Skip to main content
Top
Published in: Pediatric Nephrology 4/2021

01-04-2021 | Lung Ultrasound | Original Article

Lung ultrasound methods for assessing fluid volume change and monitoring dry weight in pediatric hemodialysis patients

Authors: Qian Fu, Zhi Chen, Jianfeng Fan, Chen Ling, Xiaoman Wang, Xiaorong Liu, Ying Shen

Published in: Pediatric Nephrology | Issue 4/2021

Login to get access

Abstract

Background

The value of lung ultrasound in adult hemodialysis has been confirmed. The determination of dry weight in children remains challenging. This study explores the usefulness of lung ultrasound in assessing fluid volume change and the possibility of pulmonary ultrasound as a method to monitor dry weight in pediatric dialysis patients.

Methods

This was a prospective observational study. We compared the predialysis and postdialysis B-line scores of the dry-weight group and non-dry-weight group. Changes in body weight and B-line scores were recorded during the dialytic period and interdialytic period, and the correlation was analyzed. Lung ultrasound was performed after the dialysis session every Friday, and B-line score < 10 was considered to indicate that there was no volume overload; the weight was recorded as the target weight.

Results

Fourteen patients were included. A total of 78 ultrasound assessments were performed: 30 in the dry-weight group and 48 in the non-dry-weight group. The B-line scores decreased after dialysis in all patients (p < 0.001). Thirty-three assessments were performed in the interdialytic period, and 40 assessments in the dialytic period were performed within 1 week. Linear regression showed that changes in B-line number were directly and positively correlated with interdialytic weight gain (r = 0.517, p = 0.002) and dialytic weight loss (r = 0.558, p < 0.001). The weight of the children increased gradually without volume overload in two patients during follow-up.

