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Published in: Surgical Endoscopy 6/2020

01-06-2020 | Cholecystectomy

Laparoendoscopic rendezvous versus ERCP followed by laparoscopic cholecystectomy for the management of cholecysto-choledocholithiasis: a retrospectively cohort study

Authors: Yawei Qian, Jianglin Xie, Ping Jiang, Yuchun Yin, Quan Sun

Published in: Surgical Endoscopy | Issue 6/2020

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Abstract

Background

There are a variety of strategies for the treatment of patients with cholecysto-choledocholithiasis (CCL). Although the surgical approach of choice is preoperative ERCP and laparoscopic cholecystectomy (ERCP + LC), controversy remains regarding which procedure is optimal for CCL.

Methods

To evaluate the safety and effectiveness of laparoendoscopic rendezvous (LERV) versus ERCP + LC for CCL, a total of 528 patients with CCL were retrospectively studied from January 2013 to December 2018. The patients were scheduled to undergo either the LERV or ERCP + LC procedure. The LERV group included 123 cases, whereas the ERCP + LC group contained 137 cases. The incidence of postoperative complications, success of stone clearance, length of hospital stay, and hospitalization charges were statistically analyzed.

Results

The incidence of pancreatitis was lower in the LERV group than in the ERCP + LC group (3/123 vs. 12/137, P = 0.0291). The median level of post-ERCP amylase was much lower in the LERV group (202.5 U/dL vs. 328.1 U/dL, P < 0.01). However, there was no significant difference in the stone clearance rate or other early complications between the two groups. Further study showed that the length of hospital stay and cost in the LERV group were less than those in the ERCP + LC group (12 days vs. 18 days, P < 0.01; 53591.4¥ vs. 60089.2¥, P < 0.01). In addition, more patients in the two-stage procedure group experienced later biliary complications compared with those in the one-stage approach group (34/137 vs. 4/123, P < 0.05). However, the median operation time was 107.7 min in the two-stage group and 139.8 min in the one-stage group (P < 0.05).

