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Published in: Pediatric Nephrology 3/2012

01-03-2012 | Original Article

Microalbuminuria in children with primary and white-coat hypertension

Authors: Tomáš Seeman, Michael Pohl, Daniela Palyzova, Ulrike John

Published in: Pediatric Nephrology | Issue 3/2012

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Abstract

Microalbuminuria serves as an early marker of hypertension-related renal damage in adults. However, data on the prevalence of microalbuminuria in paediatric hypertensive patients in general and in children with white-coat hypertension (WCH) specifically are lacking. The aim of our study was to investigate the prevalence of microalbuminuria in children with primary hypertension (PH) and WCH, respectively. This was a retrospective case review of children with PH and WCH treated at three paediatric nephrology centres. Untreated children with either form of hypertension for whom measurements of urinary albumin excretion (UAE) had been performed were enrolled in the study. The study cohort comprised 52 children (39 boys) with hypertension (26 children with PH, 26 with WCH). Microalbuminuria (>3.2 mg/mmol creatinine) was present in 20% of children with PH and none of the children with WCH (p < 0.01). Children with PH had a higher median UAE than those with WCH (1.27 ± 1.92 vs. 0.66 ± 0.46 mg/mmol creatinine, p < 0.05). Based on these results, we suggest that children with PH have an increased prevalence of microalbuminuria, while children with WCH show no signs of hypertension-related renal damage.
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Metadata
Title
Microalbuminuria in children with primary and white-coat hypertension
Authors
Tomáš Seeman
Michael Pohl
Daniela Palyzova
Ulrike John
Publication date
01-03-2012
Publisher
Springer-Verlag
Published in
Pediatric Nephrology / Issue 3/2012
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-011-2019-2

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