Skip to main content
Top
Published in: Surgical Endoscopy 4/2018

Open Access 01-04-2018

What are the influencing factors for chronic pain following TAPP inguinal hernia repair: an analysis of 20,004 patients from the Herniamed Registry

Authors: H. Niebuhr, F. Wegner, M. Hukauf, M. Lechner, R. Fortelny, R. Bittner, C. Schug-Pass, F. Köckerling

Published in: Surgical Endoscopy | Issue 4/2018

Login to get access

Abstract

Background

In inguinal hernia repair, chronic pain must be expected in 10–12% of cases. Around one-quarter of patients (2–4%) experience severe pain requiring treatment. The risk factors for chronic pain reported in the literature include young age, female gender, perioperative pain, postoperative pain, recurrent hernia, open hernia repair, perioperative complications, and penetrating mesh fixation. This present analysis of data from the Herniamed Hernia Registry now investigates the influencing factors for chronic pain in male patients after primary, unilateral inguinal hernia repair in TAPP technique.

Methods

In total, 20,004 patients from the Herniamed Hernia Registry were included in uni- and multivariable analyses. For all patients, 1-year follow-up data were available.

Results

Multivariable analysis revealed that onset of pain at rest, on exertion, and requiring treatment was highly significantly influenced, in each case, by younger age (p < 0.001), preoperative pain (p < 0.001), smaller hernia defect (p < 0.001), and higher BMI (p < 0.001). Other influencing factors were postoperative complications (pain at rest p = 0.004 and pain on exertion p = 0.023) and penetrating compared with glue mesh fixation techniques (pain on exertion p = 0.037).

