Skip to main content
Top
Published in: Supportive Care in Cancer 7/2006

01-07-2006 | Review Article

A meta-analysis of exercise interventions among people treated for cancer

Authors: Vicki S. Conn, Adam R. Hafdahl, Davina C. Porock, Roxanne McDaniel, Paul J. Nielsen

Published in: Supportive Care in Cancer | Issue 7/2006

Login to get access

Abstract

Goal

This review applied meta-analytic procedures to integrate primary research findings that tested exercise interventions among people treated for cancer.

Methods

Extensive literature searching strategies located published and unpublished intervention studies that tested exercise interventions with at least five participants (k=30). Primary study results were coded. Meta-analytic procedures were conducted.

Main results

The overall weighted mean effect size (ES) for two-group comparisons was 0.52 (higher mean for treatment than control) for physical function, 0.35 for symptoms other than fatigue, and 0.27 for body composition. More modest positive ESs were documented for mood (0.19), quality of life (0.14), fatigue (0.11), and exercise behavior (0.04). ESs were larger among single-group pre–post design studies. ESs among control group participants were typically negative and not (statistically) significantly different from 0.

Conclusions

Exercise interventions resulted in small positive effects on health and well-being outcomes among existing studies. Future research should examine intervention-specific characteristics that result in optimal results, such as dose.
Appendix
Available only for authorised users
Literature
1.
go back to reference Aziz NM (2002) Cancer survivorship research: challenge and opportunity. J Nutr 132(11 Suppl):3494S–3503SPubMed Aziz NM (2002) Cancer survivorship research: challenge and opportunity. J Nutr 132(11 Suppl):3494S–3503SPubMed
2.
go back to reference Berglund G, Bolund C, Gustafsson UL, Sjoden PO (1994) One-year follow-up of the ’Starting Again’ group rehabilitation programme for cancer patients. Eur J Cancer 30A(12):1744–1751CrossRefPubMed Berglund G, Bolund C, Gustafsson UL, Sjoden PO (1994) One-year follow-up of the ’Starting Again’ group rehabilitation programme for cancer patients. Eur J Cancer 30A(12):1744–1751CrossRefPubMed
3.
go back to reference *Burnham TR, Wilcox A (2002) Effects of exercise on physiological and psychological variables in cancer survivors. Med Sci Sports Exerc 34(12):1863–1867CrossRefPubMed *Burnham TR, Wilcox A (2002) Effects of exercise on physiological and psychological variables in cancer survivors. Med Sci Sports Exerc 34(12):1863–1867CrossRefPubMed
4.
go back to reference Chlebowski RT, Aiello E, McTiernan A (2002) Weight loss in breast cancer patient management. J Clin Oncol 20(4):1128–1143PubMedCrossRef Chlebowski RT, Aiello E, McTiernan A (2002) Weight loss in breast cancer patient management. J Clin Oncol 20(4):1128–1143PubMedCrossRef
5.
go back to reference Conn V, Rantz M (2003) Research methods: managing primary study quality in meta-analyses. Res Nurs Health 26:322–333CrossRefPubMed Conn V, Rantz M (2003) Research methods: managing primary study quality in meta-analyses. Res Nurs Health 26:322–333CrossRefPubMed
6.
go back to reference Conn V, Rantz M, Maas M, Wipke-Tevis D (2001) Designing effective nursing interventions. Res Nurs Health 24(5):433–442CrossRefPubMed Conn V, Rantz M, Maas M, Wipke-Tevis D (2001) Designing effective nursing interventions. Res Nurs Health 24(5):433–442CrossRefPubMed
7.
