Skip to main content
Top
Published in: Pediatric Nephrology 1/2009

01-01-2009 | Original Article

Medical management of children with primary hypertension by pediatric subspecialists

Authors: Esther Y. Yoon, Matthew M. Davis, Albert Rocchini, David Kershaw, Gary L. Freed

Published in: Pediatric Nephrology | Issue 1/2009

Login to get access

Abstract

Our aim was to characterize medical management of children with primary hypertension (HTN) by pediatric subspecialists. We performed a medical-record review of children ≤18 years with primary HTN seen at pediatric cardiology or pediatric nephrology clinics at an academic center. Main outcomes were whether treatment decision was in agreement with national guidelines, whether an antihypertensive medication was prescribed, and medication choice. One hundred and eighty children had ≥1 visit to a pediatric cardiology or nephrology clinic. The majority (83%) of children were pharmacologically managed according to national guidelines. However, only 1/3 children with stage 2 HTN received appropriate antihypertensive therapy from either subspecialty. Only 26 children were prescribed an antihypertensive drug. Children evaluated by pediatric nephrologists were fourfold more likely to receive an antihypertensive than children seen by pediatric cardiologists (29% vs. 7%; p < 0.001). However, all antihypertensive prescriptions were prescribed according to guidelines by both subspecialties. Medical management of children with primary HTN by pediatric cardiologists and pediatric nephrologists is largely consistent with guidelines. However, initiation of appropriate antihypertensive drugs for children with highest severity of HTN is equally poor for both subspecialties. Future studies should explore the factors underlying physicians’ reluctance to initiate recommended chronic pharmacologic therapy in children and its associated outcomes.
Literature
1.
go back to reference McNiece KL, Poffenbarger TS, Turner JL, Franco KD, Sorof JM, Portman RJ (2007) Prevalence of hypertension and pre-hypertension among adolescents. J Pediatr 150(6):640–644PubMedCrossRef McNiece KL, Poffenbarger TS, Turner JL, Franco KD, Sorof JM, Portman RJ (2007) Prevalence of hypertension and pre-hypertension among adolescents. J Pediatr 150(6):640–644PubMedCrossRef
2.
go back to reference Ford ES, Mokdad AH, Ajani UA (2004) Trends in risk factors for cardiovascular disease among children and adolescents in the United States. Pediatrics 114(6):1534–1544PubMedCrossRef Ford ES, Mokdad AH, Ajani UA (2004) Trends in risk factors for cardiovascular disease among children and adolescents in the United States. Pediatrics 114(6):1534–1544PubMedCrossRef
3.
go back to reference Luepker RV, Jacobs DR, Prineas RJ, Sinaiko AR (1999) Secular trends of blood pressure and body size in a multi-ethnic adolescent population: 1986 to 1996. J Pediatr 134(6):668–674PubMedCrossRef Luepker RV, Jacobs DR, Prineas RJ, Sinaiko AR (1999) Secular trends of blood pressure and body size in a multi-ethnic adolescent population: 1986 to 1996. J Pediatr 134(6):668–674PubMedCrossRef
4.
go back to reference Hansen ML, Gunn PW, Kaelber DC (2007) Underdiagnosis of hypertension in children and adolescents. JAMA 298(8):874–879PubMedCrossRef Hansen ML, Gunn PW, Kaelber DC (2007) Underdiagnosis of hypertension in children and adolescents. JAMA 298(8):874–879PubMedCrossRef
5.
go back to reference Fixler DE, Laird WP, Fitzgerald V, Stead S, Adams R (1979) Hypertension screening in schools: results of the Dallas study. Pediatrics 63(1):32–36PubMed Fixler DE, Laird WP, Fitzgerald V, Stead S, Adams R (1979) Hypertension screening in schools: results of the Dallas study. Pediatrics 63(1):32–36PubMed
