats. Vet Med Small Anim Clin 69:1025–1026PubMed Schneck GW (1974) Two cases of congenital malformation (peromelus ascelus and ectrodactyly) in cats. Vet Med Small Anim Clin 69:1025–1026PubMed
go back to reference Searle A (1953) Hereditary split-hand in the domestic cat. Ann Eugenics 17:279–282CrossRef Searle A (1953) Hereditary split-hand in the domestic cat. Ann Eugenics 17:279–282CrossRef
go back to reference Seto ML, Nunes ME, MacArthur CA, Cunningham ML (1997) Pathogenesis of ectrodactyly in the dactylaplasia mouse: aberrant cell death of the apical ectodermal ridge. Teratol 56:262–270CrossRef Seto ML, Nunes ME, MacArthur CA, Cunningham ML (1997) Pathogenesis of ectrodactyly in the dactylaplasia mouse: aberrant cell death of the apical ectodermal ridge. Teratol 56:262–270CrossRef
go back to reference Towle HAM, Breur GJ (2004) Dystoses of the canine and feline appendicular skeleton. J Am Vet Med Assoc 225:1685–1692CrossRefPubMed Towle HAM, Breur GJ (2004) Dystoses of the canine and feline appendicular skeleton. J Am Vet Med Assoc 225:1685–1692CrossRefPubMed
Metadata
Title
Two foals with ectrodactyly in hindlimb: first report
Authors
Shahrzad Azizi
Morteza Kuhi
Reza Kheirandish
Amir Asadabadi
Vesal Abdoli
Publication date
01-05-2017
Publisher
Springer London
Published in
Comparative Clinical Pathology / Issue 3/2017
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI
https://doi.org/10.1007/s00580-017-2408-4

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