Conclusion

Lung ultrasound can assess the fluid volume change of pediatric dialysis patients in real time. Lung ultrasound could be a valuable method for monitoring dry weight in pediatric dialysis patients.
Literature
1.
go back to reference Sinha AD, Agarwal R (2009) Can chronic volume overload be recognized and prevented in hemodialysis patients? The pitfalls of the clinical examination in assessing volume status. Semin Dial 22:480–482CrossRef Sinha AD, Agarwal R (2009) Can chronic volume overload be recognized and prevented in hemodialysis patients? The pitfalls of the clinical examination in assessing volume status. Semin Dial 22:480–482CrossRef
2.
go back to reference Hecking M, Rayner H, Wabel P (2015) What are the consequences of volume expansion in chronic dialysis patients?: defining and measuring fluid overload in hemodialysis patients. Semin Dial 28:242–247CrossRef Hecking M, Rayner H, Wabel P (2015) What are the consequences of volume expansion in chronic dialysis patients?: defining and measuring fluid overload in hemodialysis patients. Semin Dial 28:242–247CrossRef
3.
go back to reference Charra B, Laurent G, Chazot C, Calemard E, Terrat JC, Vanel T, Jean G, Ruffet M (1996) Clinical assessment of dry weight. Nephrol Dial Transplant 11:16–19CrossRef Charra B, Laurent G, Chazot C, Calemard E, Terrat JC, Vanel T, Jean G, Ruffet M (1996) Clinical assessment of dry weight. Nephrol Dial Transplant 11:16–19CrossRef
4.
go back to reference Torino C, Gargani L, Sicari R, Letachowicz K, Ekart R, Fliser D, Covic A, Siamopoulos K, Stavroulopoulos A, Massy ZA, Fiaccadori E, Caiazza A, Bachelet T, Slotki I, Martinez-Castelao A, Coudert-Krier MJ, Rossignol P, Gueler F, Hannedouche T, Panichi V, Wiecek A, Pontoriero G, Sarafidis P, Klinger M, Hojs R, Seiler-Mussler S, Lizzi F, Siriopol D, Balafa O, Shavit L, Tripepi R, Mallamaci F, Tripepi G, Picano E, London GM, Zoccali C (2016) The agreement between auscultation and lung ultrasound in hemodialysis patients: the LUST study. Clin J Am Soc Nephrol 11:2005–2011CrossRef Torino C, Gargani L, Sicari R, Letachowicz K, Ekart R, Fliser D, Covic A, Siamopoulos K, Stavroulopoulos A, Massy ZA, Fiaccadori E, Caiazza A, Bachelet T, Slotki I, Martinez-Castelao A, Coudert-Krier MJ, Rossignol P, Gueler F, Hannedouche T, Panichi V, Wiecek A, Pontoriero G, Sarafidis P, Klinger M, Hojs R, Seiler-Mussler S, Lizzi F, Siriopol D, Balafa O, Shavit L, Tripepi R, Mallamaci F, Tripepi G, Picano E, London GM, Zoccali C (2016) The agreement between auscultation and lung ultrasound in hemodialysis patients: the LUST study. Clin J Am Soc Nephrol 11:2005–2011CrossRef
5.
go back to reference Lichtenstein D, Mézière G, Biderman P, Gepner A, Barré O (1997) The comet-tail artifact. An ultrasound sign of alveolar-interstitial syndrome. Am J Respir Crit Care Med 156:1640–1646CrossRef Lichtenstein D, Mézière G, Biderman P, Gepner A, Barré O (1997) The comet-tail artifact. An ultrasound sign of alveolar-interstitial syndrome. Am J Respir Crit Care Med 156:1640–1646CrossRef
6.
go back to reference Noble VE, Murray AF, Capp R, Sylvia-Reardon MH, Steele DJR, Liteplo A (2009) Ultrasound assessment for extravascular lung water in patients undergoing hemodialysis. Time course for resolution. Chest 135:1433–1439CrossRef Noble VE, Murray AF, Capp R, Sylvia-Reardon MH, Steele DJR, Liteplo A (2009) Ultrasound assessment for extravascular lung water in patients undergoing hemodialysis. Time course for resolution. Chest 135:1433–1439CrossRef
7.
go back to reference Vitturi N, Dugo M, Soattin M, Simoni F, Maresca L, Zagatti R, Maresca MC (2014) Lung ultrasound during hemodialysis: the role in the assessment of volume status. Int Urol Nephrol 46:169–174CrossRef Vitturi N, Dugo M, Soattin M, Simoni F, Maresca L, Zagatti R, Maresca MC (2014) Lung ultrasound during hemodialysis: the role in the assessment of volume status. Int Urol Nephrol 46:169–174CrossRef
