Skip to main content
Top
Published in: Supportive Care in Cancer 6/2016

01-06-2016 | Original Article

Psychometric properties of the Arabic version of EORTC QLQ-C15-PAL among cancer patients in Jordan

Authors: Alia Alawneh, Hesham Yasin, Ghaleb Khirfan, Bashar Abu Qayas, Khawla Ammar, Dalia Rimawi, Pål Klepstad

Published in: Supportive Care in Cancer | Issue 6/2016

Login to get access

Abstract

Purpose

Health related quality of life (HRQOL) is an important outcome in cancer care and needs assessment by a valid questionnaire. HRQOL questionnaires need to be validated after translations to other languages and cultural settings. The purpose of this study is to evaluate the psychometric properties of the Arabic version of the European Organization for Research and Treatment of Cancer Quality of Life 15 items Questionnaire for Palliative Care (EORTC QLQ-C15-PAL).

Methods

This is a cross-sectional study of a convenient sample of inpatients with cancer.

Results

One hundred seventy-five patients completed the EORTC QLQ-C15-PAL questionnaire. Cronbach’s alpha coefficient met the 0.7 alpha criterion. Confirmatory factor analysis met the goodness of fit criteria; goodness-of-fit index (GFI), comparative fit index (CFI), normed fit index (NFI) and non-normed fit index (NNFI) >0.90 and root mean square error of approximation (RMSEA) <0.06. All item-scale correlation coefficients exceeded the set value of 0.40, indicating satisfactory convergent validity. In terms of discriminant validity, all items in the questionnaire showed a higher item-scale correlation than item-other scale correlation, except for items 1 and 2 (physical function scale) that showed a higher correlation with fatigue. Construct validity was tested by item inter scale correlation coefficient. All constructs had correlation coefficient <0.70. External validity was tested by comparison of scores of patients who had metastasis and who did not have metastasis. Significant differences (P value <0.05) were found in all scales except for nausea. Age groups were compared and showed significant differences for physical function, fatigue, and global score of HRQOL.