go back to reference Conn V, Isamaralai S, Rath S, Jantarakupt P, Wadhawan R, Dash Y (2003) Beyond MEDLINE for literature searches. J Nurs Scholarsh 35:177–182CrossRefPubMed Conn V, Isamaralai S, Rath S, Jantarakupt P, Wadhawan R, Dash Y (2003) Beyond MEDLINE for literature searches. J Nurs Scholarsh 35:177–182CrossRefPubMed
8.
go back to reference Conn V, Valentine J, Cooper H, Rantz M (2003) Grey literature in meta-analyses. Nurs Res 52:256–261CrossRefPubMed Conn V, Valentine J, Cooper H, Rantz M (2003) Grey literature in meta-analyses. Nurs Res 52:256–261CrossRefPubMed
9.
go back to reference Cook DJ, Guyatt GH, Ryan G (1993) Should unpublished data be included in meta-analyses? JAMA 269:749–753CrossRef Cook DJ, Guyatt GH, Ryan G (1993) Should unpublished data be included in meta-analyses? JAMA 269:749–753CrossRef
10.
go back to reference Courneya KS, Friedenreich CM (1999) Physical exercise and quality of life following cancer diagnosis: a literature review. Ann Behav Med 21(2):171–179PubMedCrossRef Courneya KS, Friedenreich CM (1999) Physical exercise and quality of life following cancer diagnosis: a literature review. Ann Behav Med 21(2):171–179PubMedCrossRef
11.
go back to reference Courneya KS, Friedenreich CM (2001) Framework PEACE: an organizational model for examining physical exercise across the cancer experience. Ann Behav Med 23(4):263–272CrossRefPubMed Courneya KS, Friedenreich CM (2001) Framework PEACE: an organizational model for examining physical exercise across the cancer experience. Ann Behav Med 23(4):263–272CrossRefPubMed
12.
go back to reference *Courneya KS, Friedenreich C, Quinney HA, Fields ALA, Jones LW, Fairey AS (2003) A randomized trial of exercise and quality of life in colorectal cancer survivors. Eur J Cancer Care 12(4):347–357CrossRef *Courneya KS, Friedenreich C, Quinney HA, Fields ALA, Jones LW, Fairey AS (2003) A randomized trial of exercise and quality of life in colorectal cancer survivors. Eur J Cancer Care 12(4):347–357CrossRef
13.
go back to reference *Courneya KS, Friedenreich CM, Sela RA, Quinney HA, Rhodes RE, Handman M (2003) The group psychotherapy and home-based physical exercise (group–hope) trial in cancer survivors: physical fitness and quality of life outcomes. Psychooncology 12(4):357–374CrossRefPubMed *Courneya KS, Friedenreich CM, Sela RA, Quinney HA, Rhodes RE, Handman M (2003) The group psychotherapy and home-based physical exercise (group–hope) trial in cancer survivors: physical fitness and quality of life outcomes. Psychooncology 12(4):357–374CrossRefPubMed
14.
go back to reference *Courneya KS, Mackey JR, Bell GJ, Jones LW, Field CJ, Fairey AS (2003) Randomized controlled trial of exercise training in postmenopausal breast cancer survivors: cardiopulmonary and quality of life outcomes. J Clin Oncol 21(9):1660–1668PubMedCrossRef *Courneya KS, Mackey JR, Bell GJ, Jones LW, Field CJ, Fairey AS (2003) Randomized controlled trial of exercise training in postmenopausal breast cancer survivors: cardiopulmonary and quality of life outcomes. J Clin Oncol 21(9):1660–1668PubMedCrossRef
15.
go back to reference *Craddock RB, Adams PF, Usui WM, Mitchell L (1999) An intervention to increase use and effectiveness of self-care measures for breast cancer chemotherapy patients. Cancer Nurs 22(4):312–319CrossRefPubMed *Craddock RB, Adams PF, Usui WM, Mitchell L (1999) An intervention to increase use and effectiveness of self-care measures for breast cancer chemotherapy patients. Cancer Nurs 22(4):312–319CrossRefPubMed
16.
go back to reference Cunningham BA, Morris G, Cheney CL, Buergel N, Aker SN, Lenssen P (1986) Effects of resistive exercise on skeletal muscle in marrow transplant recipients receiving total parenteral nutrition. JPEN J Parenter Enteral Nutr 10(6):558–563PubMedCrossRef Cunningham BA, Morris G, Cheney CL, Buergel N, Aker SN, Lenssen P (1986) Effects of resistive exercise on skeletal muscle in marrow transplant recipients receiving total parenteral nutrition. JPEN J Parenter Enteral Nutr 10(6):558–563PubMedCrossRef