Conclusions

The indication for inguinal hernia surgery should be very carefully considered in a young patient with a small hernia and preoperative pain.
Appendix
Available only for authorised users
Literature
1.
go back to reference Aasvang EK, Gmaehle E, Hansen J, Gmaehle B, Forman JL, Schwarz J, Bittner R, Kehlet H (2010) Predictive risk factors for persistent postherniotomy pain. Anesthesiology 112:957–969CrossRefPubMed Aasvang EK, Gmaehle E, Hansen J, Gmaehle B, Forman JL, Schwarz J, Bittner R, Kehlet H (2010) Predictive risk factors for persistent postherniotomy pain. Anesthesiology 112:957–969CrossRefPubMed
3.
go back to reference Aasvang E, Kehlet H (2005) Surgical management of chronic pain after inguinal hernia repair. Br J Surg 92(7):795–801CrossRefPubMed Aasvang E, Kehlet H (2005) Surgical management of chronic pain after inguinal hernia repair. Br J Surg 92(7):795–801CrossRefPubMed
4.
go back to reference Alfieri S, Amid PK, Campanelli G, Izard G, Kehlet H, Wijsmuller AR, Di Miceli D, Doglietto GB (2011) International guidelines for prevention and management of post-operative chronic pain following inguinal hernia surgery. Hernia 15:239–249. doi:10.1007/s10029-011-0798-9 CrossRefPubMed Alfieri S, Amid PK, Campanelli G, Izard G, Kehlet H, Wijsmuller AR, Di Miceli D, Doglietto GB (2011) International guidelines for prevention and management of post-operative chronic pain following inguinal hernia surgery. Hernia 15:239–249. doi:10.​1007/​s10029-011-0798-9 CrossRefPubMed
7.
go back to reference Simons MP, Aufenacker T, Bay-Nielsen M, Bouillot JL, Campanelli G, Conze J, de Lange D, Fortelny R, Heikkinen T, Kingsnorth A, Kukleta J, Morales-Conde S, Nordin P, Schumeplick V, Smedberg S, Smietanski M, Weber G, Miserez M (2009) European Hernia Society guidelines on the treatment of inguinal hernia in adult patients. Hernia 13:343–403. doi:10.1007/s10029-009-0529-7 CrossRefPubMedPubMedCentral Simons MP, Aufenacker T, Bay-Nielsen M, Bouillot JL, Campanelli G, Conze J, de Lange D, Fortelny R, Heikkinen T, Kingsnorth A, Kukleta J, Morales-Conde S, Nordin P, Schumeplick V, Smedberg S, Smietanski M, Weber G, Miserez M (2009) European Hernia Society guidelines on the treatment of inguinal hernia in adult patients. Hernia 13:343–403. doi:10.​1007/​s10029-009-0529-7 CrossRefPubMedPubMedCentral
8.
go back to reference Miserez M, Peeters E, Aufenacker T, Bouillot JL, Campanelli G, Conze J, Fortelny R, Heikkinen T, Jorgensen LN, Kukleta J, Morales-Conde S, Nordin P, Schumpelick V, Smedberg S, Smietanski M, Weber G, Simons MP (2014) Update with level 1 studies of the European Hernia Society guidelines on the treatment of inguinal hernia in adult patients. Hernia 18:151–163. doi:10.1007/s10029-014-1236-6 CrossRefPubMed Miserez M, Peeters E, Aufenacker T, Bouillot JL, Campanelli G, Conze J, Fortelny R, Heikkinen T, Jorgensen LN, Kukleta J, Morales-Conde S, Nordin P, Schumpelick V, Smedberg S, Smietanski M, Weber G, Simons MP (2014) Update with level 1 studies of the European Hernia Society guidelines on the treatment of inguinal hernia in adult patients. Hernia 18:151–163. doi:10.​1007/​s10029-014-1236-6 CrossRefPubMed
9.
go back to reference Bittner R, Arregui ME, Bisgaard T, Dudai M, Ferzli GS, Fitzgibbons RJ, Fortelny RH, Klinge U, Köckerling F, Kuhry E, Kukleta J, Lomanto D, Misra MC, Montgomery A, Morales-Conde S, Reinpold W, Rosenberg J, Sauerland S, Schug-Paß C, Singh K, Timoey M, Weyhe D, Chowbey P (2011) Guidelines for laparoscopic (TAPP) and endoscopic (TEP) treatment of inguinal Hernia [International Endohernia Society (IEHS)]. Surg Endosc 25:2773–2843. doi:10.1007/s00464-011-1799-6 CrossRefPubMedPubMedCentral Bittner R, Arregui ME, Bisgaard T, Dudai M, Ferzli GS, Fitzgibbons RJ, Fortelny RH, Klinge U, Köckerling F, Kuhry E, Kukleta J, Lomanto D, Misra MC, Montgomery A, Morales-Conde S, Reinpold W, Rosenberg J, Sauerland S, Schug-Paß C, Singh K, Timoey M, Weyhe D, Chowbey P (2011) Guidelines for laparoscopic (TAPP) and endoscopic (TEP) treatment of inguinal Hernia [International Endohernia Society (IEHS)]. Surg Endosc 25:2773–2843. doi:10.​1007/​s00464-011-1799-6 CrossRefPubMedPubMedCentral
