Skip to main content
Top
Published in: Surgical Endoscopy 8/2018

01-08-2018

Roux-En-Y gastric bypass following failed fundoplication

Authors: Kathleen M. Coakley, Steven A. Groene, Paul D. Colavita, Tanushree Prasad, Dimitris Stefanidis, Amy E. Lincourt, Vedra A. Augenstein, Keith Gersin, B. Todd Heniford

Published in: Surgical Endoscopy | Issue 8/2018

Login to get access

Abstract

Introduction

Roux-En-Y gastric bypass (RYGB) is an alternative to reoperative fundoplication. The aim of this study was to expand long-term outcomes of patients undergoing RYGB after failed fundoplication and assess symptom resolution.

Methods

A single institution prospective study was performed of patients undergoing fundoplication takedown and RYGB between March 2007 and September 2016. Demographics, body mass index (BMI), preoperative symptoms, operative duration and findings, and postoperative outcomes were recorded. Data were assessed using standard statistical methods.

Results

87 patients with failed antireflux surgery underwent RYGB. Median age 58 years (range 25–79 years). Median preoperative BMI 32.4 kg/m2 (range 21.6–50.6 kg/m2). Comorbidities included hypertension (48.3%) and diabetes (11.5%). Sixty-six patients had undergone 1 prior fundoplication, 18 had 2 prior fundoplications, and 3 had 3 prior fundoplications. At least one previous open antireflux procedure had been performed in 16.1% of patients. The most common recurrent symptoms were reflux (85.1%), dysphagia (36.7%), pain (35.6%), and regurgitation (29.9%). Median symptom-free interval from last antireflux surgery was 3 years (range 0–25 years). RYGB was performed laparoscopically in 47.1% of cases, robotically in 44.8% of cases, and open in 5.9%. Operative duration was longer in the robotic group (p = 0.04). During RYGB, 85.1% patients were found to have an associated hiatal hernia, 34.5% had intrathoracic migration of the fundoplication, 32.2% a slipped fundoplication onto proximal stomach, and 13.8% had wrap disruption. Median length of stay (LOS) was 4 days (range 1–33 days). Median follow-up was 35.8 months, 11 patients (12.6%) had recurrent reflux symptoms. Excess body weight loss (%EWL) was 80.4%. There was no mortality but 8 patients required reoperation during follow-up.