17.
go back to reference Decker WA, Turner-McGlade J, Fehir KM (1989) Psychosocial aspects and the physiological effects of a cardiopulmonary exercise program in patients undergoing bone marrow transplantation (BMT) for acute leukemia (AL). Transplant Proc 21(1 Pt3):3068–3069PubMed Decker WA, Turner-McGlade J, Fehir KM (1989) Psychosocial aspects and the physiological effects of a cardiopulmonary exercise program in patients undergoing bone marrow transplantation (BMT) for acute leukemia (AL). Transplant Proc 21(1 Pt3):3068–3069PubMed
18.
go back to reference Devine E (2003) Meta-analysis of the effect of psychoeducational interventions on pain in adults with cancer. Oncol Nurs Forum 30:75–89PubMedCrossRef Devine E (2003) Meta-analysis of the effect of psychoeducational interventions on pain in adults with cancer. Oncol Nurs Forum 30:75–89PubMedCrossRef
19.
go back to reference *Dimeo F, Bertz H, Finke J, Fetscher S, Mertelsmann R, Keul J (1996) An aerobic exercise program for patients with haematological malignancies after bone marrow transplantation. Bone Marrow Transplant 18(6):1157–1160PubMed *Dimeo F, Bertz H, Finke J, Fetscher S, Mertelsmann R, Keul J (1996) An aerobic exercise program for patients with haematological malignancies after bone marrow transplantation. Bone Marrow Transplant 18(6):1157–1160PubMed
20.
go back to reference *Dimeo F, Tilmann MH, Bertz H, Kanz L, Mertelsmann R, Keul J (1997) Aerobic exercise in the rehabilitation of cancer patients after high dose chemotherapy and autologous peripheral stem cell transplantation. Cancer 79(9):1717–1722CrossRefPubMed *Dimeo F, Tilmann MH, Bertz H, Kanz L, Mertelsmann R, Keul J (1997) Aerobic exercise in the rehabilitation of cancer patients after high dose chemotherapy and autologous peripheral stem cell transplantation. Cancer 79(9):1717–1722CrossRefPubMed
21.
go back to reference *Dimeo F, Fetscher S, Lange W, Mertelsmann R, Keul J (1997) Effects of aerobic exercise on the physical performance and incidence of treatment-related complications after high-dose chemotherapy. Blood 90(9):3390–3390PubMed *Dimeo F, Fetscher S, Lange W, Mertelsmann R, Keul J (1997) Effects of aerobic exercise on the physical performance and incidence of treatment-related complications after high-dose chemotherapy. Blood 90(9):3390–3390PubMed
22.
go back to reference *Dimeo F, Rumberger BG, Keul J (1998) Aerobic exercise as therapy for cancer fatigue. Med Sci Sports Exerc 30(4):475–478PubMed *Dimeo F, Rumberger BG, Keul J (1998) Aerobic exercise as therapy for cancer fatigue. Med Sci Sports Exerc 30(4):475–478PubMed
23.
go back to reference *Dimeo FC, Stieglitz RD, Novelli-Fischer U, Fetscher S, Keul J (1999) Effects of physical activity on the fatigue and psychologic status of cancer patients during chemotherapy. Cancer 85(10):2273–2277CrossRefPubMed *Dimeo FC, Stieglitz RD, Novelli-Fischer U, Fetscher S, Keul J (1999) Effects of physical activity on the fatigue and psychologic status of cancer patients during chemotherapy. Cancer 85(10):2273–2277CrossRefPubMed
24.
go back to reference *Durak EP, Lilly PC (1998) The application of an exercise and wellness program for cancer patients: a preliminary outcomes report. J Strength Cond Res 12(1):3–6CrossRef *Durak EP, Lilly PC (1998) The application of an exercise and wellness program for cancer patients: a preliminary outcomes report. J Strength Cond Res 12(1):3–6CrossRef
25.
