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Published in: Surgical Endoscopy 2/2019

01-02-2019 | Dynamic Manuscript

Laparoscopic duodenum-preserving total pancreatic head resection: a novel surgical approach for benign or low-grade malignant tumors

Authors: Jun Cao, Guo-lin Li, Jin-xing Wei, Wei-Bang Yang, Chang-zhen Shang, Ya-jin Chen, Wan Yee Lau, Jun Min

Published in: Surgical Endoscopy | Issue 2/2019

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Abstract

Background

Duodenum-preserving total pancreatic head resection (DPPHRt) is an accepted alternative surgical procedure for benign or low-grade malignant tumors of the pancreatic head by preserving the duodenum with its intact blood supply from the pancreatic duodenal arterial arcade. This study describes our experience in laparoscopic DPPHRt (LDPPHRt). To our knowledge, this is the first description of this novel minimally invasive operation.

Methods

From August 2016 to May 2017, all consecutive patients who underwent LDPPHRt for pancreatic head lesions at the HPB Surgery Department, Sun Yat-Sen Memorial Hospital in Guangzhou, China were enrolled into this retrospective study.

Results

There were ten women and two men. The average age was 37.3 years (range 8–61 years). The average diameter of the pancreatic head lesions on pre-operative CT/MR was 3.7 cm (range 2–4.8 cm). All the LDPPHRt procedures were performed successfully. There was no peri-operative death. The average operative time was 272.5 min (range 210–320 min). The average blood loss was 215 ml (range 50–450 ml). Post-operative complications included pancreatic fistula grade B (two patients, or 16.7%) and biliary fistula (two patients, or 16.7%). All the complications responded well to conservative treatment. The mean post-operative hospital stay was 11.5 days (range 6–25 days).

