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Supportive Care in Cancer
Published in: Supportive Care in Cancer 12/2013

01-12-2013 | Original Article

Treatment regret and quality of life following radical prostatectomy

Authors: Chelsea G. Ratcliff, Lorenzo Cohen, Curtis A. Pettaway, Patricia A. Parker

Published in: Supportive Care in Cancer | Issue 12/2013

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Abstract

Purpose

Negative physical functioning outcomes including incontinence and erectile dysfunction are relatively common following radical prostatectomy (RP) and are associated with treatment regret and compromised quality of life (QOL). The role that treatment regret may have in influencing the association between prostate-specific QOL (i.e., sexual, urinary, bowl functioning) and general QOL following RP has not been examined.

Method

This study examined the associations of treatment regret, general QOL (36-item Short Form Health Survey physical and mental health (MCS) composite scores), and prostate-specific QOL (Prostate Cancer QOL sexual, urinary, bowl functioning, and cancer worry subscales) in 95 men who underwent RP for prostate cancer.

Results

Multiple regression analyses indicated that poorer sexual and urinary functioning was associated with poorer MCS. Additionally, men with lower sexual and urinary functioning reported greater treatment regret. Treatment regret was also associated with lower MCS. Finally, treatment regret partially mediated the effects of both sexual and urinary functioning on MCS.

Conclusions

These findings suggest that regardless of a patient's prostate-specific QOL, reducing treatment regret may improve mental health following RP. Though there are limited options to alter patients' sexual or urinary functioning following RP, treatment regret may be a modifiable contributor to post-surgical adjustment and QOL.
Appendix
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Metadata
Title
Treatment regret and quality of life following radical prostatectomy
Authors
Chelsea G. Ratcliff
Lorenzo Cohen
Curtis A. Pettaway
Patricia A. Parker
Publication date
01-12-2013
Publisher
Springer Berlin Heidelberg
Published in
Supportive Care in Cancer / Issue 12/2013
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-013-1906-4

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