go back to reference *Durak E, Lilly PC (1999) Preliminary results of exercise in breast cancer: a two-year follow-up survey. J Rehabil Outcomes Meas 3(4):53–60 *Durak E, Lilly PC (1999) Preliminary results of exercise in breast cancer: a two-year follow-up survey. J Rehabil Outcomes Meas 3(4):53–60
26.
go back to reference *Durak EP, Lilly PC, Hackworth JL (1999) Physical and psychosocial responses to exercise in cancer patients: a two year follow-up survey with prostrate, leukemia, and general carcinoma. J Exerc Physiol Online 2(1) *Durak EP, Lilly PC, Hackworth JL (1999) Physical and psychosocial responses to exercise in cancer patients: a two year follow-up survey with prostrate, leukemia, and general carcinoma. J Exerc Physiol Online 2(1)
27.
go back to reference Fairey AS, Courneya KS, Field CJ, Mackey JR (2002) Physical exercise and immune system function in cancer survivors: a comprehensive review and future directions. Cancer 94(2):539–551CrossRefPubMed Fairey AS, Courneya KS, Field CJ, Mackey JR (2002) Physical exercise and immune system function in cancer survivors: a comprehensive review and future directions. Cancer 94(2):539–551CrossRefPubMed
28.
go back to reference Friedenreich CM, Courneya KS (1996) Exercise as rehabilitation for cancer patients. Clin J Sport Med 6(4):237–244PubMedCrossRef Friedenreich CM, Courneya KS (1996) Exercise as rehabilitation for cancer patients. Clin J Sport Med 6(4):237–244PubMedCrossRef
29.
go back to reference Galvao D, Newton R (2005) Review of exercise intervention studies in cancer patients. J Clin Oncol 23(4):899–909CrossRefPubMed Galvao D, Newton R (2005) Review of exercise intervention studies in cancer patients. J Clin Oncol 23(4):899–909CrossRefPubMed
30.
go back to reference Gleser LJ, Olkin I (1994) Stochastically dependent effect sizes. In: Cooper H, Hedges L (eds) The handbook of research synthesis. Russell Sage Foundation, New York, pp 339–355 Gleser LJ, Olkin I (1994) Stochastically dependent effect sizes. In: Cooper H, Hedges L (eds) The handbook of research synthesis. Russell Sage Foundation, New York, pp 339–355
31.
go back to reference *Goodwin P, Esplen MJ, Butler K, Winocur J, Pritchard K, Brazel S, Gao A, Miller J (1998) Multidisciplinary weight management in locoregional breast cancer: results of a phase II study. Breast Cancer Res Treat 48(1):53–64CrossRefPubMed *Goodwin P, Esplen MJ, Butler K, Winocur J, Pritchard K, Brazel S, Gao A, Miller J (1998) Multidisciplinary weight management in locoregional breast cancer: results of a phase II study. Breast Cancer Res Treat 48(1):53–64CrossRefPubMed
32.
go back to reference *Hayes S, Davies PS, Parker T, Bashford J (2003) Total energy expenditure and body composition changes following peripheral blood stem cell transplantation and participation in an exercise programme. Bone Marrow Transplant 31(5):331–338CrossRefPubMed *Hayes S, Davies PS, Parker T, Bashford J (2003) Total energy expenditure and body composition changes following peripheral blood stem cell transplantation and participation in an exercise programme. Bone Marrow Transplant 31(5):331–338CrossRefPubMed
33.
go back to reference Hedges L (1994) Fixed effects models. In: Cooper H, Hedges L (eds) The handbook of research synthesis. Russell Sage Foundation, New York, pp 285–299 Hedges L (1994) Fixed effects models. In: Cooper H, Hedges L (eds) The handbook of research synthesis. Russell Sage Foundation, New York, pp 285–299
34.
go back to reference Hedges L, Olkin I (1985) Statistical methods for meta-analysis. Academic, Orlando Hedges L, Olkin I (1985) Statistical methods for meta-analysis. Academic, Orlando
35.
