Skip to main content
Top
Published in: Journal of Anesthesia 2/2012

01-04-2012 | Clinical Report

Propofol use for sedation or sedation for propofol use?

Author: Duk-Kyung Kim

Published in: Journal of Anesthesia | Issue 2/2012

Login to get access

Abstract

A large amount of pharmacological and clinical evidence supports the abuse potential of propofol. Although previous case reports have indicated that recreational use of propofol is primarily by medical professionals, its spread among the general public has recently been highlighted. This is the first case report to show that cravings for propofol can be quite intense in some people, and thus propofol can be wrongfully used by clinicians who are enticed by the promise of monetary gain. Illicit diversion of propofol in hospitals has been confirmed; thus, propofol has been designated as a controlled substance in South Korea as of February 2011.
Literature
1.
2.
go back to reference Kirby RR, Colaw JM, Douglas MM. Death from propofol: accident, suicide, or murder? Anesth Analg. 2009;108:1182–4.PubMedCrossRef Kirby RR, Colaw JM, Douglas MM. Death from propofol: accident, suicide, or murder? Anesth Analg. 2009;108:1182–4.PubMedCrossRef
3.
go back to reference Zancy JP, Lichtor JL, Thompson W, Apfelbaum JL. Propofol at a subanesthetic dose may have abuse potential in healthy volunteers. Anesth Analg. 1993;77:544–52. Zancy JP, Lichtor JL, Thompson W, Apfelbaum JL. Propofol at a subanesthetic dose may have abuse potential in healthy volunteers. Anesth Analg. 1993;77:544–52.
4.
go back to reference Kranioti EF, Mavroforou A, Mylonakis P, Michalodimitrakis M. Lethal self administration of propofol (Diprivan). A case report and review of the literature. Forensic Sci Int. 2007;167:56–8.PubMedCrossRef Kranioti EF, Mavroforou A, Mylonakis P, Michalodimitrakis M. Lethal self administration of propofol (Diprivan). A case report and review of the literature. Forensic Sci Int. 2007;167:56–8.PubMedCrossRef
5.
go back to reference Wischmeyer PE, Johnson BR, Wilson JE, Dingmann C, Bachman HM, Roller E, Tran ZV, Henthorn TK. A survey of propofol abuse in academic anesthesia programs. Anesth Analg. 2007;105:1066–71.PubMedCrossRef Wischmeyer PE, Johnson BR, Wilson JE, Dingmann C, Bachman HM, Roller E, Tran ZV, Henthorn TK. A survey of propofol abuse in academic anesthesia programs. Anesth Analg. 2007;105:1066–71.PubMedCrossRef
6.
go back to reference LeSage MG, Stafford D, Glowa JR. Abuse liability of the anesthetic propofol: self-administration of propofol in rats under fixed-ratio schedules of drug delivery. Psychopharmacology. 2000;153:148–54.PubMedCrossRef LeSage MG, Stafford D, Glowa JR. Abuse liability of the anesthetic propofol: self-administration of propofol in rats under fixed-ratio schedules of drug delivery. Psychopharmacology. 2000;153:148–54.PubMedCrossRef
7.
go back to reference Pain L, Oberling P, Sandner G, Di Scala G. Effect of propofol on affective state as assessed by place conditioning paradigm in rats. Anesthesiology. 1996;85:121–8.PubMedCrossRef Pain L, Oberling P, Sandner G, Di Scala G. Effect of propofol on affective state as assessed by place conditioning paradigm in rats. Anesthesiology. 1996;85:121–8.PubMedCrossRef
8.
9.
go back to reference Koopmann A, von der Goltz C, Hermann D, Kiefer F. Propofol addiction initiated by anesthetic use. Am J Psychiatry. 2011;168:211–2.PubMedCrossRef Koopmann A, von der Goltz C, Hermann D, Kiefer F. Propofol addiction initiated by anesthetic use. Am J Psychiatry. 2011;168:211–2.PubMedCrossRef
10.
go back to reference Schneider U, Rada D, Rollnik JD, Passie T, Emrich HM. Propofol dependency after treatment of tension headache. Addict Biol. 2001;6:263–5.PubMedCrossRef Schneider U, Rada D, Rollnik JD, Passie T, Emrich HM. Propofol dependency after treatment of tension headache. Addict Biol. 2001;6:263–5.PubMedCrossRef
Metadata
Title
Propofol use for sedation or sedation for propofol use?
Author
Duk-Kyung Kim
Publication date
01-04-2012
Publisher
Springer Japan
Published in
Journal of Anesthesia / Issue 2/2012
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-011-1275-4

Other articles of this Issue 2/2012

Journal of Anesthesia 2/2012 Go to the issue