Skip to main content
Top
Published in: Supportive Care in Cancer 6/2016

01-06-2016 | Original Article

Psychological flexibility correlates with patient-reported outcomes independent of clinical or sociodemographic characteristics

Authors: Nicholas J. Hulbert-Williams, Lesley Storey

Published in: Supportive Care in Cancer | Issue 6/2016

Login to get access

Abstract

Purpose

The evidence for the effectiveness of psychological interventions for cancer patients is currently unclear. Acceptance and Commitment Therapy (ACT), which increases individual’s levels of psychological flexibility, may be more effective than other frameworks of psychological intervention, but good quality research is needed to inform adoption and implementation. This study explored the correlation between psychological flexibility and patient-reported outcomes to assess the viability of this intervention for cancer survivors.

Methods

Recruitment was coordinated through a regional cancer centre. One hundred twenty-nine respondents completed a cross-sectional postal questionnaire. They were of mixed gender, diagnosis and cancer stage; a mean 61 years old; and a mean 207 days post-diagnosis. Self-report questionnaires assessed psychological flexibility, mood, anxiety, depression, stress, quality of life and benefit finding.

Results

Psychological flexibility was a strong and consistent correlate of outcome; effects were maintained even when potentially confounding clinical and sociodemographic characteristics were controlled.