go back to reference Hedges L, Vevea J (1998) Fixed- and random-effects models in meta-analysis. Psychol Methods 3:486–504CrossRef Hedges L, Vevea J (1998) Fixed- and random-effects models in meta-analysis. Psychol Methods 3:486–504CrossRef
36.
go back to reference *Holley S, Borger D (2001) Energy for living with cancer: preliminary findings of a cancer rehabilitation group intervention study. Oncol Nurs Forum 28(9):1393–1396PubMed *Holley S, Borger D (2001) Energy for living with cancer: preliminary findings of a cancer rehabilitation group intervention study. Oncol Nurs Forum 28(9):1393–1396PubMed
37.
go back to reference Holtzman J, Schmitz K, Babes G, Kane R, Duval S, Wilt T, MacDonald R, Rutks I (2004) Effectiveness of behavioral interventions to modify physical activity behaviors in general populations and cancer patients and survivors (evidence report/technology assessment no. 102 no. AHRQ publication no. 04-E027-02). Agency for Healthcare Research and Quality, Rockville Holtzman J, Schmitz K, Babes G, Kane R, Duval S, Wilt T, MacDonald R, Rutks I (2004) Effectiveness of behavioral interventions to modify physical activity behaviors in general populations and cancer patients and survivors (evidence report/technology assessment no. 102 no. AHRQ publication no. 04-E027-02). Agency for Healthcare Research and Quality, Rockville
38.
go back to reference Irwin ML, Ainsworth BE (2004) Physical activity interventions following cancer diagnosis: methodologic challenges to delivery and assessment. Cancer Invest 22:30–50CrossRefPubMed Irwin ML, Ainsworth BE (2004) Physical activity interventions following cancer diagnosis: methodologic challenges to delivery and assessment. Cancer Invest 22:30–50CrossRefPubMed
39.
go back to reference Kalaian HA, Raudenbush SW (1996) A multivariate mixed linear model for meta-analysis. Psychol Methods 1:227–235CrossRef Kalaian HA, Raudenbush SW (1996) A multivariate mixed linear model for meta-analysis. Psychol Methods 1:227–235CrossRef
40.
go back to reference Kolden GG, Strauman TJ, Ward A, Kuta J, Woods TE, Schneider KL, Heerey E, Sanborn L, Burt C, Millbrandt L, Kalin NH, Stewart JA, Mullen B (2002) A pilot study of group exercise training (GET) for women with primary breast cancer: feasibility and health benefits. Psychooncology 11(5):447–456PubMedCrossRef Kolden GG, Strauman TJ, Ward A, Kuta J, Woods TE, Schneider KL, Heerey E, Sanborn L, Burt C, Millbrandt L, Kalin NH, Stewart JA, Mullen B (2002) A pilot study of group exercise training (GET) for women with primary breast cancer: feasibility and health benefits. Psychooncology 11(5):447–456PubMedCrossRef
41.
go back to reference Kuhn K, Boesen E, Ross L, Johansen C (2005) Evaluation and outcome of behavioural changes in the rehabilitation of cancer patients: a review. Eur J Cancer 41(2):216–224CrossRefPubMed Kuhn K, Boesen E, Ross L, Johansen C (2005) Evaluation and outcome of behavioural changes in the rehabilitation of cancer patients: a review. Eur J Cancer 41(2):216–224CrossRefPubMed
42.
go back to reference Lubbe AS, Krischke NR, Dimeo F, Forkel S, Petermann F (2001) Health-related quality of life and pulmonary function in lung cancer patients undergoing medical rehabilitation treatment. Wien Med Wochenschr 151(1–2):29–34PubMed Lubbe AS, Krischke NR, Dimeo F, Forkel S, Petermann F (2001) Health-related quality of life and pulmonary function in lung cancer patients undergoing medical rehabilitation treatment. Wien Med Wochenschr 151(1–2):29–34PubMed
43.
