Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Supportive Care in Cancer
Published in: Supportive Care in Cancer 5/2004

01-05-2004 | Original Article

Assessment of peri-operative quality of life in patients undergoing surgery for gastrointestinal cancer

Authors: Toshiko Matsushita, Eisuke Matsushima, Michio Maruyama

Published in: Supportive Care in Cancer | Issue 5/2004

Login to get access

Abstract

The purpose of this study was to assess the pre- and postoperative quality of life (QOL) of patients with gastrointestinal cancer and to investigate the relationship between QOL and various psychological and clinical factors. Eighty-five patients who underwent surgery for gastrointestinal cancer and 26 control patients undergoing surgery for digestive diseases other than cancer were interviewed. Two tests were administered to assess QOL and psychological status respectively: the Japanese-language version of the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and the Japanese-language version of the Hospital Anxiety and Depression Scale (HADS). Each test was administered before surgery, before discharge, and 6 months after discharge. Gastrointestinal tumors were localized to the stomach, colon, or rectum in 88% of cases and classified as advanced stage or early stage according to staging protocols. Changes in EORTC QLQ-C30 subscale scores over time were compared among advanced stage, early stage, and control patients. All groups showed significant changes in subscale scores of QOL; the scores of the advanced-stage group indicated worse QOL than the early-stage and control groups in a lot of areas. The physical function (PF2) QOL subscore was influenced by diagnosis, postoperative complications, medical equipment at discharge, and the length of admission and negatively correlated with depression and anxiety. These results suggest that QOL in gastrointestinal cancer patients is variable over time and is influenced by various clinical factors. Therefore, consideration of these clinical factors is paramount to the optimal care of gastrointestinal cancer patients.
Literature
1.
Aaronson NK, Ahmedzai S, Bergman B, et al (1993)The European Organization for Research and Treatment of Cancer QLQ-30; A quality-of-life instrument of use in international clinical trials in oncology. Journal of the National Cancer Institute 85:365–376CrossRefPubMed
2.
Andrew Bottomley (2001) Developing clinical trial protocols for quality of life assessment. Applied Clinical Trials January: 1–5
3.
Brunelli C, Mosconi P, Boeri P, et al (2000) Evaluation of quality of life in patients with malignant dysphagia. Tumori 86:134–138PubMed
4.
5.
Coates A, Porzsolt F, Osoba D (1997) Quality of life in oncology practice: prognostic value of EORTC QOL-30 scores in patients with advanced malignancy. Euro J Cancer 33:1025–1030CrossRef
6.
Doyle C,Crump M,Pintilie M,Oza AM (2001) Does palliative chemotherapy palliate? Evaluation of expectations, outcomes, and costs in women receiving chemotherapy for advanced ovarian cancer. J Clin Oncol 19:1266–1274PubMed
7.
Earlam S, Glover C, Fordy C, Burke D, Allen-Mersh TG (1996) Relation between tumor size, quality of life, and survival in patients with colorectal liver metastases. J Clin Oncol 14:171–175PubMed
8.
Folstein M, Folstein S, McHugh P (1975) “MINI-MENTAL STATE” A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189–198PubMed
9.
Forsberg C, Cedermark B (1996) Well-being, general health and coping ability: 1-year follow-up of patients treated for colorectal and gastric cancer. Eur J Cancer Care 5:209–216
10.
Forsberg C, Bjorvell H, Cedermark B (1996) Well-being and its relation to coping ability in patients with colo-rectal and gastric cancer before and after surgery. Scand J caring Sci 10:35–44
11.
Ganz PA, Lee JJ, Siau J (1991) Quality of life assessment: an independent prognostic variable for survival in lung cancer. Cancer 67:3131–3135PubMed
12.
Greimel E, Thiel I, Peintinger F, Cegnar I, Pongratz E (2002) Prospective assessment of quality of life of female cancer patients. Gynecol Oncol 85:140–147CrossRefPubMed
13.
Halford S, Yip D, Karapetis CS, et al (2001) A phase II study evaluating the tolerability and efficacy of CAELYX (liposomal doxorubicin, Doxil) in the treatment of unresectable pancreatic carcinoma. Ann Oncol 12:1399–1402CrossRefPubMed
14.
Hasegawa S, Nakayama K, Utsunomiya K (2001) Journal of Health and Welfare Statistics. Health and Welfare Statistics Association, Tokyo, pp 48–54
15.
Hasegawa S, Nakayama K, Utsunomiya K (2001) Journal of Health and Welfare Statistics. Health and Welfare Statistics Association, Tokyo, pp 451–455
16.
Herrmann C (1997) International experiences with the hospital anxiety and depression scale a review of validation data and clinical results. J Psycho Res 42:17–41CrossRef
17.
Hosaka T, Aoki T.(1996) Depression among cancer patients. Psychiatry Clin Neurosci 50:309–312PubMed
18.
Japanese Colon Cancer Association (2001) Colon cancer treatment guidelines, Tokyo
19.
Japanese Esophageal Cancer Association (2001) Esophageal cancer treatment guidelines, Tokyo
20.
Japanese Gastric Cancer Association (2001) The first version of gastric cancer treatment guidelines, Tokyo
21.
Japanese Pancreas Cancer Association (2001) Pancreas cancer treatment guidelines, Tokyo