Conclusions

Psychological flexibility can be modified through ACT-based interventions. Given the strong correlational evidence found in this study, it seems that such interventions might be useful for cancer survivors. High-quality and well-designed controlled trials are now needed to establish effectiveness.
Literature
2.
go back to reference Macmillan (2006) Worried sick: the emotional impact of cancer. Macmillan Cancer Support, London UK Macmillan (2006) Worried sick: the emotional impact of cancer. Macmillan Cancer Support, London UK
3.
go back to reference Maguire P (2000) Psychological aspects. In: Dixon M (ed) ABC of breast diseases. BMJ Books, London, pp 150–153 Maguire P (2000) Psychological aspects. In: Dixon M (ed) ABC of breast diseases. BMJ Books, London, pp 150–153
5.
go back to reference Edwards AGK, Hulbert-Williams NJ, Neal RD (2008). Psychological interventions for women with metastatic breast cancer. Cochrane Database of Systematic Reviews Issue 2. Art. No.: CD004253, doi: 10.1002/14651858.CD004253.pub3. Edwards AGK, Hulbert-Williams NJ, Neal RD (2008). Psychological interventions for women with metastatic breast cancer. Cochrane Database of Systematic Reviews Issue 2. Art. No.: CD004253, doi: 10.​1002/​14651858.​CD004253.​pub3.
7.
go back to reference Hayes SC, Strosahl KD, Wilson KG (2011) Acceptance and Commitment Therapy: the process and practice of mindful change. Guildford Press, New York Hayes SC, Strosahl KD, Wilson KG (2011) Acceptance and Commitment Therapy: the process and practice of mindful change. Guildford Press, New York
9.
go back to reference Hulbert-Williams NJ, Storey L, Wilson KG (2015) Psychological interventions for patients with cancer: psychological flexibility and the potential utility of Acceptance and Commitment Therapy. Eur J Cancer Care (Engl) 24:15–27. doi:10.1111/ecc.12223 CrossRef Hulbert-Williams NJ, Storey L, Wilson KG (2015) Psychological interventions for patients with cancer: psychological flexibility and the potential utility of Acceptance and Commitment Therapy. Eur J Cancer Care (Engl) 24:15–27. doi:10.​1111/​ecc.​12223 CrossRef
11.
go back to reference Powers MB, Zum Vörde Sive Vörding MB, Emmelkamp PMG (2009) Acceptance and Commitment Therapy: a meta-analytic review. Psychother Psychosomatics 78:73–80. doi:10.1159/000190790 CrossRef Powers MB, Zum Vörde Sive Vörding MB, Emmelkamp PMG (2009) Acceptance and Commitment Therapy: a meta-analytic review. Psychother Psychosomatics 78:73–80. doi:10.​1159/​000190790 CrossRef
14.
16.
go back to reference Wetherell JL, Afari N, Rutledge T, Sorrell JT, Stoddard JA, Petkus AJ, Solomon BC, Lehman DH, Liu L, Lang AJ, Atkinson JH (2011) A randomized, controlled trial of acceptance and commitment therapy and cognitive-behavioural therapy for chronic pain. Pain 152:2098–2107. doi:10.1016/j.pain.2011.05.016 CrossRefPubMed Wetherell JL, Afari N, Rutledge T, Sorrell JT, Stoddard JA, Petkus AJ, Solomon BC, Lehman DH, Liu L, Lang AJ, Atkinson JH (2011) A randomized, controlled trial of acceptance and commitment therapy and cognitive-behavioural therapy for chronic pain. Pain 152:2098–2107. doi:10.​1016/​j.​pain.​2011.​05.​016 CrossRefPubMed
17.
go back to reference Feros DL, Lane L, Ciarrochi J, Blackledge JT (2013) Acceptance and Commitment Therapy (ACT) for improving the lives of cancer patients: a preliminary study. Psycho-Oncology 22:459–464. doi:10.1002/pon.2083 PubMed Feros DL, Lane L, Ciarrochi J, Blackledge JT (2013) Acceptance and Commitment Therapy (ACT) for improving the lives of cancer patients: a preliminary study. Psycho-Oncology 22:459–464. doi:10.​1002/​pon.​2083 PubMed
18.
go back to reference Rost AD, Wilson KG, Buchanan E, Hildebrandt MJ, Mutch D (2012) Improving psychological adjustment among late-stage ovarian cancer patients: examining the role of avoidance in treatment. Cogn Behav Pract 19:508–517. doi:10.1016/j.cbpra.2012.01.003 CrossRef Rost AD, Wilson KG, Buchanan E, Hildebrandt MJ, Mutch D (2012) Improving psychological adjustment among late-stage ovarian cancer patients: examining the role of avoidance in treatment. Cogn Behav Pract 19:508–517. doi:10.​1016/​j.​cbpra.​2012.​01.​003 CrossRef
19.
go back to reference Gillanders DT, Sinclair AK, MacLean M & Jardine K (2015). Illness cognitions, cognitive fusion, avoidance and self-compassion as predictors of distress and quality of life in a heterogenous sample of adults, after cancer. J Contextual Behav Scie, 1–2. DOI: 10.1016/j.jcbs.2015.07.003 Gillanders DT, Sinclair AK, MacLean M & Jardine K (2015). Illness cognitions, cognitive fusion, avoidance and self-compassion as predictors of distress and quality of life in a heterogenous sample of adults, after cancer. J Contextual Behav Scie, 1–2. DOI: 10.1016/j.jcbs.2015.07.003
20.
go back to reference Luoma JB, Kohlenberg BS, Hayes SC, Fletcher L (2012) Slow and steady wins the race: a randomized clinical trial of acceptance and commitment therapy targeting shame in substance use disorders. J Consult Clin Psychol 80:43–53. doi:10.1037/a0026070 CrossRefPubMed Luoma JB, Kohlenberg BS, Hayes SC, Fletcher L (2012) Slow and steady wins the race: a randomized clinical trial of acceptance and commitment therapy targeting shame in substance use disorders. J Consult Clin Psychol 80:43–53. doi:10.​1037/​a0026070 CrossRefPubMed