10.
go back to reference Bittner R, Montgomery MA, Arregui E, Bansal V, Bingener J, Bisgaard T, Buhck H, Dudai M, Ferzli GS, Fitzgibbons RJ, Fortelny RH, Grimes KL, Klinge U, Köckerling F, Kumar S, Kukleta J, Lomanto D, Misra MC, Morales-Conde S, Reinpold W, Rosenberg J, Singh K, Timoney M, Weyhe D, Chowbey P (2015) Update of guidelines on laparoscopic (TAPP) and endoscopic (TEP) treatment of inguinal hernia (International Endohernia Society). Surg Endosc 29:289–321. doi:10.1007/s00464-014-3917-8 CrossRefPubMed Bittner R, Montgomery MA, Arregui E, Bansal V, Bingener J, Bisgaard T, Buhck H, Dudai M, Ferzli GS, Fitzgibbons RJ, Fortelny RH, Grimes KL, Klinge U, Köckerling F, Kumar S, Kukleta J, Lomanto D, Misra MC, Morales-Conde S, Reinpold W, Rosenberg J, Singh K, Timoney M, Weyhe D, Chowbey P (2015) Update of guidelines on laparoscopic (TAPP) and endoscopic (TEP) treatment of inguinal hernia (International Endohernia Society). Surg Endosc 29:289–321. doi:10.​1007/​s00464-014-3917-8 CrossRefPubMed
11.
go back to reference Poelman MM, van den Heuvel B, Deelder JD, Abis GSA, Beudeker N, Bittner R, Campanelli G, van Dam D, Dwars BJ, Eker HH, Fingerhut A, Khatkov I, Koeckerling F, Kukleta JF, Miserez M, Montgomery A, Munoz Brands RM, Morales Conde S, Muysoms FE, Soltes M, Tromp W, Yavuz Y, Bonjer HJ (2013) EAES Consensus Development Conference on endoscopic repair of groin hernias. Surg Endosc 27:3505–3519. doi:10.1007/s00464-013-3001-9 CrossRefPubMed Poelman MM, van den Heuvel B, Deelder JD, Abis GSA, Beudeker N, Bittner R, Campanelli G, van Dam D, Dwars BJ, Eker HH, Fingerhut A, Khatkov I, Koeckerling F, Kukleta JF, Miserez M, Montgomery A, Munoz Brands RM, Morales Conde S, Muysoms FE, Soltes M, Tromp W, Yavuz Y, Bonjer HJ (2013) EAES Consensus Development Conference on endoscopic repair of groin hernias. Surg Endosc 27:3505–3519. doi:10.​1007/​s00464-013-3001-9 CrossRefPubMed
13.
go back to reference Tam KW, Liang HH, Chai CY (2010) Outcomes of staple fixation of mesh versus nonfixation in laparoscopic total extraperitoneal inguinal repair: a meta-analysis of randomized controlled trials. Word J Surg 34:3065–3074. doi:10.1007/s00268-010-0760-5 CrossRef Tam KW, Liang HH, Chai CY (2010) Outcomes of staple fixation of mesh versus nonfixation in laparoscopic total extraperitoneal inguinal repair: a meta-analysis of randomized controlled trials. Word J Surg 34:3065–3074. doi:10.​1007/​s00268-010-0760-5 CrossRef
14.
go back to reference Teng YJ, Pan SM, Liu YL, Yang KH, Zhang YC, Tian JH, Han JX (2011) A meta-analysis of randomized controlled trials of fixation versus nonfixation of mesh in laparoscopic total extraperitoneal inguinal hernia repair. Surg Endosc 25(9):2849–2858. doi:10.1007/s00464-011-1668-3 CrossRefPubMed Teng YJ, Pan SM, Liu YL, Yang KH, Zhang YC, Tian JH, Han JX (2011) A meta-analysis of randomized controlled trials of fixation versus nonfixation of mesh in laparoscopic total extraperitoneal inguinal hernia repair. Surg Endosc 25(9):2849–2858. doi:10.​1007/​s00464-011-1668-3 CrossRefPubMed
16.