6.
go back to reference Silverberg DS, Nostrand CV, Juchli B, Smith ES, Dorsser EV (1975) Screening for hypertension in a high school population. Can Med Assoc J 113(2):103–108PubMedPubMedCentral Silverberg DS, Nostrand CV, Juchli B, Smith ES, Dorsser EV (1975) Screening for hypertension in a high school population. Can Med Assoc J 113(2):103–108PubMedPubMedCentral
7.
go back to reference Sinaiko AR, Gomez-Marin O, Prineas RJ (1989) Prevalence of “significant” hypertension in junior high school-aged children: the Children and Adolescent Blood Pressure Program. J Pediatr 114(4 Pt 1):664–669PubMedCrossRef Sinaiko AR, Gomez-Marin O, Prineas RJ (1989) Prevalence of “significant” hypertension in junior high school-aged children: the Children and Adolescent Blood Pressure Program. J Pediatr 114(4 Pt 1):664–669PubMedCrossRef
8.
go back to reference National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents (2004) The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 114(2 Suppl):555–576CrossRef National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents (2004) The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 114(2 Suppl):555–576CrossRef
9.
go back to reference Erickson S, Tolstykh I, Selby JV, Mendoza G, Iribarren C, Eisner MD (2005) The impact of allergy and pulmonary specialist care on emergency asthma utilization in a large managed care organization. Health Serv Res 40(5 Pt 1):1443–1465PubMedPubMedCentralCrossRef Erickson S, Tolstykh I, Selby JV, Mendoza G, Iribarren C, Eisner MD (2005) The impact of allergy and pulmonary specialist care on emergency asthma utilization in a large managed care organization. Health Serv Res 40(5 Pt 1):1443–1465PubMedPubMedCentralCrossRef
10.
go back to reference Moy JN, Grant EN, Turner-Roan K, Li T, Weiss KB (1999) Asthma care practices, perceptions, and beliefs of Chicago-area asthma specialists. Chicago Asthma Surveillance Initiative Project Team. Chest 116(4 Suppl 1):154S–162SPubMedCrossRef Moy JN, Grant EN, Turner-Roan K, Li T, Weiss KB (1999) Asthma care practices, perceptions, and beliefs of Chicago-area asthma specialists. Chicago Asthma Surveillance Initiative Project Team. Chest 116(4 Suppl 1):154S–162SPubMedCrossRef
11.
go back to reference Eisner MD, Katz PP, Yelin EH, Henke J, Smith S, Blanc PD (1998) Assessment of asthma severity in adults with asthma treated by family practitioners, allergists, and pulmonologists. Med Care 36(11):1567–1577PubMedCrossRef Eisner MD, Katz PP, Yelin EH, Henke J, Smith S, Blanc PD (1998) Assessment of asthma severity in adults with asthma treated by family practitioners, allergists, and pulmonologists. Med Care 36(11):1567–1577PubMedCrossRef
13.
go back to reference Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PA, Rubin HR (1999) Why don’t physicians follow clinical practice guidelines? A framework for improvement. JAMA 282(15):1458–1465PubMedCrossRef Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PA, Rubin HR (1999) Why don’t physicians follow clinical practice guidelines? A framework for improvement. JAMA 282(15):1458–1465PubMedCrossRef
14.
go back to reference Finkelstein JA, Lozano P, Shulruff R, Inui TS, Soumerai SB, Ng M, Weiss KB (2000) Self-reported physician practices for children with asthma: are national guidelines followed? Pediatrics 106(4 Suppl):886–896PubMed Finkelstein JA, Lozano P, Shulruff R, Inui TS, Soumerai SB, Ng M, Weiss KB (2000) Self-reported physician practices for children with asthma: are national guidelines followed? Pediatrics 106(4 Suppl):886–896PubMed
