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Supportive Care in Cancer

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01-07-2018 | Original Article

Predictors of enrollment in individual- and couple-based lifestyle intervention trials for cancer survivors

Authors: Emily Cox-Martin, Jaejoon Song, Wendy Demark-Wahnefried, Elizabeth J. Lyons, Karen Basen-Engquist

Published in: Supportive Care in Cancer | Issue 7/2018

Abstract

Purpose

To utilize data from lifestyle intervention pilot studies for cancer survivors to elucidate demographic, disease-related, and health behavior factors that might predict enrollment in this type of research. Additionally, factors were differentially compared based on intervention design (i.e., individual versus couple-based).

Methods

Secondary data analysis was conducted regarding predictors of enrollment into lifestyle intervention studies, including Healthy Moves Weight Loss (individual participants, screened n = 89, enrolled n = 30) and Healthy Moves Couples (survivors and their partners, screened n = 197, enrolled n = 23). Due to small sample sizes, common in pilot studies, random forest analyses were used to maximize information yielded by the data.

Results

Results identified numerous important predictors of enrollment in individual and couple-based lifestyle interventions. Percent energy from fat and physical activity minutes were identified as important predictors for both recruitment methods. Age, cancer site, and marital status were important predictors of enrollment in the individual-based intervention. Weight, fiber consumption, and disease-related symptom severity and interference were important predictors of enrollment in the couple-based intervention.

Conclusion

Although there was some overlap in predictors for enrollment between studies, many differential predictors were identified between individual versus couple-based study designs for lifestyle intervention in cancer survivors. Future lifestyle intervention studies for cancer survivors may benefit from targeting different predictors of enrollment based on study design to optimize recruitment. Additionally, understanding predictors may allow certain barriers to enrollment (i.e., symptom burden) to be directly addressed, making lifestyle intervention research more feasible and acceptable to difficult-to-recruit survivors.

Healthy Moves Weight Loss enrolled a total of 37 survivors, however, due to differences in recruitment methods, endometrial survivors from the parent study (n = 7), were not included in these analyses.

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Title: Predictors of enrollment in individual- and couple-based lifestyle intervention trials for cancer survivors
Authors: Emily Cox-Martin
Jaejoon Song
Wendy Demark-Wahnefried
Elizabeth J. Lyons
Karen Basen-Engquist
Publication date: 01-07-2018
Publisher: Springer Berlin Heidelberg
Published in: Supportive Care in Cancer / Issue 7/2018
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-018-4084-6

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