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At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
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Pediatric Nephrology
Literature
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Schreiner MS (2003) Paediatric clinical trials: redressing the imbalance. Nat Rev Drug Discov 2:949–961PubMedCrossRef
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Pandolfini C, Bonati M (2005) A literature review on off-label drug use in children. Eur J Pediatr 164:552–558PubMedCrossRef
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Stanton A, Jensen C, Nussberger J, Obrien E (2003) Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren. Hypertension 42:1137–1143PubMedCrossRef
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Rakusan D, Kujal P, Kramer HJ, Husková Z, Vanourková Z, Vernerová Z, Mrázová I, Thumová M, Cervenka L, Vanecková I (2010) Persistent antihypertensive effect of aliskiren is accompanied by reduced proteinuria and normalization of glomerular area in Ren-2 transgenic rats. Am J Physiol Renal Physiol 299:F758–F766PubMedCrossRef
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Metadata
Title
Not ready for prime time: aliskiren for treatment of hypertension or proteinuria in children
Author
Joseph T. Flynn
Publication date
01-03-2011
Publisher
Springer-Verlag
Published in
Pediatric Nephrology / Issue 3/2011
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-010-1726-4

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