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01-11-2014 | Original Article

Ambulatory blood pressure monitoring is recommended in the clinical management of children with a solitary functioning kidney

Authors: Rik Westland, Michiel F. Schreuder, David F. van der Lof, Annemieke Vermeulen, Inge M. J. Dekker-van der Meer, Arend Bökenkamp, Joanna A. E. van Wijk

Published in: Pediatric Nephrology | Issue 11/2014

Abstract

Background

Children with a solitary functioning kidney are at increased risk of developing chronic kidney disease. Hypertension may be an early indicator of renal dysfunction in these patients. We determined blood pressure (BP) profiles of children with a solitary functioning kidney by using ambulatory BP monitoring (ABPM).

Methods

To assess the occurrence with (pre)hypertension, we compared ABPM to office BP measurement in 47 children with a solitary functioning kidney. None of the subjects used antihypertensive agents or had been hypertensive during previous clinical visits.

Results

Mean age of study subjects was 12.7 (±3.3) years. Hypertension was identified in ten (21 %) subjects with ABPM, whereas only two (4 %) children were hypertensive during office BP measurement (p < 0.01). Fifteen (32 %) children had an ABPM standard deviation (SD) value ≥90th percentile versus six (13 %) subjects based on office BP measurement (p = 0.051). Although 24-h ABPM SD scores were higher in the congenital type than in the acquired type of solitary functioning kidney (p ≤ 0.01), the proportions of subjects with 24-h ABPM hypertension were similar between groups (congenital 25 % versus acquired 16 %; p = NS).

Conclusions

Based on ABPM, one in five children with a solitary functioning kidney has hypertension. As the majority of these subjects were not hypertensive during office BP measurements, ABPM should be considered in the clinical management of solitary functioning kidney patients.

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Title: Ambulatory blood pressure monitoring is recommended in the clinical management of children with a solitary functioning kidney
Authors: Rik Westland
Michiel F. Schreuder
David F. van der Lof
Annemieke Vermeulen
Inge M. J. Dekker-van der Meer
Arend Bökenkamp
Joanna A. E. van Wijk
Publication date: 01-11-2014
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Nephrology / Issue 11/2014
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-014-2853-0

At a glance: The STEP trials

Springer Medicine

Ambulatory blood pressure monitoring is recommended in the clinical management of children with a solitary functioning kidney

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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