15.
go back to reference Cabana MD, Clark N (2003) Challenges in evaluating methods to improve physician practice. J Pediatr 143(4):413–414PubMedCrossRef Cabana MD, Clark N (2003) Challenges in evaluating methods to improve physician practice. J Pediatr 143(4):413–414PubMedCrossRef
16.
go back to reference Cabana MD, Ebel BE, Cooper-Patrick L, Powe NR, Rubin HR, Rand CS (2000) Barriers pediatricians face when using asthma practice guidelines. Arch Pediatr Adolesc Med 154(7):685–693PubMedCrossRef Cabana MD, Ebel BE, Cooper-Patrick L, Powe NR, Rubin HR, Rand CS (2000) Barriers pediatricians face when using asthma practice guidelines. Arch Pediatr Adolesc Med 154(7):685–693PubMedCrossRef
17.
go back to reference Cabana MD, Medzihradsky OF, Rubin HR, Freed GL (2001) Applying clinical guidelines to pediatric practice. Pediatr Ann 30(5):274–282PubMedCrossRef Cabana MD, Medzihradsky OF, Rubin HR, Freed GL (2001) Applying clinical guidelines to pediatric practice. Pediatr Ann 30(5):274–282PubMedCrossRef
18.
go back to reference Cabana MD, Rand CS, Becher OJ, Rubin HR (2001) Reasons for pediatrician nonadherence to asthma guidelines. Arch Pediatr Adolesc Med 55(9):1057–1062CrossRef Cabana MD, Rand CS, Becher OJ, Rubin HR (2001) Reasons for pediatrician nonadherence to asthma guidelines. Arch Pediatr Adolesc Med 55(9):1057–1062CrossRef
19.
go back to reference Riekert KA, Butz AM, Eggleston PA, Huss K, Winkelstein M, Rand CS (2003) Caregiver-physician medication concordance and undertreatment of asthma among inner-city children. Pediatrics 111(3):e214–220PubMedCrossRef Riekert KA, Butz AM, Eggleston PA, Huss K, Winkelstein M, Rand CS (2003) Caregiver-physician medication concordance and undertreatment of asthma among inner-city children. Pediatrics 111(3):e214–220PubMedCrossRef
20.
go back to reference Eggleston PA, Malveaux FJ, Butz AM, Huss K, Thompson L, Kolodner K, Rand CS (1998) Medications used by children with asthma living in the inner city. Pediatrics 101(3 Pt 1):349–354PubMedCrossRef Eggleston PA, Malveaux FJ, Butz AM, Huss K, Thompson L, Kolodner K, Rand CS (1998) Medications used by children with asthma living in the inner city. Pediatrics 101(3 Pt 1):349–354PubMedCrossRef
21.
go back to reference Halterman JS, Yoos HL, Kaczorowski JM, McConnochie K, Holzhauer RJ, Conn KM, Lauver S, Szilagyi PG (2002) Providers underestimate symptom severity among urban children with asthma. Arch Pediatr Adolesc Med 156(2):141–146PubMedCrossRef Halterman JS, Yoos HL, Kaczorowski JM, McConnochie K, Holzhauer RJ, Conn KM, Lauver S, Szilagyi PG (2002) Providers underestimate symptom severity among urban children with asthma. Arch Pediatr Adolesc Med 156(2):141–146PubMedCrossRef
22.
go back to reference Daniels SR, Greer FR (2008) Lipid screening and cardiovascular health in childhood. Pediatrics 122(1):198–208PubMedCrossRef Daniels SR, Greer FR (2008) Lipid screening and cardiovascular health in childhood. Pediatrics 122(1):198–208PubMedCrossRef
23.
go back to reference Woroniecki RP, Flynn JT (2005) How are hypertensive children evaluated and managed? A survey of North American pediatric nephrologists. Pediatr Nephrol 20(6):791–797PubMedCrossRef Woroniecki RP, Flynn JT (2005) How are hypertensive children evaluated and managed? A survey of North American pediatric nephrologists. Pediatr Nephrol 20(6):791–797PubMedCrossRef
24.
go back to reference The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002) Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 88(23):2981–2997CrossRef The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002) Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 88(23):2981–2997CrossRef
