Skip to main content
Top
Published in: Supportive Care in Cancer 2/2006

01-02-2006 | Original Article

Non-invasive ventilation for cancer patients with life-support techniques limitation

Authors: Anne-Pascale Meert, Thierry Berghmans, Michel Hardy, Eveline Markiewicz, Jean-Paul Sculier

Published in: Supportive Care in Cancer | Issue 2/2006

Login to get access

Abstract

Goals of work

The study was conducted to determine the usefulness and efficacy of non-invasive ventilation (NIV) in cancer patients with “life-support techniques limitation” admitted for an acute respiratory distress, in terms of intensive care unit (ICU) and hospital discharges.

Patients and methods

A total of 18 consecutive cancer patients (17 with solid tumours and one with haematological malignancy) with “life-support techniques limitation” in acute respiratory failure and who benefited from NIV were included. NIV was provided with a standard face mask by the BiPAP Vision ventilator (Respironics Inc.). Variables related to the demographic parameters, SAPS II score, cancer characteristics, intensive care data and hospital discharge were recorded.

Main results

Complications leading to NIV were hypoxemic respiratory failure in 11 patients and hypercapnic respiratory failure in seven. Total median duration of NIV was 29 h. NIV was applied during a median of 2.5 days with a median of 16 h per day. Total median ICU stay was 7 days (range 1–21). Fourteen and ten patients were discharged from ICU and from hospital, respectively.