Conclusions

The LERV technique is a safe and effective approach for CCL with lower pancreatitis; it was associated with few later biliary complications, shortened hospital stays, and fewer charges but significantly longer operative time.
Literature
1.
go back to reference Dasari BV, Tan CJ, Gurusamy KS, Bobby VMD, Chuan JT, Kurinchi SG, David JM, Gareth K, Lloyd MK, Tom D, Mark AT (2013) Surgical versus endoscopic treatment of bile duct stones. Cochrane Database Syst Rev 8:CD003327 Dasari BV, Tan CJ, Gurusamy KS, Bobby VMD, Chuan JT, Kurinchi SG, David JM, Gareth K, Lloyd MK, Tom D, Mark AT (2013) Surgical versus endoscopic treatment of bile duct stones. Cochrane Database Syst Rev 8:CD003327
2.
go back to reference Prasson P, Bai X, Zhang Q, Liang T (2016) One-stage laproendoscopic procedure versus two-stage procedure in the management for gallstone disease and biliary duct calculi: a systemic review and meta-analysis. Surg Endosc 30:3582–3590CrossRef Prasson P, Bai X, Zhang Q, Liang T (2016) One-stage laproendoscopic procedure versus two-stage procedure in the management for gallstone disease and biliary duct calculi: a systemic review and meta-analysis. Surg Endosc 30:3582–3590CrossRef
3.
go back to reference European Association for the Study of the Liver (EASL) (2016) EASL clinical practice guidelines on the prevention, diagnosis and treatment of gallstones. J Hepatol 65:146–181CrossRef European Association for the Study of the Liver (EASL) (2016) EASL clinical practice guidelines on the prevention, diagnosis and treatment of gallstones. J Hepatol 65:146–181CrossRef
4.
go back to reference Mine T, Morizane T, Kawaguchi Y, Akashi R, Hanada K, Ito T, Kanno A, Kida M, Miyagawa H, Yamaguchi T, Mayumi T, Takeyama Y, Shimosegawa T (2017) Clinical practice guideline for post-ERCP pancreatitis. J Gastroenterol 52:1013–1022CrossRef Mine T, Morizane T, Kawaguchi Y, Akashi R, Hanada K, Ito T, Kanno A, Kida M, Miyagawa H, Yamaguchi T, Mayumi T, Takeyama Y, Shimosegawa T (2017) Clinical practice guideline for post-ERCP pancreatitis. J Gastroenterol 52:1013–1022CrossRef
5.
go back to reference Nalankilli K, Kannuthurai S, Moss A (2016) A modern approach to ERCP: maintaining efficacy while optimising safety. Dig Endosc 28(Suppl 1):70–76CrossRef Nalankilli K, Kannuthurai S, Moss A (2016) A modern approach to ERCP: maintaining efficacy while optimising safety. Dig Endosc 28(Suppl 1):70–76CrossRef
6.
go back to reference Enochsson L, Lindberg B, Swahn F, Arnelo U (2004) Intraoperative endoscopic retrograde cholangiopancreatography (ERCP) to remove common bile duct stones during routine laparoscopic cholecystectomy does not prolong hospitalization: a 2-year experience. Surg Endosc 18:367–371CrossRef Enochsson L, Lindberg B, Swahn F, Arnelo U (2004) Intraoperative endoscopic retrograde cholangiopancreatography (ERCP) to remove common bile duct stones during routine laparoscopic cholecystectomy does not prolong hospitalization: a 2-year experience. Surg Endosc 18:367–371CrossRef
7.
go back to reference Feretis C, Kalliakmanis B, Benakis P, Apostolids N (1994) Laparoscopic transcystic papillotomy under endoscopic control for bile duct stones. Endoscopy 26:697–700CrossRef Feretis C, Kalliakmanis B, Benakis P, Apostolids N (1994) Laparoscopic transcystic papillotomy under endoscopic control for bile duct stones. Endoscopy 26:697–700CrossRef
8.
go back to reference Rábago LR, Vicente C, Soler F, Delgado M, Moral I, Guerra I, Castro JL, Quintanilla E, Romeo J, Llorente R, Vázquez Echarri J, Martínez-Veiga JL, Gea F (2006) Two-stage treatment with preoperative endoscopic retrograde cholangiopancreatography (ERCP) compared with single-stage treatment with intraoperative ERCP for patients with symptomatic cholelithiasis with possible choledocholithiasis. Endoscopy 38:779–786CrossRef Rábago LR, Vicente C, Soler F, Delgado M, Moral I, Guerra I, Castro JL, Quintanilla E, Romeo J, Llorente R, Vázquez Echarri J, Martínez-Veiga JL, Gea F (2006) Two-stage treatment with preoperative endoscopic retrograde cholangiopancreatography (ERCP) compared with single-stage treatment with intraoperative ERCP for patients with symptomatic cholelithiasis with possible choledocholithiasis. Endoscopy 38:779–786CrossRef