Conclusion

The Arabic version of the EORTC QLQ-C15-PAL is valid and reliable.
Appendix
Available only for authorised users
Literature
2.
go back to reference Arraras JI, Duenas T, Meirino R, Pruja E, Villafranca E, Valerdi JJ (1998) Quality of life of cancer patients: studies by the Oncology Department of the Hospital of Navarra in the Quality of Life Group of the EORTC. Anales del sistema sanitario de Navarra 21(1):47–53PubMed Arraras JI, Duenas T, Meirino R, Pruja E, Villafranca E, Valerdi JJ (1998) Quality of life of cancer patients: studies by the Oncology Department of the Hospital of Navarra in the Quality of Life Group of the EORTC. Anales del sistema sanitario de Navarra 21(1):47–53PubMed
3.
go back to reference Bottomley A, Vanvoorden V, Flechtner H, Therasse P (2003) The challenges and achievements involved in implementing Quality of Life research in cancer clinical trials. Eur J Cancer 39(3):275–285CrossRefPubMed Bottomley A, Vanvoorden V, Flechtner H, Therasse P (2003) The challenges and achievements involved in implementing Quality of Life research in cancer clinical trials. Eur J Cancer 39(3):275–285CrossRefPubMed
4.
go back to reference Groenvold M, Petersen MA, Aaronson NK, Arraras JI, Blazeby JM, Bottomley A, Fayers PM, de Graeff A, Hammerlid E, Kaasa S, Sprangers MA, Bjorner JB (2006) The development of the EORTC QLQ-C15-PAL: a shortened questionnaire for cancer patients in palliative care. Eur J Cancer 42(1):55–64. doi:10.1016/j.ejca.2005.06.022 CrossRefPubMed Groenvold M, Petersen MA, Aaronson NK, Arraras JI, Blazeby JM, Bottomley A, Fayers PM, de Graeff A, Hammerlid E, Kaasa S, Sprangers MA, Bjorner JB (2006) The development of the EORTC QLQ-C15-PAL: a shortened questionnaire for cancer patients in palliative care. Eur J Cancer 42(1):55–64. doi:10.​1016/​j.​ejca.​2005.​06.​022 CrossRefPubMed
6.
go back to reference Arraras JI, de la Vega FA, Asin G, Rico M, Zarandona U, Eito C, Cambra K, Barrondo M, Errasti M, Verdun J, Rivadeneira J, Dominguez MA (2014) The EORTC QLQ-C15-PAL questionnaire: validation study for Spanish bone metastases patients. Qual Life Res 23(3):849–855. doi:10.1007/s11136-013-0511-9 CrossRefPubMed Arraras JI, de la Vega FA, Asin G, Rico M, Zarandona U, Eito C, Cambra K, Barrondo M, Errasti M, Verdun J, Rivadeneira J, Dominguez MA (2014) The EORTC QLQ-C15-PAL questionnaire: validation study for Spanish bone metastases patients. Qual Life Res 23(3):849–855. doi:10.​1007/​s11136-013-0511-9 CrossRefPubMed
7.
go back to reference Miyashita M, Wada M, Morita T, Ishida M, Onishi H, Sasaki Y, Narabayashi M, Wada T, Matsubara M, Takigawa C, Shinjo T, Suga A, Inoue S, Ikenaga M, Kohara H, Tsuneto S, Shima Y (2015) Independent validation of the Japanese version of the EORTC QLQ-C15-PAL for patients with advanced cancer. J Pain Symptom Manag. doi:10.1016/j.jpainsymman.2014.11.299 Miyashita M, Wada M, Morita T, Ishida M, Onishi H, Sasaki Y, Narabayashi M, Wada T, Matsubara M, Takigawa C, Shinjo T, Suga A, Inoue S, Ikenaga M, Kohara H, Tsuneto S, Shima Y (2015) Independent validation of the Japanese version of the EORTC QLQ-C15-PAL for patients with advanced cancer. J Pain Symptom Manag. doi:10.​1016/​j.​jpainsymman.​2014.​11.​299
8.
go back to reference Miyazaki K, Suzukamo Y, Shimozuma K, Nakayama T (2012) Verification of the psychometric properties of the Japanese version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 palliative (EORTCQLQ-C15-PAL). Qual Life Res 21(2):335–340. doi:10.1007/s11136-011-9939-y CrossRefPubMed Miyazaki K, Suzukamo Y, Shimozuma K, Nakayama T (2012) Verification of the psychometric properties of the Japanese version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 palliative (EORTCQLQ-C15-PAL). Qual Life Res 21(2):335–340. doi:10.​1007/​s11136-011-9939-y CrossRefPubMed
9.
go back to reference Nunes NAH (2014) The quality of life of Brazilian patients in palliative care: validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 PAL (EORTC QLQ-C15-PAL). Support Care Cancer 22(6):1595–1600. doi:10.1007/s00520-014-2119-1 CrossRefPubMed Nunes NAH (2014) The quality of life of Brazilian patients in palliative care: validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 PAL (EORTC QLQ-C15-PAL). Support Care Cancer 22(6):1595–1600. doi:10.​1007/​s00520-014-2119-1 CrossRefPubMed