22.
Johnston M, Pollard B, Hennessey P (2000) Construct validation of the hospital anxiety and depression scale with clinical populations. J Psychosom Res 48:579–584CrossRefPubMed
23.
Kelsen DP, Portenoy RK, Thaler HT, et al (1995) Pain and depression in patients with newly diagnosed pancreas cancer. J Clin Oncol 13:748–755PubMed
24.
Kenn C, Wood H, Kucyj M (1987) Validation of the Hospital Anxiety and Depression Rating Scale (HADS) in a elderly psychiatric population. Int J Ger Psychiatry 2:189–193
25.
Kobayashi K, Takeda F, Teramukai S, et al (1998) A cross-validation of the European Organization for Research and Treatment of cancer QLQ-C30 (EORTC QLQ-C30) for Japanese with lung cancer. Eur J Cancer 34:810–815CrossRefPubMed
26.
Kono K, Iizuka H, Sekikawa T, et al (2003) Improved quality of life with jejunal pouch reconstruction after total gastrectomy. Am J Surg 185:150-154CrossRefPubMed
27.
Matsushima E (2002) The study of psycho-oncology in a general surgical ward. Health welfare scientific research “The study of palliative care & psycho-oncology in cancer treatment” 39–40 (in Japanese)
28.
Norum J, Balteskard L, Edna TH, Laino R, Wahlby L, Ronning G (2002) Ralitrexed (Tomudex) or Nordic-FLv regimen in metastatic colorectal cancer: a randomized phase II study focusing on quality of life, patients’ preferences and health economics. J Chemother 14:301–308PubMed
29.
Ouchi K, Sugawara T, Ono H, et al (1998) Therapeutic significance of palliative operations for gastric cancer for survival and quality of life. J Surg Oncol 69:41–44CrossRefPubMed
30.
Ouchi K, Sugawara T, Ono H, et al (1998) Palliative operation for cancer of the head of the pancreas: significance of pancreaticoduodenectomy and intraoperative radiation therapy for survival and quality of life. World J Surg 22:413–416CrossRefPubMed
31.
Padilla GV, Grant MM, Lipsett J, Anderson PR, Rhiner M, Bogen C (1992) Health quality of life and colo-rectal cancer. Cancer Suppl 70:1450–1456
32.
Portenoy RK, Thaler HT, Kornblith AB, et al (1994) Symptom prevalence, characteristics and distress in a cancer population. Qual Life Res 3:183–189PubMed
33.
Ringdal GI, Ringdal K, Kvinnsland S, Gotestam KG (1994) Quality of life of cancer patients with different prognoses. Qual Life Res 3:143–154PubMed
34.
Shimozuma K, Katsumata N, Ohashi Y, Makino H, Takashima S, Sonoo H (1999) Impact of surgical adjuvant chemotherapy on quality of life (QOL) of patients with breast cancer (BC)-A phase randomized trial comparing UFT(Uracil/Tegafur)with CMF in high-risk node negative patients. Proceeding of 35th Annual Meeting of ASCO, pp 579a
35.
Spector NM, Hicks FD, Pickleman J (2002) Quality of life and symptoms after surgery for gastroesophageal cancer: a pilot study. Gastroenterol Nurs 25:120–125CrossRefPubMed
36.
Sprangers MA, Cull A, Bjordal K, Groenvold M, Aaronson NK (1993) The European Organization for Research and Treatment of Cancer approach to quality of life assessment: guideline for developing questionnaire modules. Qual Life Res 2:287–295PubMed
37.
Von Essen L, Larsson G, Oberg K, Sjoden PO (2002) “Satisfaction with care”: associations with health-related quality of life and psychosocial function among Swedish patients with endocrine gastrointestinal tumors. Eur J Cancer Care 11:91–99CrossRef
38.
Williams NS, Johnston D (1983) The quality of life after rectal excision for low rectal cancer. Br J Surg 70:460–462PubMed
39.
Wu CW, Lo SS, Shen KH, Hsieh MC, Lui WY, P’eng FK (2000) Surgical mortality, survival, and quality of life after resection for gastric cancer in the elderly. World J Surg 24:465–472CrossRefPubMed
40.
Yasue M, Sakamoto J, Morimoto T, et al (1995) Evaluation of the effect of pancreatic resection in advanced pancreatic cancer with special reference using hospital-free survival as a measure of quality of life. Jpn J Clin Oncol 25:37–45PubMed
41.
Zigmond AS, Snaith RP (1983) The Hospital Anxiety and Depression Scale. Acta Psychiatr Scand 67:361–370PubMed
42.
Zigmond AS, Snaith RP, Kitamura translation (1993) Hospital Anxiety and Depression Scale (HAD Scale) (in Japanese). Archives of Psychiatric Diagnostics and Clinical Evaluation 4:371–372
Metadata
Title
Assessment of peri-operative quality of life in patients undergoing surgery for gastrointestinal cancer
Authors
Toshiko Matsushita
Eisuke Matsushima
Michio Maruyama
Publication date
01-05-2004
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 5/2004
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-004-0618-1

Other articles of this Issue 5/2004

Supportive Care in Cancer 5/2004 Go to the issue

Original Article

Cancer supportive care, improving the quality of life for cancer patients. A program evaluation report

Original Article

Off-label prescribing in oncology

Original Article

A qualitative study of head and neck cancer

Forthcoming Meetings

May 2004

Supportive Care International

Why Taiwanese hospice patients want to stay in hospital: health-care professionals’ beliefs and solutions

Original Article

Cancer-specific social support received by newly diagnosed cancer patients: validating the new Structural-Functional Social Support Scale (SFSS) measurement tool
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Watch now

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
Image Credits