25.
go back to reference Mintzes B, Barer ML, Kravitz RL, Bassett K, Lexchin J, Kazanjian A, Evans RG, Pan R, Marion SA (2003) How does direct-to-consumer advertising (DTCA) affect prescribing? A survey in primary care environments with and without legal DTCA. CMAJ 169(5):405–412PubMedPubMedCentral Mintzes B, Barer ML, Kravitz RL, Bassett K, Lexchin J, Kazanjian A, Evans RG, Pan R, Marion SA (2003) How does direct-to-consumer advertising (DTCA) affect prescribing? A survey in primary care environments with and without legal DTCA. CMAJ 169(5):405–412PubMedPubMedCentral
26.
go back to reference Kravitz RL, Epstein RM, Feldman MD, Franz CE, Azari R, Wilkes MS, Hinton L, Franks P (2005) Influence of patients’ requests for direct-to-consumer advertised antidepressants: a randomized controlled trial. JAMA 293(16):1995–2002PubMedPubMedCentralCrossRef Kravitz RL, Epstein RM, Feldman MD, Franz CE, Azari R, Wilkes MS, Hinton L, Franks P (2005) Influence of patients’ requests for direct-to-consumer advertised antidepressants: a randomized controlled trial. JAMA 293(16):1995–2002PubMedPubMedCentralCrossRef
27.
go back to reference Kravitz RL, Bell RA, Azari R, Kelly-Reif S, Krupat E, Thom DH (2003) Direct observation of requests for clinical services in office practice: what do patients want and do they get it? Arch Intern Med 163(14):1673–1681PubMedCrossRef Kravitz RL, Bell RA, Azari R, Kelly-Reif S, Krupat E, Thom DH (2003) Direct observation of requests for clinical services in office practice: what do patients want and do they get it? Arch Intern Med 163(14):1673–1681PubMedCrossRef
28.
go back to reference Spence MM, Teleki SS, Cheetham TC, Schweitzer SO, Millares M (2005) Direct-to-consumer advertising of COX-2 inhibitors: effect on appropriateness of prescribing. Med Care Res Rev 62(5):544–559PubMedCrossRef Spence MM, Teleki SS, Cheetham TC, Schweitzer SO, Millares M (2005) Direct-to-consumer advertising of COX-2 inhibitors: effect on appropriateness of prescribing. Med Care Res Rev 62(5):544–559PubMedCrossRef
29.
go back to reference Mangione-Smith R, McGlynn EA, Elliott MN, Krogstad P, Brook RH (1999) The relationship between perceived parental expectations and pediatrician antimicrobial prescribing behavior. Pediatrics 103(4 Pt 1):711–718PubMedCrossRef Mangione-Smith R, McGlynn EA, Elliott MN, Krogstad P, Brook RH (1999) The relationship between perceived parental expectations and pediatrician antimicrobial prescribing behavior. Pediatrics 103(4 Pt 1):711–718PubMedCrossRef
30.
go back to reference Karras DJ, Ong S, Moran GJ, Nakase J, Kuehnert MJ, Jarvis WR, Talan DA, EMERGEncy ID NET Study Group (2003) Antibiotic use for emergency department patients with acute diarrhea: Prescribing practices, patient expectations, and patient satisfaction. Ann Emerg Med 42(6):835–842PubMedCrossRef Karras DJ, Ong S, Moran GJ, Nakase J, Kuehnert MJ, Jarvis WR, Talan DA, EMERGEncy ID NET Study Group (2003) Antibiotic use for emergency department patients with acute diarrhea: Prescribing practices, patient expectations, and patient satisfaction. Ann Emerg Med 42(6):835–842PubMedCrossRef
Metadata
Title
Medical management of children with primary hypertension by pediatric subspecialists
Authors
Esther Y. Yoon
Matthew M. Davis
Albert Rocchini
David Kershaw
Gary L. Freed
Publication date
01-01-2009
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Nephrology / Issue 1/2009
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-008-0970-3

Other articles of this Issue 1/2009

Pediatric Nephrology 1/2009 Go to the issue