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Pediatric Nephrology
Published in: Pediatric Nephrology 1/2009

01-01-2009 | Original Article

Unilateral multicystic dysplastic kidney: single-center experience

Authors: Aysel Kiyak, Alev Yilmaz, Pinar Turhan, Serdar Sander, Gulay Aydin, Gonul Aydogan

Published in: Pediatric Nephrology | Issue 1/2009

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Abstract

Multicystic dysplastic kidney (MCDK) is one of the most common renal abnormalities in children. The aim of our study was to evaluate the clinical course and outcome of patients with MCDK. Ninety pediatric patients with unilateral MCDK followed by the Pediatric Nephrology Department of Bakırkoy Maternity and Children’s Hospital between 1990 and 2007 were included in this retrospective study. The dimercaptosuccinic acid radionuclide scan revealed no function in MCDK in all of our patients. Voiding cystourethrogram was performed in all patients. Twenty patients (22.2%) had abnormalities in the contralateral kidney. Nephrectomy was performed in 41 patients (45.5%). Twelve patients had undergone routine nephrectomy before 1996. Since then, patients have been followed up conservatively, and nephrectomy has been performed only when indicated. Indication of nephrectomy was arterial hypertension in 16 patients (23.1%), recurrent urinary tract infection (UTI) in 11 (15.9%), and severe abdominal pain in two (2.8%). Hypertension was noted within the first year of life in all patients except two. MCDK completely involuted in 39.3% within 48 months. There was no malignant transformation, proteinuria, or renal failure. In conclusion, hypertension is often noticed in infants with MCDK. Uninephrectomy leads to normalization. However, prospective studies are needed to exclude a spontaneous improvement of hypertension.
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Metadata
Title
Unilateral multicystic dysplastic kidney: single-center experience
Authors
Aysel Kiyak
Alev Yilmaz
Pinar Turhan
Serdar Sander
Gulay Aydin
Gonul Aydogan
Publication date
01-01-2009
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Nephrology / Issue 1/2009
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-008-0942-7

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