9.
go back to reference Liverani A, Muroni M, Santi F, Neri T, Anastasio G, Moretti M, Favi F, Solinas L (2013) One-step laparoscopic and endoscopic treatment of gallbladder and common bile duct stones: our experience of the last 9 years in a retrospective study. Am Surg 79:1243–1247PubMed Liverani A, Muroni M, Santi F, Neri T, Anastasio G, Moretti M, Favi F, Solinas L (2013) One-step laparoscopic and endoscopic treatment of gallbladder and common bile duct stones: our experience of the last 9 years in a retrospective study. Am Surg 79:1243–1247PubMed
10.
go back to reference Ricci C, Pagano N, Taffurelli G, Pacilio CA, Migliori M, Bazzoli F, Casadei R, Minni F (2018) Comparison of efficacy and safety of 4 combinations of laparoscopic and intraoperative techniques for management of gallstone disease with biliary duct calculi: a systematic review and network meta-analysis. JAMA Surg 1539:e181167CrossRef Ricci C, Pagano N, Taffurelli G, Pacilio CA, Migliori M, Bazzoli F, Casadei R, Minni F (2018) Comparison of efficacy and safety of 4 combinations of laparoscopic and intraoperative techniques for management of gallstone disease with biliary duct calculi: a systematic review and network meta-analysis. JAMA Surg 1539:e181167CrossRef
11.
go back to reference Vettoretto N, Arezzo A, Famiglietti F, Cirocchi R, Moja L, Morino M (2018) Laparoscopic-endoscopic rendezvous versus preoperative endoscopic sphincterotomy in people undergoing laparoscopic cholecystectomy for stones in the gallbladder and bile duct. Cochrane Database Syst Rev 4:CD010507PubMed Vettoretto N, Arezzo A, Famiglietti F, Cirocchi R, Moja L, Morino M (2018) Laparoscopic-endoscopic rendezvous versus preoperative endoscopic sphincterotomy in people undergoing laparoscopic cholecystectomy for stones in the gallbladder and bile duct. Cochrane Database Syst Rev 4:CD010507PubMed
12.
go back to reference La BG, Gardini A, Cavargini E, Casadei A, Morgagni P, Bazzocchi F, D’Acapito F, Cavaliere D, Curti R, Tringali D, Cucchetti A, Ercolani G (2018) Laparoendoscopic rendezvous in the treatment of cholecysto-choledocholitiasis: a single series of 200 patients. Surg Endosc 32:3868–3873CrossRef La BG, Gardini A, Cavargini E, Casadei A, Morgagni P, Bazzocchi F, D’Acapito F, Cavaliere D, Curti R, Tringali D, Cucchetti A, Ercolani G (2018) Laparoendoscopic rendezvous in the treatment of cholecysto-choledocholitiasis: a single series of 200 patients. Surg Endosc 32:3868–3873CrossRef
13.
go back to reference Staritz M, Ewe K, Meyer BKH (1982) Endoscopic papillary dilatation, a possible alternative to endoscopic papillotomy. Lancet 1:1306–1307CrossRef Staritz M, Ewe K, Meyer BKH (1982) Endoscopic papillary dilatation, a possible alternative to endoscopic papillotomy. Lancet 1:1306–1307CrossRef
14.
go back to reference Ding J, Li F, Zhu HY, Zhang XW (2015) Endoscopic treatment of difficult extrahepatic bile duct stones, EPBD or EST: an anatomic view. World J Gastrointest Endosc 7:274–277CrossRef Ding J, Li F, Zhu HY, Zhang XW (2015) Endoscopic treatment of difficult extrahepatic bile duct stones, EPBD or EST: an anatomic view. World J Gastrointest Endosc 7:274–277CrossRef
15.
go back to reference Miscusi G, Gasparrini M, Petruzziello L, Taglienti D, Onorato M, Otti M, Montori J (1997) Endolaparoscopic ‘‘Rendez-vous’’ in the treatment of cholecystocholedochal calculosis. G Chir 18:655–657PubMed Miscusi G, Gasparrini M, Petruzziello L, Taglienti D, Onorato M, Otti M, Montori J (1997) Endolaparoscopic ‘‘Rendez-vous’’ in the treatment of cholecystocholedochal calculosis. G Chir 18:655–657PubMed
16.
