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01-11-2015 | Original Article

Association between serum copper concentration and the risk of bovine leptospirosis

Authors: Elham Mohammadi, Ehsanollah Sakhaee

Published in: Comparative Clinical Pathology | Issue 6/2015

Abstract

Leptospirosis is a zoonotic disease found in nearly all parts of the world. This disease is exacerbated by a weakened immune system. Copper is an important component of the immune system. The aim of this study was to investigate the effect of copper deficiency on leptospirosis occurrence. A total of 260 serum samples were randomly collected from eight industrial and semi-industrial dairy farms from center and southeast of Iran. Microscopic agglutination test to check leptospirosis was performed. Serum copper level was analyzed using an atomic absorption spectrometer. Fifty-eight serum samples had detectable antibodies against at least one serovar of Leptospira interrogans at a dilution of ≥1:100, and among the positive cows, 55 samples were copper deficient. In contrast, there were 202 serologically negative subjects, 29 of these samples had copper deficiency. Copper deficiency can weaken immunity and thus exacerbate the incidence of leptospirosis.

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Title: Association between serum copper concentration and the risk of bovine leptospirosis
Authors: Elham Mohammadi
Ehsanollah Sakhaee
Publication date: 01-11-2015
Publisher: Springer London
Published in: Comparative Clinical Pathology / Issue 6/2015
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI: https://doi.org/10.1007/s00580-015-2069-0

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Association between serum copper concentration and the risk of bovine leptospirosis

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