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Journal of Anesthesia
Published in: Journal of Anesthesia 3/2015

01-06-2015 | Short Communication

Dexmedetomidine and ketamine combination for a patient with xeroderma pigmentosa

Authors: Rakhee Goyal, Mubashir Syed Islam

Published in: Journal of Anesthesia | Issue 3/2015

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Abstract

Patients of xeroderma pigmentosa (XP) have increased sensitivity to ultraviolet light and a defective nucleotide excision repair (NER) mechanism in their DNA. Several types of neurological, dermatological, and ophthalmological complications are common in these patients. There is increasing evidence of delayed recovery and worsening of neurological status following general anesthesia in such patients. Some reports have shown uneventful conduct of total intravenous anesthesia in patients of XP. The authors report a case of XP in a young girl for surgery, previously anesthetized with delayed recovery, managed successfully with a combination of intravenous dexmedetomidine and ketamine.
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Metadata
Title
Dexmedetomidine and ketamine combination for a patient with xeroderma pigmentosa
Authors
Rakhee Goyal
Mubashir Syed Islam
Publication date
01-06-2015
Publisher
Springer Japan
Published in
Journal of Anesthesia / Issue 3/2015
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-014-1928-1

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