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Supportive Care in Cancer
Published in: Supportive Care in Cancer 8/2008

01-08-2008 | Review Article

Impact of skeletal complications on patients’ quality of life, mobility, and functional independence

Authors: Luis Costa, Xavier Badia, Edward Chow, Allan Lipton, Andrew Wardley

Published in: Supportive Care in Cancer | Issue 8/2008

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Abstract

Introduction

Skeletal-related events (SREs) from malignant bone disease cause considerable morbidity and can dramatically reduce patients’ quality of life.

Discussion

Pathologic fractures often require surgical intervention and palliative radiotherapy. Thus, patients suffer impaired mobility, loss of functional independence, and diminished health-related quality of life (HRQOL). Bisphosphonates can delay the onset and reduce the incidence of SREs and have become the standard of care for the treatment of malignant bone disease; however, minimal information on the effects of bisphosphonate treatment on HRQOL is available. Targeted HRQOL assessments for patients with malignant bone disease are currently under development and are discussed herein.
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Metadata
Title
Impact of skeletal complications on patients’ quality of life, mobility, and functional independence
Authors
Luis Costa
Xavier Badia
Edward Chow
Allan Lipton
Andrew Wardley
Publication date
01-08-2008
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 8/2008
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-008-0418-0

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