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Supportive Care in Cancer
Published in: Supportive Care in Cancer 9/2011

01-09-2011 | Original Article

Quality of life concerns and depression among hematopoietic stem cell transplant survivors

Authors: Catherine E. Mosher, Katherine N. DuHamel, Christine Rini, Geoffrey Corner, Joanne Lam, William H. Redd

Published in: Supportive Care in Cancer | Issue 9/2011

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Abstract

Purpose

This study examined quality of life, transplant-related concerns, and depressive symptoms and their demographic and medical correlates at 1 to 3 years following hematopoietic stem cell transplantation (HSCT).

Methods

HSCT survivors (N = 406) completed telephone-administered questionnaires that assessed demographic variables, functional status, quality of life, transplant-related concerns, and depressive symptoms.

Results

The most prevalent concerns among HSCT survivors included physical symptoms (e.g., fatigue and pain), maintaining current health status and employment, changes in appearance, and lack of sexual interest and satisfaction. In addition, almost one-third (32%) of survivors age 40 years and younger reported concern about their ability to have children. Unemployed survivors and those with lower incomes and worse functional status were more likely to experience poorer quality of life in multiple domains. Fifteen percent of the sample reported moderate to severe depressive symptoms, and these symptoms were higher among allogeneic transplant recipients and those with lower functional status.

Conclusions

Results suggest that interventions are needed to address physical symptoms, coping with an uncertain future, infertility, and sexual issues during the early phase of HSCT survivorship.
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Metadata
Title
Quality of life concerns and depression among hematopoietic stem cell transplant survivors
Authors
Catherine E. Mosher
Katherine N. DuHamel
Christine Rini
Geoffrey Corner
Joanne Lam
William H. Redd
Publication date
01-09-2011
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 9/2011
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-010-0958-y

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