Conclusions

LDPPHRt provided a minimally invasive approach with good organ-preservation for benign or low-grade malignant tumors of the pancreatic head. The long-term oncological outcomes, and the exocrine and endocrine pancreatic functions after this operation require further studies.
Literature
1.
go back to reference Beger HG, Büchler M, Bittner RR et al (1989) Duodenum-preserving resection of the head of the pancreas in severe chronic pancreatitis. Early and late results. Ann Surg 209(3):273–278CrossRefPubMedPubMedCentral Beger HG, Büchler M, Bittner RR et al (1989) Duodenum-preserving resection of the head of the pancreas in severe chronic pancreatitis. Early and late results. Ann Surg 209(3):273–278CrossRefPubMedPubMedCentral
2.
go back to reference Diener MK, Rahbari NN, Fischer L et al (2008) Duodenum-preserving pancreatic head resection versus pancreatoduodenectomy for surgical treatment of chronic pancreatitis: a systematic review and meta-analysis. Ann Surg 247(6):950–961CrossRef Diener MK, Rahbari NN, Fischer L et al (2008) Duodenum-preserving pancreatic head resection versus pancreatoduodenectomy for surgical treatment of chronic pancreatitis: a systematic review and meta-analysis. Ann Surg 247(6):950–961CrossRef
3.
go back to reference Takada T, Yasuda H, Uchiyama K et al (1993) Duodenum-preserving pancreatoduodenostomy. A new technique for complete excision of the head of the pancreas with preservation of biliary and alimentary integrity. Hepatogastroenterology 40(4):356–359PubMed Takada T, Yasuda H, Uchiyama K et al (1993) Duodenum-preserving pancreatoduodenostomy. A new technique for complete excision of the head of the pancreas with preservation of biliary and alimentary integrity. Hepatogastroenterology 40(4):356–359PubMed
4.
go back to reference Takada T, Yasuda H, Uchiyama K, Hasegawa H (1995) Completeduodenum-preserving resection of the head of the pancreaswith preservation of the biliary tract. J Hepatobiliary Pancreat Surg 2:32–37CrossRef Takada T, Yasuda H, Uchiyama K, Hasegawa H (1995) Completeduodenum-preserving resection of the head of the pancreaswith preservation of the biliary tract. J Hepatobiliary Pancreat Surg 2:32–37CrossRef
5.
go back to reference Beger HG, Schwarz M, Poch B (2012) Duodenum-preserving total pancreatic head resection for benign cystic neoplastic lesions. J Gastrointest Surg 16(11):2160–2166CrossRefPubMed Beger HG, Schwarz M, Poch B (2012) Duodenum-preserving total pancreatic head resection for benign cystic neoplastic lesions. J Gastrointest Surg 16(11):2160–2166CrossRefPubMed
6.
go back to reference Beger HG, Siech M, Poch B (2013) Duodenum-preserving total pancreatic headresection: an organ-sparing operation technique for cystic neoplasms andnon-invasive malignant tumors. Chirurg 84:412–420CrossRefPubMed Beger HG, Siech M, Poch B (2013) Duodenum-preserving total pancreatic headresection: an organ-sparing operation technique for cystic neoplasms andnon-invasive malignant tumors. Chirurg 84:412–420CrossRefPubMed
7.
go back to reference Yuan C-H, Tao M, Jia Y-M et al (2014) Duodenum-preserving resection and Roux-en-Y pancreatic jejunostomy in benign pancreatic head tumors. World J Gastroenterol 20(44):16786–16792CrossRefPubMedPubMedCentral Yuan C-H, Tao M, Jia Y-M et al (2014) Duodenum-preserving resection and Roux-en-Y pancreatic jejunostomy in benign pancreatic head tumors. World J Gastroenterol 20(44):16786–16792CrossRefPubMedPubMedCentral
8.
go back to reference Palanivelu C, Senthilnathan P, Sabnis SC et al (2017) Randomized clinical trial of laparoscopic versus open pancreatoduodenectomy for periampullarytumours. Br J Surg 104(11):1443–1450CrossRefPubMed Palanivelu C, Senthilnathan P, Sabnis SC et al (2017) Randomized clinical trial of laparoscopic versus open pancreatoduodenectomy for periampullarytumours. Br J Surg 104(11):1443–1450CrossRefPubMed
9.
go back to reference Kutlu Onur C, Lee Jeffrey E, Katz Matthew H et al (2018) Open pancreaticoduodenectomy case volume predicts outcome of laparoscopic approach: a population-based analysis. Ann Surg 267(3):552–560CrossRefPubMed Kutlu Onur C, Lee Jeffrey E, Katz Matthew H et al (2018) Open pancreaticoduodenectomy case volume predicts outcome of laparoscopic approach: a population-based analysis. Ann Surg 267(3):552–560CrossRefPubMed
10.
go back to reference DeRooij T, Lu MZ, Steen MW et al (2016) Minimally invasive versus open pancreatoduodenectomy: systematic review and meta-analysis of comparative cohort and registry studies. Ann Surg 264(2):257–267CrossRef DeRooij T, Lu MZ, Steen MW et al (2016) Minimally invasive versus open pancreatoduodenectomy: systematic review and meta-analysis of comparative cohort and registry studies. Ann Surg 264(2):257–267CrossRef
11.
go back to reference Peng C-H, Shen B-Y, Deng X-X et al (2012) Early experience for the robotic duodenum-preserving pancreatic head resection. World J Surg 36(5):1136–1141CrossRefPubMed Peng C-H, Shen B-Y, Deng X-X et al (2012) Early experience for the robotic duodenum-preserving pancreatic head resection. World J Surg 36(5):1136–1141CrossRefPubMed
12.
go back to reference Zhou JY, Zhou YC, Mou YP et al (2016) Laparoscopic duodenum-preserving pancreatic head resection: a case report. Medicine (Baltimore) 95(32):e4442CrossRef Zhou JY, Zhou YC, Mou YP et al (2016) Laparoscopic duodenum-preserving pancreatic head resection: a case report. Medicine (Baltimore) 95(32):e4442CrossRef
13.
go back to reference Basar O, Brugge WR (2017) My treatment approach: pancreatic cysts. Mayo Clin Proc 92(10):1519–1531CrossRefPubMed Basar O, Brugge WR (2017) My treatment approach: pancreatic cysts. Mayo Clin Proc 92(10):1519–1531CrossRefPubMed
14.
go back to reference Lawrence SA, Attiyeh MA, Seier K et al (2017) Should patients with cystic lesions of the pancreas undergo long-term radiographic surveillance?: Results of 3024 patients evaluated at a single institution. Ann Surg 266(3):536–544CrossRefPubMed Lawrence SA, Attiyeh MA, Seier K et al (2017) Should patients with cystic lesions of the pancreas undergo long-term radiographic surveillance?: Results of 3024 patients evaluated at a single institution. Ann Surg 266(3):536–544CrossRefPubMed
15.
go back to reference Hackert T, Michalski CW, Büchler MW (2017) Mucinous cystic neoplasms of the pancreas: a surgical disease. JAMA Surg 152(1):26CrossRefPubMed Hackert T, Michalski CW, Büchler MW (2017) Mucinous cystic neoplasms of the pancreas: a surgical disease. JAMA Surg 152(1):26CrossRefPubMed
16.
go back to reference Diener MK, Hüttner FJ, Kieser M et al (2017) Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. Lancet 390(10099):1027–1037CrossRefPubMed Diener MK, Hüttner FJ, Kieser M et al (2017) Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. Lancet 390(10099):1027–1037CrossRefPubMed
17.
go back to reference Beger HG, Nakao A, Mayer B et al (2015) Duodenum-preserving total and partial pancreatic head resection for benign tumors—systematic review and meta-analysis. Pancreatology 15(2):167–178CrossRefPubMed Beger HG, Nakao A, Mayer B et al (2015) Duodenum-preserving total and partial pancreatic head resection for benign tumors—systematic review and meta-analysis. Pancreatology 15(2):167–178CrossRefPubMed
18.
go back to reference Beger HG, Mayer B, Rau BM (2016) Parenchyma-sparing, limited pancreatic head resection for benign tumors and low-risk periampullary cancer—a systematic review. J Gastrointest Surg 20(1):206–217CrossRefPubMed Beger HG, Mayer B, Rau BM (2016) Parenchyma-sparing, limited pancreatic head resection for benign tumors and low-risk periampullary cancer—a systematic review. J Gastrointest Surg 20(1):206–217CrossRefPubMed
19.
go back to reference Tsuchikawa T, Hirano S, Tanaka E et al (2013) Modified duodenum-preserving pancreas head resection for low-grade malignant lesion in the pancreatic head. Pancreatology 13(2):170–174CrossRefPubMed Tsuchikawa T, Hirano S, Tanaka E et al (2013) Modified duodenum-preserving pancreas head resection for low-grade malignant lesion in the pancreatic head. Pancreatology 13(2):170–174CrossRefPubMed
Metadata
Title
Laparoscopic duodenum-preserving total pancreatic head resection: a novel surgical approach for benign or low-grade malignant tumors
Authors
Jun Cao
Guo-lin Li
Jin-xing Wei
Wei-Bang Yang
Chang-zhen Shang
Ya-jin Chen
Wan Yee Lau
Jun Min
Publication date
01-02-2019
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 2/2019
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-018-6488-2

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