Conclusions

Fundoplication takedown with RYGB was successful for long-term reflux resolution. Most can be performed via a minimally invasive approach with acceptable perioperative morbidity, symptom resolution, and the additional benefit of %EWL.
Literature
1.
go back to reference Richter JE (2003) The enormous burden of digestive diseases on our healthcare system. Curr Gastroenterol Rep 5(2):93–94CrossRefPubMed Richter JE (2003) The enormous burden of digestive diseases on our healthcare system. Curr Gastroenterol Rep 5(2):93–94CrossRefPubMed
2.
go back to reference Quiroga E et al (2006) Impaired esophageal function in morbidly obese patients with gastroesophageal reflux disease: evaluation with multichannel intraluminal impedance. Surg Endosc 20(5):739–743CrossRefPubMed Quiroga E et al (2006) Impaired esophageal function in morbidly obese patients with gastroesophageal reflux disease: evaluation with multichannel intraluminal impedance. Surg Endosc 20(5):739–743CrossRefPubMed
3.
go back to reference Fisher BL et al (1999) Obesity correlates with gastroesophageal reflux. Dig Dis Sci 44(11):2290–2294CrossRefPubMed Fisher BL et al (1999) Obesity correlates with gastroesophageal reflux. Dig Dis Sci 44(11):2290–2294CrossRefPubMed
4.
go back to reference Luketich JD et al (2002) Outcomes after minimally invasive reoperation for gastroesophageal reflux disease. Ann Thorac Surg 74(2):328–331 (discussion 331-2)CrossRefPubMed Luketich JD et al (2002) Outcomes after minimally invasive reoperation for gastroesophageal reflux disease. Ann Thorac Surg 74(2):328–331 (discussion 331-2)CrossRefPubMed
5.
go back to reference Aslam M et al (2012) Nonlinear relationship between body mass index and esophageal acid exposure in the extraesophageal manifestations of reflux. Clin Gastroenterol Hepatol 10(8):874–878CrossRefPubMed Aslam M et al (2012) Nonlinear relationship between body mass index and esophageal acid exposure in the extraesophageal manifestations of reflux. Clin Gastroenterol Hepatol 10(8):874–878CrossRefPubMed
6.
go back to reference Colavita PD et al (2013) Nationwide inpatient sample: have antireflux procedures undergone regionalization? J Gastrointest Surg 17(1):6–13 (discussion p 13)CrossRefPubMed Colavita PD et al (2013) Nationwide inpatient sample: have antireflux procedures undergone regionalization? J Gastrointest Surg 17(1):6–13 (discussion p 13)CrossRefPubMed
7.
go back to reference Cookson R et al (2005) Short-term cost effectiveness and long-term cost analysis comparing laparoscopic Nissen fundoplication with proton-pump inhibitor maintenance for gastro-oesophageal reflux disease. Br J Surg 92(6):700–706CrossRefPubMed Cookson R et al (2005) Short-term cost effectiveness and long-term cost analysis comparing laparoscopic Nissen fundoplication with proton-pump inhibitor maintenance for gastro-oesophageal reflux disease. Br J Surg 92(6):700–706CrossRefPubMed
8.
go back to reference Arguedas MR et al (2004) Re-examination of the cost-effectiveness of surgical versus medical therapy in patients with gastroesophageal reflux disease: the value of long-term data collection. Am J Gastroenterol 99(6):1023–1028CrossRefPubMed Arguedas MR et al (2004) Re-examination of the cost-effectiveness of surgical versus medical therapy in patients with gastroesophageal reflux disease: the value of long-term data collection. Am J Gastroenterol 99(6):1023–1028CrossRefPubMed
9.
go back to reference Houghton SG et al (2005) Is Roux-en-Y gastric bypass safe after previous antireflux surgery? Technical feasibility and postoperative symptom assessment. Surg Obes Relat Dis 1(5):475–480CrossRefPubMed Houghton SG et al (2005) Is Roux-en-Y gastric bypass safe after previous antireflux surgery? Technical feasibility and postoperative symptom assessment. Surg Obes Relat Dis 1(5):475–480CrossRefPubMed
10.
go back to reference Prachand VN, Alverdy JC (2010) Gastroesophageal reflux disease and severe obesity: fundoplication or bariatric surgery? World J Gastroenterol 16(30):3757–3761CrossRefPubMedPubMedCentral Prachand VN, Alverdy JC (2010) Gastroesophageal reflux disease and severe obesity: fundoplication or bariatric surgery? World J Gastroenterol 16(30):3757–3761CrossRefPubMedPubMedCentral
11.