go back to reference Mayer F, Niebuhr H, Lechner M, Dinnewitzer A, Köhler G, Hukauf M, Fortelny RH, Bittner R, Köckerling F (2016) When is mesh fixation in TAPP-repair of primary inguinal hernia repair necessary? The register-based analysis of 11,230 cases. Surg Endosc 30(10):4363–4371. doi:10.1007/s00464-016-4754-8 CrossRefPubMedPubMedCentral Mayer F, Niebuhr H, Lechner M, Dinnewitzer A, Köhler G, Hukauf M, Fortelny RH, Bittner R, Köckerling F (2016) When is mesh fixation in TAPP-repair of primary inguinal hernia repair necessary? The register-based analysis of 11,230 cases. Surg Endosc 30(10):4363–4371. doi:10.​1007/​s00464-016-4754-8 CrossRefPubMedPubMedCentral
17.
go back to reference Kaul A, Hutfless S, Le H, Hamed SA, Tymitz K, Nguyen H, Marohn MR (2012) Staple versus fibrin glue fixation in laparoscopic total extraperitoneal repair of inguinal hernia: a systematic review and meta-analysis. Surg Endosc 26(5):1269–1278. doi:10.1007/s00464-011-2025-2 CrossRefPubMed Kaul A, Hutfless S, Le H, Hamed SA, Tymitz K, Nguyen H, Marohn MR (2012) Staple versus fibrin glue fixation in laparoscopic total extraperitoneal repair of inguinal hernia: a systematic review and meta-analysis. Surg Endosc 26(5):1269–1278. doi:10.​1007/​s00464-011-2025-2 CrossRefPubMed
18.
20.
21.
go back to reference Shi Z, Fan X, Zai S, Zong X, Huang D, Fibrin glue versus staple for mesh fixation in laparoscopic transabdominal preperitoneal repair of inguinal hernia: a meta-analysis and systematic review. Surg Endosc 31:527–537. doi:10.1007/s00464-016-5039-y Shi Z, Fan X, Zai S, Zong X, Huang D, Fibrin glue versus staple for mesh fixation in laparoscopic transabdominal preperitoneal repair of inguinal hernia: a meta-analysis and systematic review. Surg Endosc 31:527–537. doi:10.​1007/​s00464-016-5039-y
22.
go back to reference Lederhuber H, Stiede F, Axer S, Dahlstrand U (2017) Mesh fixation in endoscopic inguinal hernia repair: evaluation of methodology based on a systematic review of randomized clinical trails. Surg Endosc. doi:10.1007/s00464-017-559-x PubMed Lederhuber H, Stiede F, Axer S, Dahlstrand U (2017) Mesh fixation in endoscopic inguinal hernia repair: evaluation of methodology based on a systematic review of randomized clinical trails. Surg Endosc. doi:10.​1007/​s00464-017-559-x PubMed
23.
24.
go back to reference Andresen K, Fenger AQ, Burcharth J, Pommergaard HC, Rosenberg J (2017) Mesh fixation methods and chronic pain after transabdominal preperitoneal (TAPP) inguinal hernia surgery: a comparison between fibrin sealant and tacks. Surg Endoc. doi:10.1007/s00464-017-5454-8 Andresen K, Fenger AQ, Burcharth J, Pommergaard HC, Rosenberg J (2017) Mesh fixation methods and chronic pain after transabdominal preperitoneal (TAPP) inguinal hernia surgery: a comparison between fibrin sealant and tacks. Surg Endoc. doi:10.​1007/​s00464-017-5454-8
26.
27.
go back to reference Miserez M, Alexandre JH, Campanelli G, Corcione F, Cuccurullo D, Pascual MH, Hoeferlin A, Kingsnorth AN, Mandala V, Palot JP, Schumpelick V, Simmermacher RK, Stoppa R, Flament JB (2007) The European hernia society groin hernia classification: simple and easy to remember. Hernia 11(2):113–116. doi:10.1007/s10029-007-0198-3 CrossRefPubMed Miserez M, Alexandre JH, Campanelli G, Corcione F, Cuccurullo D, Pascual MH, Hoeferlin A, Kingsnorth AN, Mandala V, Palot JP, Schumpelick V, Simmermacher RK, Stoppa R, Flament JB (2007) The European hernia society groin hernia classification: simple and easy to remember. Hernia 11(2):113–116. doi:10.​1007/​s10029-007-0198-3 CrossRefPubMed
Metadata
Title
What are the influencing factors for chronic pain following TAPP inguinal hernia repair: an analysis of 20,004 patients from the Herniamed Registry
Authors
H. Niebuhr
F. Wegner
M. Hukauf
M. Lechner
R. Fortelny
R. Bittner
C. Schug-Pass
F. Köckerling
Publication date
01-04-2018
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 4/2018
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-017-5893-2

Other articles of this Issue 4/2018

Surgical Endoscopy 4/2018 Go to the issue