go back to reference Luebbert K, Dahme B, Hasenbring M (2001) The effectiveness of relaxation training in reducing treatment-related symptoms and improving emotional adjustment in acute non-surgical cancer treatment: a meta-analytical review. Psychooncology 10(6):490–502PubMedCrossRef Luebbert K, Dahme B, Hasenbring M (2001) The effectiveness of relaxation training in reducing treatment-related symptoms and improving emotional adjustment in acute non-surgical cancer treatment: a meta-analytical review. Psychooncology 10(6):490–502PubMedCrossRef
44.
go back to reference MacVicar MG, Winningham ML, Nickel JL (1989) Effects of aerobic interval training on cancer patients’ functional capacity. Nurs Res 38(6):348–351PubMedCrossRef MacVicar MG, Winningham ML, Nickel JL (1989) Effects of aerobic interval training on cancer patients’ functional capacity. Nurs Res 38(6):348–351PubMedCrossRef
45.
go back to reference McKenzie DC, Kalda AL (2003) Effect of upper extremity exercise on secondary lymphedema in breast cancer patients: a pilot study. J Clin Oncol 21(3):463–466PubMedCrossRef McKenzie DC, Kalda AL (2003) Effect of upper extremity exercise on secondary lymphedema in breast cancer patients: a pilot study. J Clin Oncol 21(3):463–466PubMedCrossRef
46.
go back to reference Mock V (2004) Evidence-based treatment for cancer-related fatigue. J Natl Cancer Inst Monogr 32:112–118CrossRefPubMed Mock V (2004) Evidence-based treatment for cancer-related fatigue. J Natl Cancer Inst Monogr 32:112–118CrossRefPubMed
47.
go back to reference *Mock V, Burke MB, Sheehan P, Creaton EM, Winningham ML, McKenney-Tedder S, Schwager LP, Liebman M (1994) A nursing rehabilitation program for women with breast cancer receiving adjuvant chemotherapy. Oncol Nurs Forum 21(5):899–907PubMed *Mock V, Burke MB, Sheehan P, Creaton EM, Winningham ML, McKenney-Tedder S, Schwager LP, Liebman M (1994) A nursing rehabilitation program for women with breast cancer receiving adjuvant chemotherapy. Oncol Nurs Forum 21(5):899–907PubMed
48.
go back to reference Morris SB (2000) Distribution of the standardized mean change effect size for meta-analysis on repeated measures. Br J Math Stat Psychol 53:17–29PubMedCrossRef Morris SB (2000) Distribution of the standardized mean change effect size for meta-analysis on repeated measures. Br J Math Stat Psychol 53:17–29PubMedCrossRef
49.
go back to reference Morris SB, DeShon RP (2002) Combining effect size estimates in meta-analysis with repeated measures and independent-groups designs. Psychol Methods 2:105–125CrossRef Morris SB, DeShon RP (2002) Combining effect size estimates in meta-analysis with repeated measures and independent-groups designs. Psychol Methods 2:105–125CrossRef
50.
go back to reference *Nieman DC, Cook VD, Henson DA, Suttles J, Rejeski WJ, Ribisl PM, Fagoaga OR, Nehlsen-Cannarella SL (1995) Moderate exercise training and natural killer cell cytotoxic activity in breast cancer patients. Int J Sports Med 16(5):334–337PubMedCrossRef *Nieman DC, Cook VD, Henson DA, Suttles J, Rejeski WJ, Ribisl PM, Fagoaga OR, Nehlsen-Cannarella SL (1995) Moderate exercise training and natural killer cell cytotoxic activity in breast cancer patients. Int J Sports Med 16(5):334–337PubMedCrossRef
51.
go back to reference Nony P, Cucherat M, Haugh M, Boissell J (1995) Critical reading of the meta-analysis of clinical trials. Therapie 50:339–351PubMed Nony P, Cucherat M, Haugh M, Boissell J (1995) Critical reading of the meta-analysis of clinical trials. Therapie 50:339–351PubMed
52.
go back to reference Oldervoll LM, Kaasa S, Hjermstad MJ, Lund JA, Loge JH (2004) Physical exercise results in the improved subjective well-being of a few or is effective rehabilitation for all cancer patients? Eur J Cancer 40:951–962CrossRefPubMed Oldervoll LM, Kaasa S, Hjermstad MJ, Lund JA, Loge JH (2004) Physical exercise results in the improved subjective well-being of a few or is effective rehabilitation for all cancer patients? Eur J Cancer 40:951–962CrossRefPubMed
