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Journal of Anesthesia
Published in: Journal of Anesthesia 1/2011

01-02-2011 | Original Article

Preoperative depression is a risk factor for postoperative short-term and long-term cognitive dysfunction in patients with diabetes mellitus

Authors: Yuji Kadoi, Chikara Kawauchi, Masanobu Ide, Masataka Kuroda, Kenichiro Takahashi, Shigeru Saito, Nao Fujita, Akio Mizutani

Published in: Journal of Anesthesia | Issue 1/2011

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Abstract

Purpose

To identify whether the presence of preoperative depression in patients with diabetes mellitus is a risk factor for postoperative cognitive dysfunction after coronary artery bypass graft (CABG) surgery.

Methods

Data from 90 patients with diabetes mellitus undergoing elective CABG were analyzed. Hemodynamic data (arterial and jugular venous blood gas values) were measured during cardiopulmonary bypass. Preoperatively, all patients were given the 21-item Beck depression inventory to identify the presence of depression. In addition, all patients underwent a battery of neurological and neuropsychological tests the day before surgery, 7 days after surgery, and 6 months after surgery.

Results

The rate of cognitive dysfunction was 50% at 7 days and 23% at 6 months after surgery. Age, hypertension, presence of depression, duration of SjvO2 ≤ 50%, ascending aorta atherosclerosis, diabetic retinopathy, and insulin therapy were independent predictors of short-term cognitive dysfunction, whereas HbA1c, diabetic retinopathy, insulin therapy, and presence of depression were independent predictors of long-term cognitive dysfunction.

Conclusions

We found that the presence of depression preoperatively is associated with short-term and long-term postoperative cognitive dysfunction in patients with diabetes mellitus.
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Metadata
Title
Preoperative depression is a risk factor for postoperative short-term and long-term cognitive dysfunction in patients with diabetes mellitus
Authors
Yuji Kadoi
Chikara Kawauchi
Masanobu Ide
Masataka Kuroda
Kenichiro Takahashi
Shigeru Saito
Nao Fujita
Akio Mizutani
Publication date
01-02-2011
Publisher
Springer Japan
Published in
Journal of Anesthesia / Issue 1/2011
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-010-1072-5

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