8.
go back to reference Panuccio V, Enia G, Tripepi R, Torino C, Garozzo M, Battaglia GG, Marcantoni C, Infantone L, Giordano G, De Giorgi ML, Lupia M, Bruzzese V, Zoccali C (2012) Chest ultrasound and hidden lung congestion in peritoneal dialysis patients. Nephrol Dial Transplant 27:3601–3605CrossRef Panuccio V, Enia G, Tripepi R, Torino C, Garozzo M, Battaglia GG, Marcantoni C, Infantone L, Giordano G, De Giorgi ML, Lupia M, Bruzzese V, Zoccali C (2012) Chest ultrasound and hidden lung congestion in peritoneal dialysis patients. Nephrol Dial Transplant 27:3601–3605CrossRef
9.
go back to reference Basso F, Milan Manani S, Cruz DN, Teixeira C, Brendolan A, Nalesso F, Zanella M, Ronco C (2013) Comparison and reproducibility of techniques for fluid status assessment in chronic hemodialysis patients. Cardiorenal Med 3:104–112CrossRef Basso F, Milan Manani S, Cruz DN, Teixeira C, Brendolan A, Nalesso F, Zanella M, Ronco C (2013) Comparison and reproducibility of techniques for fluid status assessment in chronic hemodialysis patients. Cardiorenal Med 3:104–112CrossRef
10.
go back to reference Donadio C, Bozzoli L, Colombini E, Pisanu G, Ricchiuti G, Picano E, Gargani L (2015) Effective and timely evaluation of pulmonary congestion: qualitative comparison between lung ultrasound and thoracic bioelectrical impedance in maintenance hemodialysis patients. Medicine (Baltimore) 94:e473CrossRef Donadio C, Bozzoli L, Colombini E, Pisanu G, Ricchiuti G, Picano E, Gargani L (2015) Effective and timely evaluation of pulmonary congestion: qualitative comparison between lung ultrasound and thoracic bioelectrical impedance in maintenance hemodialysis patients. Medicine (Baltimore) 94:e473CrossRef
11.
go back to reference Allinovi M, Saleem M, Romagnani P, Nazerian P, Hayes W (2017) Lung ultrasound: a novel technique for detecting fluid overload in children on dialysis. Nephrol Dial Transplant 32:541–547PubMed Allinovi M, Saleem M, Romagnani P, Nazerian P, Hayes W (2017) Lung ultrasound: a novel technique for detecting fluid overload in children on dialysis. Nephrol Dial Transplant 32:541–547PubMed
12.
go back to reference Allinovi M, Saleem MA, Burgess O, Armstrong C, Hayes W (2016) Finding covert fluid: methods for detecting volume overload in children on dialysis. Pediatr Nephrol 31:2327–2335CrossRef Allinovi M, Saleem MA, Burgess O, Armstrong C, Hayes W (2016) Finding covert fluid: methods for detecting volume overload in children on dialysis. Pediatr Nephrol 31:2327–2335CrossRef
13.
go back to reference Volpicelli G, Mussa A, Garofalo G, Cardinale L, Casoli G, Perotto F, Fava C, Frascisco M (2006) Bedside lung ultrasound in the assessment of alveolar-interstitial syndrome. Am J Emerg Med 24:689–696CrossRef Volpicelli G, Mussa A, Garofalo G, Cardinale L, Casoli G, Perotto F, Fava C, Frascisco M (2006) Bedside lung ultrasound in the assessment of alveolar-interstitial syndrome. Am J Emerg Med 24:689–696CrossRef
14.
go back to reference Jambrik Z, Monti S, Coppola V, Agricola E, Mottola G, Miniati M, Picano E (2004) Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water. Am J Cardiol 93:1265–1270CrossRef Jambrik Z, Monti S, Coppola V, Agricola E, Mottola G, Miniati M, Picano E (2004) Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water. Am J Cardiol 93:1265–1270CrossRef
15.
go back to reference Dietrich CF, Mathis G, Blaivas M, Volpicelli G, Seibel A, Wastl D, Atkinson NSS, Cui XW, Fan M, Yi D (2016) Lung B-line artefacts and their use. J Thorac Dis 8:1356–1365CrossRef Dietrich CF, Mathis G, Blaivas M, Volpicelli G, Seibel A, Wastl D, Atkinson NSS, Cui XW, Fan M, Yi D (2016) Lung B-line artefacts and their use. J Thorac Dis 8:1356–1365CrossRef
16.
go back to reference Hasan AA, Makhlouf HA (2014) B-lines: transthoracic chest ultrasound signs useful in assessment of interstitial lung diseases. Ann Thorac Med 9:99–103CrossRef Hasan AA, Makhlouf HA (2014) B-lines: transthoracic chest ultrasound signs useful in assessment of interstitial lung diseases. Ann Thorac Med 9:99–103CrossRef