53.
go back to reference *Peters C, Lotzerich H, Niemeier B, Schule K, Uhlenbruck G (1994) Influence of a moderate exercise training on natural killer cytotoxicity and personality traits in cancer patients. Anticancer Res 14(3A):1033–1036PubMed *Peters C, Lotzerich H, Niemeier B, Schule K, Uhlenbruck G (1994) Influence of a moderate exercise training on natural killer cytotoxicity and personality traits in cancer patients. Anticancer Res 14(3A):1033–1036PubMed
54.
go back to reference *Pinto BM, Clark MM, Maruyama NC, Feder SI (2003) Psychological and fitness changes associated with exercise participation among women with breast cancer. Psychooncology 12(2):118–126PubMedCrossRef *Pinto BM, Clark MM, Maruyama NC, Feder SI (2003) Psychological and fitness changes associated with exercise participation among women with breast cancer. Psychooncology 12(2):118–126PubMedCrossRef
55.
go back to reference Porock D, Kristjanson L, Tinnelly K, Duke T, Blight J (2000) An exercise intervention for advanced cancer patients experiencing fatigue: a pilot study. J Palliat Care 16(3):30–36PubMed Porock D, Kristjanson L, Tinnelly K, Duke T, Blight J (2000) An exercise intervention for advanced cancer patients experiencing fatigue: a pilot study. J Palliat Care 16(3):30–36PubMed
56.
go back to reference Raudenbush SW (1994) Random effects models. In: Cooper H, Hedges L (eds) The handbook of research synthesis. Russell Sage Foundation, New York, pp 301–321 Raudenbush SW (1994) Random effects models. In: Cooper H, Hedges L (eds) The handbook of research synthesis. Russell Sage Foundation, New York, pp 301–321
57.
go back to reference Rock CL, Demark-Wahnefried W (2002) Can lifestyle modification increase survival in women diagnosed with breast cancer? J Nutr 132:3504S–3507SPubMed Rock CL, Demark-Wahnefried W (2002) Can lifestyle modification increase survival in women diagnosed with breast cancer? J Nutr 132:3504S–3507SPubMed
58.
go back to reference Schwartz AL, Thompson JA, Masood N (2002) Interferon-induced fatigue in patients with melanoma: a pilot study of exercise and methylphenidate. Oncol Nurs Forum 29(7):E85–E90PubMedCrossRef Schwartz AL, Thompson JA, Masood N (2002) Interferon-induced fatigue in patients with melanoma: a pilot study of exercise and methylphenidate. Oncol Nurs Forum 29(7):E85–E90PubMedCrossRef
59.
go back to reference *Segal R, Evans W, Johnson D, Smith J, Colletta S, Gayton J, Woodard S, Wells G, Reid R (2001) Structured exercise improves physical functioning in women with stages I and II breast cancer: results of a randomized controlled trial. J Clin Oncol 19(3):657–665PubMed *Segal R, Evans W, Johnson D, Smith J, Colletta S, Gayton J, Woodard S, Wells G, Reid R (2001) Structured exercise improves physical functioning in women with stages I and II breast cancer: results of a randomized controlled trial. J Clin Oncol 19(3):657–665PubMed
60.
go back to reference *Segal RJ, Reid RD, Courneya KS, Malone SC, Parliament MB, Scott CG, Venner PM, Quinney HA, Jones LW, D’Angelo ME, Wells GA (2003) Resistance exercise in men receiving androgen deprivation therapy for prostate cancer. J Clin Oncol 21(9):1653–1659PubMedCrossRef *Segal RJ, Reid RD, Courneya KS, Malone SC, Parliament MB, Scott CG, Venner PM, Quinney HA, Jones LW, D’Angelo ME, Wells GA (2003) Resistance exercise in men receiving androgen deprivation therapy for prostate cancer. J Clin Oncol 21(9):1653–1659PubMedCrossRef
61.