go back to reference Furnee EJ et al (2009) Surgical reintervention after failed antireflux surgery: a systematic review of the literature. J Gastrointest Surg 13(8):1539–1549CrossRefPubMedPubMedCentral Furnee EJ et al (2009) Surgical reintervention after failed antireflux surgery: a systematic review of the literature. J Gastrointest Surg 13(8):1539–1549CrossRefPubMedPubMedCentral
12.
go back to reference Dallemagne B et al (2011) Long-term results after laparoscopic reoperation for failed antireflux procedures. Br J Surg 98(11):1581–1587CrossRefPubMed Dallemagne B et al (2011) Long-term results after laparoscopic reoperation for failed antireflux procedures. Br J Surg 98(11):1581–1587CrossRefPubMed
13.
go back to reference Jafari MD et al (2013) Volume and outcome relationship in bariatric surgery in the laparoscopic era. Surg Endosc 27(12):4539–4546CrossRefPubMed Jafari MD et al (2013) Volume and outcome relationship in bariatric surgery in the laparoscopic era. Surg Endosc 27(12):4539–4546CrossRefPubMed
14.
go back to reference Varban OA et al (2015) Hospital volume and outcomes for laparoscopic gastric bypass and adjustable gastric banding in the modern era. Surg Obes Relat Dis 11(2):343–349CrossRefPubMed Varban OA et al (2015) Hospital volume and outcomes for laparoscopic gastric bypass and adjustable gastric banding in the modern era. Surg Obes Relat Dis 11(2):343–349CrossRefPubMed
15.
go back to reference Makris KI et al (2012) The role of short-limb Roux-en-Y reconstruction for failed antireflux surgery: a single-center 5-year experience. Surg Endosc 26(5):1279–1286CrossRefPubMed Makris KI et al (2012) The role of short-limb Roux-en-Y reconstruction for failed antireflux surgery: a single-center 5-year experience. Surg Endosc 26(5):1279–1286CrossRefPubMed
16.
go back to reference Patterson EJ et al (2003) Comparison of objective outcomes following laparoscopic Nissen fundoplication versus laparoscopic gastric bypass in the morbidly obese with heartburn. Surg Endosc 17(10):1561–1565CrossRefPubMed Patterson EJ et al (2003) Comparison of objective outcomes following laparoscopic Nissen fundoplication versus laparoscopic gastric bypass in the morbidly obese with heartburn. Surg Endosc 17(10):1561–1565CrossRefPubMed
17.
go back to reference Nguyen SQ et al (2009) Laparoscopic Roux-en-Y gastric bypass after previous Nissen fundoplication. Surg Obes Relat Dis 5(2):280–282CrossRefPubMed Nguyen SQ et al (2009) Laparoscopic Roux-en-Y gastric bypass after previous Nissen fundoplication. Surg Obes Relat Dis 5(2):280–282CrossRefPubMed
18.
go back to reference Jones KB Jr et al (1991) Roux-Y Gastric Bypass: an effective anti-reflux procedure. Obes Surg 1(3):295–298CrossRefPubMed Jones KB Jr et al (1991) Roux-Y Gastric Bypass: an effective anti-reflux procedure. Obes Surg 1(3):295–298CrossRefPubMed
19.
go back to reference Stefanidis D et al (2012) Laparoscopic fundoplication takedown with conversion to Roux-en-Y gastric bypass leads to excellent reflux control and quality of life after fundoplication failure. Surg Endosc 26(12):3521–3527CrossRefPubMed Stefanidis D et al (2012) Laparoscopic fundoplication takedown with conversion to Roux-en-Y gastric bypass leads to excellent reflux control and quality of life after fundoplication failure. Surg Endosc 26(12):3521–3527CrossRefPubMed
20.
go back to reference Kim M et al (2014) Minimally invasive Roux-en-Y gastric bypass for fundoplication failure offers excellent gastroesophageal reflux control. Am Surg 80(7):696–703PubMed Kim M et al (2014) Minimally invasive Roux-en-Y gastric bypass for fundoplication failure offers excellent gastroesophageal reflux control. Am Surg 80(7):696–703PubMed
21.
go back to reference Khajanchee YS et al (2007) Laparoscopic reintervention for failed antireflux surgery: subjective and objective outcomes in 176 consecutive patients. Arch Surg 142(8):785–901 (discussion 791-2).CrossRefPubMed Khajanchee YS et al (2007) Laparoscopic reintervention for failed antireflux surgery: subjective and objective outcomes in 176 consecutive patients. Arch Surg 142(8):785–901 (discussion 791-2).CrossRefPubMed
22.
go back to reference Mittal SK et al (2013) Roux-en-Y reconstruction is superior to redo fundoplication in a subset of patients with failed antireflux surgery. Surg Endosc 27(3):927–935CrossRefPubMed Mittal SK et al (2013) Roux-en-Y reconstruction is superior to redo fundoplication in a subset of patients with failed antireflux surgery. Surg Endosc 27(3):927–935CrossRefPubMed
23.
go back to reference Makris KI, Lee T, Mittal SK (2009) Roux-en-Y reconstruction for failed fundoplication. J Gastrointest Surg 13(12):2226–2232CrossRefPubMed Makris KI, Lee T, Mittal SK (2009) Roux-en-Y reconstruction for failed fundoplication. J Gastrointest Surg 13(12):2226–2232CrossRefPubMed
24.
go back to reference Furnee EJ et al (2008) Surgical reintervention after antireflux surgery for gastroesophageal reflux disease: a prospective cohort study in 130 patients. Arch Surg 143(3):267–274 (discussion 274).CrossRefPubMed Furnee EJ et al (2008) Surgical reintervention after antireflux surgery for gastroesophageal reflux disease: a prospective cohort study in 130 patients. Arch Surg 143(3):267–274 (discussion 274).CrossRefPubMed
25.
go back to reference Oelschlager BK et al (2006) Medium- and long-term outcome of laparoscopic redo fundoplication. Surg Endosc 20(12):1817–1823CrossRefPubMed Oelschlager BK et al (2006) Medium- and long-term outcome of laparoscopic redo fundoplication. Surg Endosc 20(12):1817–1823CrossRefPubMed
26.
go back to reference Lo Menzo E, Stevens N, Kligman M (2011) Laparoscopic revision of gastrojejunostomy and vagotomy for intractable marginal ulcer after revised gastric bypass. Surg Obes Relat Dis 7(5):656–658CrossRefPubMed Lo Menzo E, Stevens N, Kligman M (2011) Laparoscopic revision of gastrojejunostomy and vagotomy for intractable marginal ulcer after revised gastric bypass. Surg Obes Relat Dis 7(5):656–658CrossRefPubMed
27.
go back to reference Yamamoto SR et al (2014) Long-term outcomes of reintervention for failed fundoplication: redo fundoplication versus Roux-en-Y reconstruction. Surg Endosc 28(1):42–48CrossRefPubMed Yamamoto SR et al (2014) Long-term outcomes of reintervention for failed fundoplication: redo fundoplication versus Roux-en-Y reconstruction. Surg Endosc 28(1):42–48CrossRefPubMed
28.
go back to reference Anderson JE et al (2012) The first national examination of outcomes and trends in robotic surgery in the United States. J Am Coll Surg 215(1):107–114 (discussion 114-6).CrossRefPubMed Anderson JE et al (2012) The first national examination of outcomes and trends in robotic surgery in the United States. J Am Coll Surg 215(1):107–114 (discussion 114-6).CrossRefPubMed
29.
go back to reference Ballantyne GH (2002) Robotic surgery, telerobotic surgery, telepresence, and telementoring. Review of early clinical results. Surg Endosc 16(10):1389–1402CrossRefPubMed Ballantyne GH (2002) Robotic surgery, telerobotic surgery, telepresence, and telementoring. Review of early clinical results. Surg Endosc 16(10):1389–1402CrossRefPubMed
30.
go back to reference Markar SR et al (2011) Robotic vs. laparoscopic Roux-en-Y gastric bypass in morbidly obese patients: systematic review and pooled analysis. Int J Med Robot 7(4):393–400CrossRefPubMed Markar SR et al (2011) Robotic vs. laparoscopic Roux-en-Y gastric bypass in morbidly obese patients: systematic review and pooled analysis. Int J Med Robot 7(4):393–400CrossRefPubMed
31.
go back to reference Hagen ME et al (2012) Reducing cost of surgery by avoiding complications: the model of robotic Roux-en-Y gastric bypass. Obes Surg 22(1):52–61CrossRefPubMed Hagen ME et al (2012) Reducing cost of surgery by avoiding complications: the model of robotic Roux-en-Y gastric bypass. Obes Surg 22(1):52–61CrossRefPubMed
32.
go back to reference Akimoto S et al (2015) Association of body mass index (BMI) with patterns of fundoplication failure: insights gained. J Gastrointest Surg 19(11):1943–1948CrossRefPubMed Akimoto S et al (2015) Association of body mass index (BMI) with patterns of fundoplication failure: insights gained. J Gastrointest Surg 19(11):1943–1948CrossRefPubMed
33.
go back to reference Ghosh SK et al (2005) The mechanical basis of impaired esophageal emptying postfundoplication. Am J Physiol Gastrointest Liver Physiol 289(1):G21–G35CrossRefPubMed Ghosh SK et al (2005) The mechanical basis of impaired esophageal emptying postfundoplication. Am J Physiol Gastrointest Liver Physiol 289(1):G21–G35CrossRefPubMed
Metadata
Title
Roux-En-Y gastric bypass following failed fundoplication
Authors
Kathleen M. Coakley
Steven A. Groene
Paul D. Colavita
Tanushree Prasad
Dimitris Stefanidis
Amy E. Lincourt
Vedra A. Augenstein
Keith Gersin
B. Todd Heniford
Publication date
01-08-2018
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 8/2018
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-018-6072-9

Other articles of this Issue 8/2018

Surgical Endoscopy 8/2018 Go to the issue