go back to reference Tzovaras G, Baloyiannis I, Zachari E, Symeonidis D, Zacharoulis D, Kapsoritakis A, Paroutoglou G, Potamianos S (2012) Laparoendoscopic rendezvous versus preoperative ERCP and laparoscopic cholecystectomy for the management of cholecysto-choledocholithiasis: interim analysis of a controlled randomized trial. Ann Surg 255:435–439CrossRef Tzovaras G, Baloyiannis I, Zachari E, Symeonidis D, Zacharoulis D, Kapsoritakis A, Paroutoglou G, Potamianos S (2012) Laparoendoscopic rendezvous versus preoperative ERCP and laparoscopic cholecystectomy for the management of cholecysto-choledocholithiasis: interim analysis of a controlled randomized trial. Ann Surg 255:435–439CrossRef
17.
go back to reference Gaetano LG, Francesco B, Maria S, Saverio L (2010) Simultaneous laparoendoscopic rendezvous for the treatment of cholecystocholedocholithiasis. Surg Endosc 24:769–780CrossRef Gaetano LG, Francesco B, Maria S, Saverio L (2010) Simultaneous laparoendoscopic rendezvous for the treatment of cholecystocholedocholithiasis. Surg Endosc 24:769–780CrossRef
18.
go back to reference Feng Q, Huang Y, Wang K, Yuan R, Xiong X, Wu L (2016) Laparoscopic transcystic common bile duct exploration: advantages over laparoscopic choledochotomy. PLoS ONE 11:e0162885CrossRef Feng Q, Huang Y, Wang K, Yuan R, Xiong X, Wu L (2016) Laparoscopic transcystic common bile duct exploration: advantages over laparoscopic choledochotomy. PLoS ONE 11:e0162885CrossRef
19.
go back to reference Gupta N (2016) Role of laparoscopic common bile duct exploration in the management of choledocholithiasis. World J Gastrointest Surg 8:376–381CrossRef Gupta N (2016) Role of laparoscopic common bile duct exploration in the management of choledocholithiasis. World J Gastrointest Surg 8:376–381CrossRef
20.
go back to reference Lu J, Cheng Y, Xiong XZ, Lin YX, Wu SJ, Cheng NS (2012) Two-stage vs single-stage management for concomitant gallstones and common bile duct stones. World J Gastroenterol 18:3156–3166CrossRef Lu J, Cheng Y, Xiong XZ, Lin YX, Wu SJ, Cheng NS (2012) Two-stage vs single-stage management for concomitant gallstones and common bile duct stones. World J Gastroenterol 18:3156–3166CrossRef
21.
go back to reference Martin DJ, Vernon DR, Toouli J (2006) Surgical versus endoscopic treatment of bile duct stones. Cochrane Database Syst Rev 2:CD003327 Martin DJ, Vernon DR, Toouli J (2006) Surgical versus endoscopic treatment of bile duct stones. Cochrane Database Syst Rev 2:CD003327
22.
go back to reference El-Geidie AA (2011) Laparoendoscopic management of concomitant gallbladder stones and common bile duct stones: what is the best technique? Surg Laparosc Endosc Percutan Tech 21:282–287CrossRef El-Geidie AA (2011) Laparoendoscopic management of concomitant gallbladder stones and common bile duct stones: what is the best technique? Surg Laparosc Endosc Percutan Tech 21:282–287CrossRef
23.
go back to reference Cavina E, Franceschi M, Sidoti F, Goletti O, Buccianti P, Chiarugi M (1998) Laparo-endoscopic “rendezvous”: a new technique in the choledocholithiasis treatment. Hepatogastroenterology 45:1430–1435PubMed Cavina E, Franceschi M, Sidoti F, Goletti O, Buccianti P, Chiarugi M (1998) Laparo-endoscopic “rendezvous”: a new technique in the choledocholithiasis treatment. Hepatogastroenterology 45:1430–1435PubMed
24.
go back to reference Basso N, Pizzuto G, Surgo D, Materia A, Silecchia G, Fantini A, Fiocca F, Trentino P (1999) Laparoscopic cholecystectomy and intraoperative endoscopic sphincterotomy in the treatment of cholecysto-choledocholithiasis. Gastrointest Endosc 50:532–535CrossRef Basso N, Pizzuto G, Surgo D, Materia A, Silecchia G, Fantini A, Fiocca F, Trentino P (1999) Laparoscopic cholecystectomy and intraoperative endoscopic sphincterotomy in the treatment of cholecysto-choledocholithiasis. Gastrointest Endosc 50:532–535CrossRef
25.
go back to reference Pezzilli R, Romboli E, Campana D, Corinaldesi R (2002) Mechanisms involved in the onset of post-ERCP pancreatitis. JOP 3:162–168PubMed Pezzilli R, Romboli E, Campana D, Corinaldesi R (2002) Mechanisms involved in the onset of post-ERCP pancreatitis. JOP 3:162–168PubMed