21.
go back to reference Trompetter HR, Bholmeijer ET, Veehof MM, Schreurs KMG (2014). Internet-based guided self-help intervention for chronic pain based on Acceptance and Commitment Therapy: a randomized controlled trial. Journal of Behavioral Medicine, e-publication ahead of print doi: 10.1007/s10865-014-9579-0. Trompetter HR, Bholmeijer ET, Veehof MM, Schreurs KMG (2014). Internet-based guided self-help intervention for chronic pain based on Acceptance and Commitment Therapy: a randomized controlled trial. Journal of Behavioral Medicine, e-publication ahead of print doi: 10.1007/s10865-014-9579-0.
24.
go back to reference Bond FW, Hayes SC, Baer RA, Carpenter KM, Guenole N, Orcutt HK, Waltz T, Zettle RD (2011) Preliminary psychometric properties of the Acceptance and Action Questionnaire-II: a revised measure of psychological inflexibility and experiential avoidance. Behav Ther 42:676–688. doi:10.1016/j.beth.2011.03.007 CrossRefPubMed Bond FW, Hayes SC, Baer RA, Carpenter KM, Guenole N, Orcutt HK, Waltz T, Zettle RD (2011) Preliminary psychometric properties of the Acceptance and Action Questionnaire-II: a revised measure of psychological inflexibility and experiential avoidance. Behav Ther 42:676–688. doi:10.​1016/​j.​beth.​2011.​03.​007 CrossRefPubMed
27.
go back to reference Meyer B (2001) Coping with severe mental illness: relations of the brief COPE with symptoms, functioning, and well-being. J Psychopathol Behav Assess 23:265–277CrossRef Meyer B (2001) Coping with severe mental illness: relations of the brief COPE with symptoms, functioning, and well-being. J Psychopathol Behav Assess 23:265–277CrossRef
28.
go back to reference Watson M, Law MG, dos Santos M, Greer S, Baruch J, Bliss J (1994) The Mini-MAC: Further development of the Mental Adjustment to Cancer Scale. J Psychosoc Oncol 12:33–46. doi:10.1300/J077V12N03_03 CrossRef Watson M, Law MG, dos Santos M, Greer S, Baruch J, Bliss J (1994) The Mini-MAC: Further development of the Mental Adjustment to Cancer Scale. J Psychosoc Oncol 12:33–46. doi:10.​1300/​J077V12N03_​03 CrossRef
31.
go back to reference Cohen S, Kamarack T, Mermelstein R (1983) A global measure of perceived stress. J Health Soc Behav 3:385–396CrossRef Cohen S, Kamarack T, Mermelstein R (1983) A global measure of perceived stress. J Health Soc Behav 3:385–396CrossRef
32.
go back to reference Cella DF, Tulsky DS, Gray G, Sarafian B, Linn E, Bonomi A, Silberman M, Yellen SB, Winicour P, Brannon J (1993) The Functional Assessment of Cancer Therapy (FACT) scale: development and validation of the general measure. J Clin Oncol 11:570–579PubMed Cella DF, Tulsky DS, Gray G, Sarafian B, Linn E, Bonomi A, Silberman M, Yellen SB, Winicour P, Brannon J (1993) The Functional Assessment of Cancer Therapy (FACT) scale: development and validation of the general measure. J Clin Oncol 11:570–579PubMed
34.
go back to reference Tabachnick BG, Fidell LS (2006) Using multivariate statistics, 5th edn. Pearson Education Ltd., London UK Tabachnick BG, Fidell LS (2006) Using multivariate statistics, 5th edn. Pearson Education Ltd., London UK
35.
go back to reference Stanton AL, Leucken LJ, MacKinnon DP, Thompson EH (2013) Mechanisms in psychosocial interventions for adults living with cancer: opportunity for integration of theory, research, and practice. J Consult Clin Psychol 81:318–335. doi:10.1037/a0028833 CrossRefPubMed Stanton AL, Leucken LJ, MacKinnon DP, Thompson EH (2013) Mechanisms in psychosocial interventions for adults living with cancer: opportunity for integration of theory, research, and practice. J Consult Clin Psychol 81:318–335. doi:10.​1037/​a0028833 CrossRefPubMed
37.
go back to reference Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M (2008) Developing and evaluating complex interventions: the new Medical Research Council Guidance. Br Med J 337:1655. doi:10.1136/bmj.a1655 CrossRef Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M (2008) Developing and evaluating complex interventions: the new Medical Research Council Guidance. Br Med J 337:1655. doi:10.​1136/​bmj.​a1655 CrossRef
38.
go back to reference Ciarrochi J, Fisher D, Lane L (2011) The link between value motives, value success, and well-being among people diagnosed with cancer. Psycho-Oncology 20:1184–1192CrossRefPubMed Ciarrochi J, Fisher D, Lane L (2011) The link between value motives, value success, and well-being among people diagnosed with cancer. Psycho-Oncology 20:1184–1192CrossRefPubMed
Metadata
Title
Psychological flexibility correlates with patient-reported outcomes independent of clinical or sociodemographic characteristics
Authors
Nicholas J. Hulbert-Williams
Lesley Storey
Publication date
01-06-2016
Publisher
Springer Berlin Heidelberg
Published in
Supportive Care in Cancer / Issue 6/2016
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-015-3050-9

Other articles of this Issue 6/2016

Supportive Care in Cancer 6/2016 Go to the issue
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine