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01-11-2004 | Review

Pathomechanisms and the diagnosis of arterial hypertension in pediatric renal allograft recipients

Authors: Rainer Büscher, Udo Vester, A.-M. Wingen, Peter F. Hoyer

Published in: Pediatric Nephrology | Issue 11/2004

Abstract

Arterial hypertension is common in pediatric renal allograft recipients. While the causes are multifactorial, including chronic graft rejection, immunosuppressive therapy, and renal vascular disorders, the effect of hypertension on renal allograft function is detrimental. As in adults, if not treated early and aggressively, hypertension may lead to cardiovascular damage and graft failure. Pathophysiological changes in the arteries and kidney after renal transplantation and the impact of receptor regulation have not been studied extensively in children. For identifying children with hypertension following renal transplantation casual blood pressure measurements do not accurately reflect average arterial blood pressure and circadian blood pressure rhythm. Ambulatory 24-h blood pressure monitoring should regularly be applied in transplant patients. The purpose of this review is to analyze pathophysiological aspects of risk factors for arterial hypertension and underline the importance of regular blood pressure monitoring and early therapeutic intervention.

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Title: Pathomechanisms and the diagnosis of arterial hypertension in pediatric renal allograft recipients
Authors: Rainer Büscher
Udo Vester
A.-M. Wingen
Peter F. Hoyer
Publication date: 01-11-2004
Publisher: Springer-Verlag
Published in: Pediatric Nephrology / Issue 11/2004
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-004-1601-2

At a glance: The STEP trials

Springer Medicine

Pathomechanisms and the diagnosis of arterial hypertension in pediatric renal allograft recipients

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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