26.
go back to reference Testoni PA (2002) Why the incidence of post-ERCP pancreatitis varies considerably? Factors affecting the diagnosis and the incidence of this complication. JOP 3:195–201PubMed Testoni PA (2002) Why the incidence of post-ERCP pancreatitis varies considerably? Factors affecting the diagnosis and the incidence of this complication. JOP 3:195–201PubMed
27.
go back to reference Testoni PA, Mariani A, Giussani A, Vailati C, Masci E, Macarri G, Ghezzo L, Familiari L, Giardullo N, Mutignani M, Lombardi G, Talamini G, Spadaccini A, Briglia R, Piazzi L; SEIFRED Group (2010) Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study. Am J Gastroenterol 105:1753–1761CrossRef Testoni PA, Mariani A, Giussani A, Vailati C, Masci E, Macarri G, Ghezzo L, Familiari L, Giardullo N, Mutignani M, Lombardi G, Talamini G, Spadaccini A, Briglia R, Piazzi L; SEIFRED Group (2010) Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study. Am J Gastroenterol 105:1753–1761CrossRef
28.
go back to reference Sugiyama M, Atomi Y (2002) Risk factors predictive of late complications after endoscopic sphincterotomy for bile duct stones: long-term (more than 10 years) follow-up study. Am J Gastroenterol 97:2763–2767CrossRef Sugiyama M, Atomi Y (2002) Risk factors predictive of late complications after endoscopic sphincterotomy for bile duct stones: long-term (more than 10 years) follow-up study. Am J Gastroenterol 97:2763–2767CrossRef
29.
go back to reference Bostanci EB, Ercan M, Ozer I, Teke Z, Parlak E, Akoglu M (2010) Timing of elective laparoscopic cholecystectomy after endoscopic retrograde cholangiopancreaticography with sphincterotomy: a prospective observational study of 308 patients. Langenbecks Arch Surg 395:661–666CrossRef Bostanci EB, Ercan M, Ozer I, Teke Z, Parlak E, Akoglu M (2010) Timing of elective laparoscopic cholecystectomy after endoscopic retrograde cholangiopancreaticography with sphincterotomy: a prospective observational study of 308 patients. Langenbecks Arch Surg 395:661–666CrossRef
30.
go back to reference Salman B, Yilmaz U, Kerem M, Bedirli A, Sare M, Sakrak O, Tatlicioglu E (2009) The timing of laparoscopic cholecystectomy after endoscopic retrograde cholangiopancreaticography in cholelithiasis coexisting with choledocholithiasis. J Hepatobiliary Pancreat Surg 16:832–836CrossRef Salman B, Yilmaz U, Kerem M, Bedirli A, Sare M, Sakrak O, Tatlicioglu E (2009) The timing of laparoscopic cholecystectomy after endoscopic retrograde cholangiopancreaticography in cholelithiasis coexisting with choledocholithiasis. J Hepatobiliary Pancreat Surg 16:832–836CrossRef
31.
go back to reference Bove A, Di Renzo RM, Palone G, Testa D, Malerba V, Bongarzoni G (2018) Single-stage procedure for the treatment of cholecysto-choledocolithiasis: a surgical procedures review. Ther Clin Risk Manag 14:305–312CrossRef Bove A, Di Renzo RM, Palone G, Testa D, Malerba V, Bongarzoni G (2018) Single-stage procedure for the treatment of cholecysto-choledocolithiasis: a surgical procedures review. Ther Clin Risk Manag 14:305–312CrossRef
32.
go back to reference ElGeidie AA (2014) Single-session minimally invasive management of common bile duct stones. World J Gastroenterol 20:15144–15152CrossRef ElGeidie AA (2014) Single-session minimally invasive management of common bile duct stones. World J Gastroenterol 20:15144–15152CrossRef
33.
go back to reference Odabasi M, Yildiz MK, Abuoglu HH, Eris C, Ozkan E, Gunay E, Aktekin A, Muftuoglu MT (2013) A modified Rendezvous ERCP technique in duodenal diverticulum. World J Gastrointest Endosc 5:568–573CrossRef Odabasi M, Yildiz MK, Abuoglu HH, Eris C, Ozkan E, Gunay E, Aktekin A, Muftuoglu MT (2013) A modified Rendezvous ERCP technique in duodenal diverticulum. World J Gastrointest Endosc 5:568–573CrossRef
34.