Conclusion

NIV appears to be an effective ventilation support for cancer patients with “life-support techniques limitation”.
Literature
1.
go back to reference Brochard L, Mancebo J, Wysocki M, Lofaso F, Conti G, Rauss A, Simonneau G, Benito S, Gasparetto A, Lemaire F (1995) Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med 333:817–822CrossRefPubMed Brochard L, Mancebo J, Wysocki M, Lofaso F, Conti G, Rauss A, Simonneau G, Benito S, Gasparetto A, Lemaire F (1995) Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med 333:817–822CrossRefPubMed
2.
go back to reference Antonelli M, Conti G, Rocco M, Bufi M, De Blasi RA, Vivino G, Gasparetto A, Meduri GU (1998) A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure. N Engl J Med 339:429–435CrossRefPubMed Antonelli M, Conti G, Rocco M, Bufi M, De Blasi RA, Vivino G, Gasparetto A, Meduri GU (1998) A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure. N Engl J Med 339:429–435CrossRefPubMed
3.
go back to reference Meert AP, Close L, Hardy M, Berghmans T, Markiewicz E, Sculier JP (2003) Noninvasive ventilation: application to the cancer patient admitted in the intensive care unit. Support Care Cancer 11:56–59 Meert AP, Close L, Hardy M, Berghmans T, Markiewicz E, Sculier JP (2003) Noninvasive ventilation: application to the cancer patient admitted in the intensive care unit. Support Care Cancer 11:56–59
4.
go back to reference American Thoracic Society (2001) International Consensus Conference in Intensive Care Medicine: noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med 163:283–291 American Thoracic Society (2001) International Consensus Conference in Intensive Care Medicine: noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med 163:283–291
5.
go back to reference British Thoracic Society Standards of Care Committee (2002) Non-invasive ventilation in acute respiratory failure. Thorax 57:192–211 British Thoracic Society Standards of Care Committee (2002) Non-invasive ventilation in acute respiratory failure. Thorax 57:192–211
6.
go back to reference Chu C, Chan V, Wong I, Leung W, Lin A, Cheung K (2004) Noninvasive ventilation in patients with acute hypercapnic exacerbation of chronic obstructive pulmonary disease who refused endotracheal intubation. Crit Care Med 32:372–377CrossRefPubMed Chu C, Chan V, Wong I, Leung W, Lin A, Cheung K (2004) Noninvasive ventilation in patients with acute hypercapnic exacerbation of chronic obstructive pulmonary disease who refused endotracheal intubation. Crit Care Med 32:372–377CrossRefPubMed
7.
go back to reference Meduri GU, Fox RC, Abou-Shala N, Leeper KV, Wunderink RG (1994) Noninvasive mechanical ventilation via face mask in patients with acute respiratory failure who refused endotracheal intubation. Crit Care Med 22:1584–1590PubMed Meduri GU, Fox RC, Abou-Shala N, Leeper KV, Wunderink RG (1994) Noninvasive mechanical ventilation via face mask in patients with acute respiratory failure who refused endotracheal intubation. Crit Care Med 22:1584–1590PubMed
8.
go back to reference Benhamou D, Girault C, Faure C, Portier F, Muir JF (1992) Nasal mask ventilation in acute respiratory failure. Experience in elderly patients. Chest 102:912–917PubMed Benhamou D, Girault C, Faure C, Portier F, Muir JF (1992) Nasal mask ventilation in acute respiratory failure. Experience in elderly patients. Chest 102:912–917PubMed
9.
go back to reference Levy M, Tanios MA, Nelson D, Short K, Senechia A, Vespia J, Hill NS (2004) Outcomes of patients with do-not-intubate orders treated with noninvasive ventilation. Crit Care Med 32:2002–2007CrossRefPubMed Levy M, Tanios MA, Nelson D, Short K, Senechia A, Vespia J, Hill NS (2004) Outcomes of patients with do-not-intubate orders treated with noninvasive ventilation. Crit Care Med 32:2002–2007CrossRefPubMed
10.
go back to reference Cuomo A, Delmastro M, Ceriana P, Nava S, Conti G, Antonelli M, Iacobone E (2004) Noninvasive mechanical ventilation as a palliative treatment of acute respiratory failure in patients with end-stage solid cancer. Palliat Med 18:602–610CrossRefPubMed Cuomo A, Delmastro M, Ceriana P, Nava S, Conti G, Antonelli M, Iacobone E (2004) Noninvasive mechanical ventilation as a palliative treatment of acute respiratory failure in patients with end-stage solid cancer. Palliat Med 18:602–610CrossRefPubMed
11.
go back to reference Haines IE, Zalcberg J, Buchanan JD (1990) Not-for-resuscitation orders in cancer patients—principles of decision-making. Med J Aust 153:225–229PubMed Haines IE, Zalcberg J, Buchanan JD (1990) Not-for-resuscitation orders in cancer patients—principles of decision-making. Med J Aust 153:225–229PubMed
12.
go back to reference Le Gall JR, Lemeshow S, Saulnier F (1993) A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 270:2957–2963PubMed Le Gall JR, Lemeshow S, Saulnier F (1993) A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 270:2957–2963PubMed
13.
go back to reference Meduri GU, Turner RE, Abou-Shala N, Wunderink R, Tolley E (1996) Noninvasive positive pressure ventilation via face mask. First-line intervention in patients with acute hypercapnic and hypoxemic respiratory failure. Chest 109:179–193PubMed Meduri GU, Turner RE, Abou-Shala N, Wunderink R, Tolley E (1996) Noninvasive positive pressure ventilation via face mask. First-line intervention in patients with acute hypercapnic and hypoxemic respiratory failure. Chest 109:179–193PubMed
14.
go back to reference Sculier JP, Paesmans M, Markiewicz E, Berghmans T (2000) Scoring systems in cancer patients admitted for an acute complication in a medical intensive care unit. Crit Care Med 28:2786–2792CrossRefPubMed Sculier JP, Paesmans M, Markiewicz E, Berghmans T (2000) Scoring systems in cancer patients admitted for an acute complication in a medical intensive care unit. Crit Care Med 28:2786–2792CrossRefPubMed
15.
go back to reference Berghmans T, Paesmans M, Sculier JP (2004) Is a specific oncological scoring system better at predicting the prognosis of cancer patients admitted for an acute medical complication in an intensive care unit than general gravity scores? Support Care Cancer 12:234–239 Berghmans T, Paesmans M, Sculier JP (2004) Is a specific oncological scoring system better at predicting the prognosis of cancer patients admitted for an acute medical complication in an intensive care unit than general gravity scores? Support Care Cancer 12:234–239
Metadata
Title
Non-invasive ventilation for cancer patients with life-support techniques limitation
Authors
Anne-Pascale Meert
Thierry Berghmans
Michel Hardy
Eveline Markiewicz
Jean-Paul Sculier
Publication date
01-02-2006
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 2/2006
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-005-0845-0

Other articles of this Issue 2/2006

Supportive Care in Cancer 2/2006 Go to the issue
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine