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Supportive Care in Cancer

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01-09-2007 | Original Article

Young survivors of malignant bone tumours in the extremities: a comparative study of quality of life, fatigue and mental distress

Authors: Liv Hege Aksnes, Kirsten Sundby Hall, Nina Jebsen, Sophie D. Fosså, Alv A. Dahl

Published in: Supportive Care in Cancer | Issue 9/2007

Abstract

Purpose

The purpose of the study was to compare the quality of life (QoL), fatigue and mental distress in survivors of malignant extremity bone tumours (EBT survivors) with age and gender-matched survivors of Hodgkin’s disease (HD survivors) and testicular cancer (TC survivors) as well as normative samples from the general population.

Patients and methods

Five years or more after end of treatment, 75 EBT survivors were mailed a questionnaire containing Short Form-36 (SF-36), the Hospital Anxiety and Depression Scale, the Fatigue Questionnaire and questions about demography. Fifty-eight EBT survivors responded. TC survivors, HD survivors and normative samples (NORMs) had earlier on filled in the same questionnaire. For EBT survivors, gender and age-matched controls were randomly selected among TC survivors, HD survivors and NORMs.

Results

No significant differences in the fatigue or mental distress scores were observed between the survivor groups. The EBT survivors had significantly higher fatigue scores and lower depression scores than NORMs and significantly lower scores on all physical dimensions of QoL than TC survivors, HD survivors and NORMs. In multivariate analysis, a low level of education and lack of employment were significantly associated with caseness of mental distress. Older age at survey, female gender, being an EBT survivor and lack of employment were associated with caseness on the SF-36 Physical Component Summary Scale.

Conclusion

At long-term follow-up, EBT survivors did not show impaired mental health or fatigue at the group level, although their post-treatment status was characterised by reduced QoL dimensions on physical function compared to TC survivors, HD survivors and NORMs.

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Title: Young survivors of malignant bone tumours in the extremities: a comparative study of quality of life, fatigue and mental distress
Authors: Liv Hege Aksnes
Kirsten Sundby Hall
Nina Jebsen
Sophie D. Fosså
Alv A. Dahl
Publication date: 01-09-2007
Publisher: Springer-Verlag
Published in: Supportive Care in Cancer / Issue 9/2007
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-007-0227-x

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Purpose

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Conclusion

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