17.
go back to reference Soldati G, Copetti R, Sher S (2009) Sonographic interstitial syndrome: the sound of lung water. J Ultrasound Med 28:163–174CrossRef Soldati G, Copetti R, Sher S (2009) Sonographic interstitial syndrome: the sound of lung water. J Ultrasound Med 28:163–174CrossRef
18.
go back to reference Flynn JT, Kaelber DC, Baker-Smith CM, Blowey D, Carroll AE, Daniels SR, de Ferranti SD, Dionne JM, Falkner B, Flinn SK, Gidding SS, Goodwin C, Leu MG, Powers ME, Rea C, Samuels J, Simasek M, Thaker VV, Urbina EM, SUBCOMMITTEE ON SCREENING AND MANAGEMENT OF HIGH BLOOD PRESSURE IN CHILDREN (2017) Clinical practice guideline for screening and management of high blood pressure in children and adolescents. Pediatrics. 140:e20171904CrossRef Flynn JT, Kaelber DC, Baker-Smith CM, Blowey D, Carroll AE, Daniels SR, de Ferranti SD, Dionne JM, Falkner B, Flinn SK, Gidding SS, Goodwin C, Leu MG, Powers ME, Rea C, Samuels J, Simasek M, Thaker VV, Urbina EM, SUBCOMMITTEE ON SCREENING AND MANAGEMENT OF HIGH BLOOD PRESSURE IN CHILDREN (2017) Clinical practice guideline for screening and management of high blood pressure in children and adolescents. Pediatrics. 140:e20171904CrossRef
19.
go back to reference KDOQI Work Group (2009) KDOQI clinical practice guideline for nutrition in children with CKD: 2008 update. Executive summary. Am J Kidney Dis 53(3 Suppl 2):S11–S104 KDOQI Work Group (2009) KDOQI clinical practice guideline for nutrition in children with CKD: 2008 update. Executive summary. Am J Kidney Dis 53(3 Suppl 2):S11–S104
20.
go back to reference Agricola E, Bove T, Oppizzi M, Marino G, Zangrillo A, Margonato A, Picano E (2005) “Ultrasound comet-tail images”: a marker of pulmonary edema: a comparative study with wedge pressure and extravascular lung water. Chest 127:1690–1695CrossRef Agricola E, Bove T, Oppizzi M, Marino G, Zangrillo A, Margonato A, Picano E (2005) “Ultrasound comet-tail images”: a marker of pulmonary edema: a comparative study with wedge pressure and extravascular lung water. Chest 127:1690–1695CrossRef
21.
go back to reference Liang XK, Li LJ, Wang XH, Wang XX, Wang YD, Xu ZF (2019) Role of lung ultrasound in adjusting ultrafiltration volume in hemodialysis patients. Ultrasound Med Biol 45:732–740CrossRef Liang XK, Li LJ, Wang XH, Wang XX, Wang YD, Xu ZF (2019) Role of lung ultrasound in adjusting ultrafiltration volume in hemodialysis patients. Ultrasound Med Biol 45:732–740CrossRef
22.
go back to reference Covic A, Siriopol D, Voroneanu L (2018) Use of lung ultrasound for the assessment of volume status in CKD. Am J Kidney Dis 71:412–422CrossRef Covic A, Siriopol D, Voroneanu L (2018) Use of lung ultrasound for the assessment of volume status in CKD. Am J Kidney Dis 71:412–422CrossRef
23.
go back to reference Arun Thomas ET, Mohandas MK, George J (2019) Comparison between clinical judgment and integrated lung and inferior vena cava ultrasonography for dry weight estimation in hemodialysis patients. Hemodial Int 23:494–503CrossRef Arun Thomas ET, Mohandas MK, George J (2019) Comparison between clinical judgment and integrated lung and inferior vena cava ultrasonography for dry weight estimation in hemodialysis patients. Hemodial Int 23:494–503CrossRef
24.
go back to reference Loutradis C, Sarafidis PA, Ekart R, Papadopoulos C, Sachpekidis V, Alexandrou ME, Papadopoulou D, Efstratiadis G, Papagianni A, London G, Zoccali C (2019) The effect of dry-weight reduction guided by lung ultrasound on ambulatory blood pressure in hemodialysis patients: a randomized controlled trial. Kidney Int 95:1505–1513CrossRef Loutradis C, Sarafidis PA, Ekart R, Papadopoulos C, Sachpekidis V, Alexandrou ME, Papadopoulou D, Efstratiadis G, Papagianni A, London G, Zoccali C (2019) The effect of dry-weight reduction guided by lung ultrasound on ambulatory blood pressure in hemodialysis patients: a randomized controlled trial. Kidney Int 95:1505–1513CrossRef