go back to reference Garbarini A, Reggio D, Arolfo S, Bruno M, Passera R, Catalano G, Barletti C, Salizzoni M, Morino M, Petruzzelli L, Arezzo A (2017) Cost analysis of laparoendoscopic rendezvous versus preoperative ERCP and laparoscopic cholecystectomy in the management of cholecystocholedocholithiasis. Surg Endosc 31:3291–3296CrossRef Garbarini A, Reggio D, Arolfo S, Bruno M, Passera R, Catalano G, Barletti C, Salizzoni M, Morino M, Petruzzelli L, Arezzo A (2017) Cost analysis of laparoendoscopic rendezvous versus preoperative ERCP and laparoscopic cholecystectomy in the management of cholecystocholedocholithiasis. Surg Endosc 31:3291–3296CrossRef
35.
go back to reference La GG, Pesce A, Vitale M, Mannino M, Di MF, Di BM, Lombardo R, Puleo S, Russello D, Latteri S (2017) Efficacy of the laparoendoscopic “rendezvous” to treat cholecystocholedocholithiasis in 210 consecutive patients: a single center experience. Surg Laparosc Endosc Percutan Tech 27:e48–e52CrossRef La GG, Pesce A, Vitale M, Mannino M, Di MF, Di BM, Lombardo R, Puleo S, Russello D, Latteri S (2017) Efficacy of the laparoendoscopic “rendezvous” to treat cholecystocholedocholithiasis in 210 consecutive patients: a single center experience. Surg Laparosc Endosc Percutan Tech 27:e48–e52CrossRef
36.
go back to reference Erickson RA, Carlson B (1995) The role of endoscopic retrograde cholangiopancreatography in patients with laparoscopic cholecystectomies. Gastroenterology 109:252–263CrossRef Erickson RA, Carlson B (1995) The role of endoscopic retrograde cholangiopancreatography in patients with laparoscopic cholecystectomies. Gastroenterology 109:252–263CrossRef
37.
go back to reference Rogers SJ, Cello JP, Horn JK, Siperstein AE, Schecter WP, Campbell AR, Mackersie RC, Rodas A, Kreuwel HT, Harris HW (2010) Prospective randomized trial of LC + LCBDE vs ERCP/S + LC for common bile duct stone disease. Arch Surg 145:28–33PubMed Rogers SJ, Cello JP, Horn JK, Siperstein AE, Schecter WP, Campbell AR, Mackersie RC, Rodas A, Kreuwel HT, Harris HW (2010) Prospective randomized trial of LC + LCBDE vs ERCP/S + LC for common bile duct stone disease. Arch Surg 145:28–33PubMed
38.
go back to reference Lella F, Bagnolo F, Rebuffat C, Scalambra M, Bonassi U, Colombo E (2006) Use of the laparoscopic-endoscopic approach, the so-called “rendezvous” technique, in cholecystocholedocholithiasis: a valid method in cases with patient-related risk factors for post-ERCP pancreatitis. Surg Endosc 20:419–423CrossRef Lella F, Bagnolo F, Rebuffat C, Scalambra M, Bonassi U, Colombo E (2006) Use of the laparoscopic-endoscopic approach, the so-called “rendezvous” technique, in cholecystocholedocholithiasis: a valid method in cases with patient-related risk factors for post-ERCP pancreatitis. Surg Endosc 20:419–423CrossRef
39.
go back to reference Gagner M (2010) Intra-operative sphincterotomy and ERCP for choledocholithiasis during laparoscopic cholecystectomy. Surgery 147:463CrossRef Gagner M (2010) Intra-operative sphincterotomy and ERCP for choledocholithiasis during laparoscopic cholecystectomy. Surgery 147:463CrossRef
40.
go back to reference Mario M, Filippo B, Claudio M, Niccolò F, Riccardo R, Aldo G (2006) Preoperative endoscopic sphincterotomy versus laparoendoscopic rendezvous in patients with gallbladder and bile duct stones. Ann Surg 244:889–893CrossRef Mario M, Filippo B, Claudio M, Niccolò F, Riccardo R, Aldo G (2006) Preoperative endoscopic sphincterotomy versus laparoendoscopic rendezvous in patients with gallbladder and bile duct stones. Ann Surg 244:889–893CrossRef
Metadata
Title
Laparoendoscopic rendezvous versus ERCP followed by laparoscopic cholecystectomy for the management of cholecysto-choledocholithiasis: a retrospectively cohort study
Authors
Yawei Qian
Jianglin Xie
Ping Jiang
Yuchun Yin
Quan Sun
Publication date
01-06-2020
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 6/2020
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-019-07051-y

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