10.
go back to reference Shin DW, Choi JE, Miyashita M, Choi JY, Kang J, Baik YJ, Mo HN, Park J, Kim HJ, Park EC (2011) Cross-cultural application of the Korean version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 15-Palliative Care. J Pain Symptom Manag 41(2):478–484. doi:10.1016/j.jpainsymman.2010.05.009 CrossRef Shin DW, Choi JE, Miyashita M, Choi JY, Kang J, Baik YJ, Mo HN, Park J, Kim HJ, Park EC (2011) Cross-cultural application of the Korean version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 15-Palliative Care. J Pain Symptom Manag 41(2):478–484. doi:10.​1016/​j.​jpainsymman.​2010.​05.​009 CrossRef
11.
go back to reference Suarez-del-Real Y, Allende-Perez S, Alferez-Mancera A, Rodriguez RB, Jimenez-Toxtle S, Mohar A, Onate-Ocana LF (2011) Validation of the Mexican-Spanish version of the EORTC QLQ-C15-PAL questionnaire for the evaluation of health-related quality of life in patients on palliative care. Psycho-Oncology 20(8):889–896. doi:10.1002/pon.1801 CrossRefPubMed Suarez-del-Real Y, Allende-Perez S, Alferez-Mancera A, Rodriguez RB, Jimenez-Toxtle S, Mohar A, Onate-Ocana LF (2011) Validation of the Mexican-Spanish version of the EORTC QLQ-C15-PAL questionnaire for the evaluation of health-related quality of life in patients on palliative care. Psycho-Oncology 20(8):889–896. doi:10.​1002/​pon.​1801 CrossRefPubMed
12.
go back to reference Fatiha Sadat FK, Atefeh Farzindar Automatic Identification of Arabic Language Varieties and Dialects in Social Media. Proceedings of the Second Workshop on Natural Language Processing for Social Media (SocialNLP), pages 22–27, Dublin, Ireland, August 24 2014 Fatiha Sadat FK, Atefeh Farzindar Automatic Identification of Arabic Language Varieties and Dialects in Social Media. Proceedings of the Second Workshop on Natural Language Processing for Social Media (SocialNLP), pages 22–27, Dublin, Ireland, August 24 2014
14.
go back to reference Linda Dewolf MK, Galina Velikova, Colin Johnson, Neil Scott, Andrew Bottomley on behalf of the EORTC Quality of Life Group (2009) Linda Dewolf MK, Galina Velikova, Colin Johnson, Neil Scott, Andrew Bottomley on behalf of the EORTC Quality of Life Group (2009)
15.
16.
go back to reference Hjermstad MJ, Fayers PM, Bjordal K, Kaasa S (1998) Health-related quality of life in the general Norwegian population assessed by the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire: the QLQ = C30 (+3). J Clin Oncol 16(3):1188–1196PubMed Hjermstad MJ, Fayers PM, Bjordal K, Kaasa S (1998) Health-related quality of life in the general Norwegian population assessed by the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire: the QLQ = C30 (+3). J Clin Oncol 16(3):1188–1196PubMed
17.
go back to reference Lam K, Zeng L, Zhang L, Tseng LM, Hou MF, Fairchild A, Vassiliou V, Jesus-Garcia R, Alm El-Din MA, Kumar A, Forges F, Chie WC, Sahgal A, Poon M, Chow E (2013) Predictive factors of overall well-being using the EORTC QLQ-C15-PAL extracted from the EORTC QLQ-C30. J Palliat Med 16(4):402–408. doi:10.1089/jpm.2012.0398 CrossRefPubMed Lam K, Zeng L, Zhang L, Tseng LM, Hou MF, Fairchild A, Vassiliou V, Jesus-Garcia R, Alm El-Din MA, Kumar A, Forges F, Chie WC, Sahgal A, Poon M, Chow E (2013) Predictive factors of overall well-being using the EORTC QLQ-C15-PAL extracted from the EORTC QLQ-C30. J Palliat Med 16(4):402–408. doi:10.​1089/​jpm.​2012.​0398 CrossRefPubMed
Metadata
Title
Psychometric properties of the Arabic version of EORTC QLQ-C15-PAL among cancer patients in Jordan
Authors
Alia Alawneh
Hesham Yasin
Ghaleb Khirfan
Bashar Abu Qayas
Khawla Ammar
Dalia Rimawi
Pål Klepstad
Publication date
01-06-2016
Publisher
Springer Berlin Heidelberg
Published in
Supportive Care in Cancer / Issue 6/2016
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-015-3018-9

Other articles of this Issue 6/2016

Supportive Care in Cancer 6/2016 Go to the issue
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine