Skip to main content
Top
Published in: Surgical Endoscopy 5/2018

01-05-2018

Does hiatal repair affect gastroesophageal reflux symptoms in patients undergoing laparoscopic sleeve gastrectomy?

Authors: Philip Le Page, David Martin, Craig Taylor, Jennifer Wang, Himanshu Wadhawan, Gregory Falk, Simon C. Gibson

Published in: Surgical Endoscopy | Issue 5/2018

Login to get access

Abstract

Background

Laparoscopic sleeve gastrectomy (LSG) has gained popularity as a treatment of choice for morbid obesity and associated comorbidities. There has been a concern about new onset or worsening of gastroesophageal reflux (GERD) following LSG.

Objective

The objective of the study was to evaluate the effect of surgically treating hiatal weakness on GERD symptoms in patients undergoing LSG.

Setting

Single tertiary referral institution, Sydney, Australia.

Methods

A prospective observational cohort study was conducted with consecutive patients undergoing LSG. Hiatal findings, patient demographics, medications and reflux score were recorded prospectively. Patients were followed up post-operatively for a minimum of 12 months and assessed using GERD-HRQL score to quantify reflux symptoms.

Results

Data from 100 patients with a minimum of 1-year follow-up were analysed. Mean follow-up was 18.9 months. Overall, GERD-HRQL improved from mean 4.5 ± 5.8 pre-operatively to 0.76 ± 1.5 after 18.9 months (p = 0.0001). For those with pre-operative reflux, GERD-HRQL improved from mean (SD) 8.43 ± 6.26 pre-operatively to 0.94 ± 1.55 (p = 0.0001). All the nine patients with troublesome daily reflux significantly improved. For those without pre-operative reflux, GERD-HRQL improved from 0.88 ± 1.37 to 0.47 ± 1.25 (p-ns) post-operatively. On multivariate analysis, higher pre-operative reflux and dysphagia/bloat scores, younger age and lower percentage excess weight loss after 18.9 months were associated with GERD-HRQL improvement.

Conclusion

In the medium term, GERD-HRQL improves following sleeve gastrectomy with meticulous hiatal assessment and repair of hiatal laxity and herniation.
Appendix
Available only for authorised users
Literature
1.
go back to reference Peterli R, Borbely Y, Kern B, Gass M, Peters T, Thurnheer M et al (2013) Early results of the Swiss Multicentre Bypass or Sleeve Study (SM-BOSS): a prospective randomized trial comparing laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass. Ann Surg 258(5):690–694 (discussion 5)CrossRefPubMedPubMedCentral Peterli R, Borbely Y, Kern B, Gass M, Peters T, Thurnheer M et al (2013) Early results of the Swiss Multicentre Bypass or Sleeve Study (SM-BOSS): a prospective randomized trial comparing laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass. Ann Surg 258(5):690–694 (discussion 5)CrossRefPubMedPubMedCentral
2.
go back to reference Himpens J, Dapri G, Cadiere GB (2006) A prospective randomized study between laparoscopic gastric banding and laparoscopic isolated sleeve gastrectomy: results after 1 and 3 years. Obes Surg 16(11):1450–1456.CrossRefPubMed Himpens J, Dapri G, Cadiere GB (2006) A prospective randomized study between laparoscopic gastric banding and laparoscopic isolated sleeve gastrectomy: results after 1 and 3 years. Obes Surg 16(11):1450–1456.CrossRefPubMed
3.
go back to reference Brethauer SA, Hammel JP, Schauer PR (2009) Systematic review of sleeve gastrectomy as staging and primary bariatric procedure. Surg Obes Relat Dis 5(4):469–475CrossRefPubMed Brethauer SA, Hammel JP, Schauer PR (2009) Systematic review of sleeve gastrectomy as staging and primary bariatric procedure. Surg Obes Relat Dis 5(4):469–475CrossRefPubMed
5.
go back to reference Tai CM, Huang CK, Lee YC, Chang CY, Lee CT, Lin JT (2013) Increase in gastroesophageal reflux disease symptoms and erosive esophagitis 1 year after laparoscopic sleeve gastrectomy among obese adults. Surg Endosc 27(4):1260–1266CrossRefPubMed Tai CM, Huang CK, Lee YC, Chang CY, Lee CT, Lin JT (2013) Increase in gastroesophageal reflux disease symptoms and erosive esophagitis 1 year after laparoscopic sleeve gastrectomy among obese adults. Surg Endosc 27(4):1260–1266CrossRefPubMed
6.
go back to reference Chiu S, Birch DW, Shi X, Sharma AM, Karmali S (2011) Effect of sleeve gastrectomy on gastroesophageal reflux disease: a systematic review. Surg Obes Relat Dis 7(4):510–515CrossRefPubMed Chiu S, Birch DW, Shi X, Sharma AM, Karmali S (2011) Effect of sleeve gastrectomy on gastroesophageal reflux disease: a systematic review. Surg Obes Relat Dis 7(4):510–515CrossRefPubMed
7.
go back to reference Cottam D, Qureshi FG, Mattar SG, Sharma S, Holover S, Bonanomi G et al (2006) Laparoscopic sleeve gastrectomy as an initial weight-loss procedure for high-risk patients with morbid obesity. Surg Endosc. 20(6):859–863CrossRefPubMed Cottam D, Qureshi FG, Mattar SG, Sharma S, Holover S, Bonanomi G et al (2006) Laparoscopic sleeve gastrectomy as an initial weight-loss procedure for high-risk patients with morbid obesity. Surg Endosc. 20(6):859–863CrossRefPubMed
8.
go back to reference Moon Han S, Kim WW, Oh JH (2005) Results of laparoscopic sleeve gastrectomy (LSG) at 1 year in morbidly obese Korean patients. Obes Surg 15(10):1469–1475CrossRefPubMed Moon Han S, Kim WW, Oh JH (2005) Results of laparoscopic sleeve gastrectomy (LSG) at 1 year in morbidly obese Korean patients. Obes Surg 15(10):1469–1475CrossRefPubMed
9.
go back to reference Melissas J, Daskalakis M, Koukouraki S, Askoxylakis I, Metaxari M, Dimitriadis E et al (2008) Sleeve gastrectomy-a “food limiting” operation. Obes Surg 18(10):1251–1256CrossRefPubMed Melissas J, Daskalakis M, Koukouraki S, Askoxylakis I, Metaxari M, Dimitriadis E et al (2008) Sleeve gastrectomy-a “food limiting” operation. Obes Surg 18(10):1251–1256CrossRefPubMed
10.
go back to reference Melissas J, Koukouraki S, Askoxylakis J, Stathaki M, Daskalakis M, Perisinakis K et al (2007) Sleeve gastrectomy: a restrictive procedure?. Obes Surg;17(1):57–62CrossRefPubMed Melissas J, Koukouraki S, Askoxylakis J, Stathaki M, Daskalakis M, Perisinakis K et al (2007) Sleeve gastrectomy: a restrictive procedure?. Obes Surg;17(1):57–62CrossRefPubMed
11.
go back to reference Omana JJ, Nguyen SQ, Herron D, Kini S (2010) Comparison of comorbidity resolution and improvement between laparoscopic sleeve gastrectomy and laparoscopic adjustable gastric banding. Surg Endosc 24(10):2513–2517CrossRefPubMed Omana JJ, Nguyen SQ, Herron D, Kini S (2010) Comparison of comorbidity resolution and improvement between laparoscopic sleeve gastrectomy and laparoscopic adjustable gastric banding. Surg Endosc 24(10):2513–2517CrossRefPubMed
12.
go back to reference Weiner RA, Weiner S, Pomhoff I, Jacobi C, Makarewicz W, Weigand G (2007) Laparoscopic sleeve gastrectomy–influence of sleeve size and resected gastric volume. Obes Surg 17(10):1297–1305CrossRefPubMed Weiner RA, Weiner S, Pomhoff I, Jacobi C, Makarewicz W, Weigand G (2007) Laparoscopic sleeve gastrectomy–influence of sleeve size and resected gastric volume. Obes Surg 17(10):1297–1305CrossRefPubMed
13.
go back to reference Arias E, Martinez PR, Ka Ming Li V, Szomstein S, Rosenthal RJ (2009) Mid-term follow-up after sleeve gastrectomy as a final approach for morbid obesity. Obes Surg 19(5):544–548CrossRefPubMed Arias E, Martinez PR, Ka Ming Li V, Szomstein S, Rosenthal RJ (2009) Mid-term follow-up after sleeve gastrectomy as a final approach for morbid obesity. Obes Surg 19(5):544–548CrossRefPubMed
14.
go back to reference Frank P, Crookes P (2009) Management of gastroesophageal reflux after sleeve gastrectomy. In: Presented at the second international consensus summit for sleeve gastrectomy (ICSSG) 2009 Frank P, Crookes P (2009) Management of gastroesophageal reflux after sleeve gastrectomy. In: Presented at the second international consensus summit for sleeve gastrectomy (ICSSG) 2009
15.
go back to reference Lakdawala MA, Bhasker A, Mulchandani D, Goel S, Jain S (2010) Comparison between the results of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass in the Indian population: a retrospective 1 year study. Obes Surg 20(1):1–6CrossRefPubMed Lakdawala MA, Bhasker A, Mulchandani D, Goel S, Jain S (2010) Comparison between the results of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass in the Indian population: a retrospective 1 year study. Obes Surg 20(1):1–6CrossRefPubMed
16.
go back to reference Nocca D, Krawczykowsky D, Bomans B, Noel P, Picot MC, Blanc PM et al (2008) A prospective multicenter study of 163 sleeve gastrectomies: results at 1 and 2 years. Obes Surg 18(5):560–565CrossRefPubMed Nocca D, Krawczykowsky D, Bomans B, Noel P, Picot MC, Blanc PM et al (2008) A prospective multicenter study of 163 sleeve gastrectomies: results at 1 and 2 years. Obes Surg 18(5):560–565CrossRefPubMed
17.
go back to reference De Groot NL, Burgerhart JS, Van De Meeberg PC, de Vries DR, Smout AJ, Siersema PD (2009) Systematic review: the effects of conservative and surgical treatment for obesity on gastro-oesophageal reflux disease. Aliment Pharmacol Ther 30(11–12):1091–1102CrossRefPubMed De Groot NL, Burgerhart JS, Van De Meeberg PC, de Vries DR, Smout AJ, Siersema PD (2009) Systematic review: the effects of conservative and surgical treatment for obesity on gastro-oesophageal reflux disease. Aliment Pharmacol Ther 30(11–12):1091–1102CrossRefPubMed
18.
go back to reference Wiklund I (2004) Review of the quality of life and burden of illness in gastroesophageal reflux disease. Dig Dis 22(2):108–114CrossRefPubMed Wiklund I (2004) Review of the quality of life and burden of illness in gastroesophageal reflux disease. Dig Dis 22(2):108–114CrossRefPubMed
19.
go back to reference Abdemur A, Fendrich I, Rosenthal R (2012) Laparoscopic conversion of laparoscopic sleeve gastrectomy to gastric bypass for intractable gastroesophageal reflux disease. Surg Obes Relat Dis 8(5):654CrossRefPubMed Abdemur A, Fendrich I, Rosenthal R (2012) Laparoscopic conversion of laparoscopic sleeve gastrectomy to gastric bypass for intractable gastroesophageal reflux disease. Surg Obes Relat Dis 8(5):654CrossRefPubMed
20.
go back to reference Weiner RA, Theodoridou S, Weiner S (2011) Failure of laparoscopic sleeve gastrectomy–further procedure? Obes Facts 4(Suppl 1):42–46PubMed Weiner RA, Theodoridou S, Weiner S (2011) Failure of laparoscopic sleeve gastrectomy–further procedure? Obes Facts 4(Suppl 1):42–46PubMed
22.
go back to reference Lee YY, McColl KE (2013) Pathophysiology of gastroesophageal reflux disease. Best Pract Res Clin Gastroenterol. 27(3):339–351CrossRefPubMed Lee YY, McColl KE (2013) Pathophysiology of gastroesophageal reflux disease. Best Pract Res Clin Gastroenterol. 27(3):339–351CrossRefPubMed
23.
go back to reference Mans E, Serra-Prat M, Palomera E, Sunol X, Clave P (2015) Sleeve gastrectomy effects on hunger, satiation, and gastrointestinal hormone and motility responses after a liquid meal test. Am J Clin Nutr 102(3):540–547CrossRefPubMed Mans E, Serra-Prat M, Palomera E, Sunol X, Clave P (2015) Sleeve gastrectomy effects on hunger, satiation, and gastrointestinal hormone and motility responses after a liquid meal test. Am J Clin Nutr 102(3):540–547CrossRefPubMed
24.
go back to reference Vigneshwaran B, Wahal A, Aggarwal S, Priyadarshini P, Bhattacharjee H, Khadgawat R et al (2016) Impact of sleeve gastrectomy on type 2 diabetes mellitus, gastric emptying time, glucagon-like peptide 1 (GLP-1), ghrelin and leptin in non-morbidly obese subjects with BMI 30–35.0 kg/m: a prospective study. Obes Surg 26:2817–2823CrossRefPubMed Vigneshwaran B, Wahal A, Aggarwal S, Priyadarshini P, Bhattacharjee H, Khadgawat R et al (2016) Impact of sleeve gastrectomy on type 2 diabetes mellitus, gastric emptying time, glucagon-like peptide 1 (GLP-1), ghrelin and leptin in non-morbidly obese subjects with BMI 30–35.0 kg/m: a prospective study. Obes Surg 26:2817–2823CrossRefPubMed
25.
go back to reference Dolan K, Finch R, Fielding G (2003) Laparoscopic gastric banding and crural repair in the obese patient with a hiatal hernia. Obes Surg 13(5):772–775CrossRefPubMed Dolan K, Finch R, Fielding G (2003) Laparoscopic gastric banding and crural repair in the obese patient with a hiatal hernia. Obes Surg 13(5):772–775CrossRefPubMed
27.
go back to reference Oor JE, Roks DJ, Unlu C, Hazebroek EJ (2016) Laparoscopic sleeve gastrectomy and gastroesophageal reflux disease: a systematic review and meta-analysis. Am J Surg 211(1):250–267CrossRefPubMed Oor JE, Roks DJ, Unlu C, Hazebroek EJ (2016) Laparoscopic sleeve gastrectomy and gastroesophageal reflux disease: a systematic review and meta-analysis. Am J Surg 211(1):250–267CrossRefPubMed
Metadata
Title
Does hiatal repair affect gastroesophageal reflux symptoms in patients undergoing laparoscopic sleeve gastrectomy?
Authors
Philip Le Page
David Martin
Craig Taylor
Jennifer Wang
Himanshu Wadhawan
Gregory Falk
Simon C. Gibson
Publication date
01-05-2018
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 5/2018
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-017-5935-9

Other articles of this Issue 5/2018

Surgical Endoscopy 5/2018 Go to the issue