25.
go back to reference Haskin O, Wong CJ, McCabe L, Begin B, Sutherland SM, Chaudhuri A (2015) 44-h ambulatory blood pressure monitoring: revealing the true burden of hypertension in pediatric hemodialysis patients. Pediatr Nephrol 30:653–665CrossRef Haskin O, Wong CJ, McCabe L, Begin B, Sutherland SM, Chaudhuri A (2015) 44-h ambulatory blood pressure monitoring: revealing the true burden of hypertension in pediatric hemodialysis patients. Pediatr Nephrol 30:653–665CrossRef
26.
go back to reference VanDeVoorde RG, Barletta GM, Chand DH, Dresner IG, Lane J, Leiser J, Lin JJ, Pan CG, Patel H, Valentini RP, Mitsnefes MM (2007) Blood pressure control in pediatric hemodialysis: the Midwest pediatric nephrology consortium study. Pediatr Nephrol 22:547–553CrossRef VanDeVoorde RG, Barletta GM, Chand DH, Dresner IG, Lane J, Leiser J, Lin JJ, Pan CG, Patel H, Valentini RP, Mitsnefes MM (2007) Blood pressure control in pediatric hemodialysis: the Midwest pediatric nephrology consortium study. Pediatr Nephrol 22:547–553CrossRef
27.
go back to reference Paglialonga F, Consolo S, Edefonti A, Montini G (2018) Blood pressure management in children on dialysis. Pediatr Nephrol 33:239–250CrossRef Paglialonga F, Consolo S, Edefonti A, Montini G (2018) Blood pressure management in children on dialysis. Pediatr Nephrol 33:239–250CrossRef
28.
go back to reference Paglialonga F, Consolo S, Galli MA, Testa S, Edefonti A (2015) Interdialytic weight gain in oligoanuric children and adolescents on chronic hemodialysis. Pediatr Nephrol 30:999–1005CrossRef Paglialonga F, Consolo S, Galli MA, Testa S, Edefonti A (2015) Interdialytic weight gain in oligoanuric children and adolescents on chronic hemodialysis. Pediatr Nephrol 30:999–1005CrossRef
29.
go back to reference Hayes W, Paglialonga F (2019) Assessment and management of fluid overload in children on dialysis. Pediatr Nephrol 34:233–242CrossRef Hayes W, Paglialonga F (2019) Assessment and management of fluid overload in children on dialysis. Pediatr Nephrol 34:233–242CrossRef
30.
go back to reference Marsenic O, Anderson M, Couloures KG (2016) Relationship between interdialytic weight gain and blood pressure in pediatric patients on chronic hemodialysis. Biomed Res Int 2016:5972930CrossRef Marsenic O, Anderson M, Couloures KG (2016) Relationship between interdialytic weight gain and blood pressure in pediatric patients on chronic hemodialysis. Biomed Res Int 2016:5972930CrossRef
31.
go back to reference Fischbach M, Edefonti A, Schröder C, Watson A, European Pediatric Dialysis Working Group (2005) Hemodialysis in children: general practical guidelines. Pediatr Nephrol 20:1054–1066CrossRef Fischbach M, Edefonti A, Schröder C, Watson A, European Pediatric Dialysis Working Group (2005) Hemodialysis in children: general practical guidelines. Pediatr Nephrol 20:1054–1066CrossRef
32.
go back to reference Agarwal R, Toto RD, Weir MR (2020) Extravascular lung water assessment by ultrasound to guide dry weight changes: ready for prime time? Am J Kidney Dis 75:1–3CrossRef Agarwal R, Toto RD, Weir MR (2020) Extravascular lung water assessment by ultrasound to guide dry weight changes: ready for prime time? Am J Kidney Dis 75:1–3CrossRef
Metadata
Title
Lung ultrasound methods for assessing fluid volume change and monitoring dry weight in pediatric hemodialysis patients
Authors
Qian Fu
Zhi Chen
Jianfeng Fan
Chen Ling
Xiaoman Wang
Xiaorong Liu
Ying Shen
Publication date
01-04-2021
Publisher
Springer Berlin Heidelberg
Keyword
Lung Ultrasound
Published in
Pediatric Nephrology / Issue 4/2021
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-020-04735-9

Other articles of this Issue 4/2021

Pediatric Nephrology 4/2021 Go to the issue