go back to reference Segar ML, Katch VL, Roth RS, Garcia AW, Portner TI, Glickman SG, Haslanger S, Wilkins EG (1998) The effect of aerobic exercise on self-esteem and depressive and anxiety symptoms among breast cancer survivors. Oncol Nurs Forum 25(1):107–113PubMed Segar ML, Katch VL, Roth RS, Garcia AW, Portner TI, Glickman SG, Haslanger S, Wilkins EG (1998) The effect of aerobic exercise on self-esteem and depressive and anxiety symptoms among breast cancer survivors. Oncol Nurs Forum 25(1):107–113PubMed
62.
go back to reference Servaes P, Verhagen C, Bleijenberg G (2002) Fatigue in cancer patients during and after treatment: prevalence, correlates and interventions. Eur J Cancer 38(1):27–43CrossRefPubMed Servaes P, Verhagen C, Bleijenberg G (2002) Fatigue in cancer patients during and after treatment: prevalence, correlates and interventions. Eur J Cancer 38(1):27–43CrossRefPubMed
63.
go back to reference Shadish W, Haddock C (1994) Combining estimates of effect size. In: Cooper H, Hedges L (eds) The handbook of research synthesis. Russell Sage Foundation, New York, pp 261–282 Shadish W, Haddock C (1994) Combining estimates of effect size. In: Cooper H, Hedges L (eds) The handbook of research synthesis. Russell Sage Foundation, New York, pp 261–282
64.
go back to reference Stone P (2002) The measurement, causes and effective management of cancer-related fatigue. Int J Palliat Nurs 8(3):120–128PubMed Stone P (2002) The measurement, causes and effective management of cancer-related fatigue. Int J Palliat Nurs 8(3):120–128PubMed
65.
go back to reference Stricker CT, Drake D, Hoyer KA, Mock V (2004) Evidence-based practice for fatigue management in adults with cancer: exercise as an intervention. Oncol Nurs Forum 31:963–974PubMedCrossRef Stricker CT, Drake D, Hoyer KA, Mock V (2004) Evidence-based practice for fatigue management in adults with cancer: exercise as an intervention. Oncol Nurs Forum 31:963–974PubMedCrossRef
66.
go back to reference Vevea JL, Hedges LV (1995) A general linear model for estimating effect size in the presence of publication bias. Psychometrika 60:419–435CrossRef Vevea JL, Hedges LV (1995) A general linear model for estimating effect size in the presence of publication bias. Psychometrika 60:419–435CrossRef
67.
go back to reference Watson T, Mock V (2004) Exercise as an intervention for cancer-related fatigue. Phys Ther 84:736–743PubMed Watson T, Mock V (2004) Exercise as an intervention for cancer-related fatigue. Phys Ther 84:736–743PubMed
68.
go back to reference Winningham ML, MacVicar MG (1988) The effect of aerobic exercise on patient reports of nausea. Oncol Nurs Forum 15(4):447–450PubMed Winningham ML, MacVicar MG (1988) The effect of aerobic exercise on patient reports of nausea. Oncol Nurs Forum 15(4):447–450PubMed
69.
go back to reference Zinna EM, Yarasheski KE (2003) Exercise treatment to counteract protein wasting of chronic diseases. Curr Opin Clin Nutr Metab Care 6(1):87–93CrossRefPubMed Zinna EM, Yarasheski KE (2003) Exercise treatment to counteract protein wasting of chronic diseases. Curr Opin Clin Nutr Metab Care 6(1):87–93CrossRefPubMed
Metadata
Title
A meta-analysis of exercise interventions among people treated for cancer
Authors
Vicki S. Conn
Adam R. Hafdahl
Davina C. Porock
Roxanne McDaniel
Paul J. Nielsen
Publication date
01-07-2006
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 7/2006
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-005-0905-5

Other articles of this Issue 7/2006

Supportive Care in Cancer 7/2006 Go to the issue

Forthcoming Meetings

Forthcoming Meetings

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine